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List of works by J Gerardo Garcia-Lerma

A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation

scientific article

A polyvalent Clade B virus-like particle HIV vaccine combined with partially protective oral preexposure prophylaxis prevents simian-human immunodeficiency virus Infection in macaques and primes for virus-amplified immunity

scientific article

Animal models of antiretroviral prophylaxis for HIV prevention ⬇️

scientific article published on November 1, 2012

Antiretroviral Drug Activity in Macaques Infected during Pre-Exposure Prophylaxis Has a Transient Effect on Cell-Associated SHIV DNA Reservoirs

scientific article

Combination Emtricitabine and Tenofovir Disoproxil Fumarate Prevents Vaginal Simian/Human Immunodeficiency Virus Infection in Macaques Harboring Chlamydia trachomatis and Trichomonas vaginalis

scientific article published on 6 January 2016

Complete protection from repeated vaginal simian-human immunodeficiency virus exposures in macaques by a topical gel containing tenofovir alone or with emtricitabine

scientific article published on 05 August 2009

Depot-medroxyprogesterone acetate does not reduce the prophylactic efficacy of emtricitabine and tenofovir disoproxil fumarate in macaques

scientific article

Diversity of thymidine analogue resistance genotypes among newly diagnosed HIV-1-infected persons

scientific article

Dried blood spots for HIV-1 drug resistance and viral load testing: A review of current knowledge and WHO efforts for global HIV drug resistance surveillance

scientific article published on October 1, 2010

Durable Protection from Vaginal Simian-Human Immunodeficiency Virus Infection in Macaques by Tenofovir Gel and Its Relationship to Drug Levels in Tissue ⬇️

scientific article published on November 9, 2011

Effect of mobile phase pH and organic content on LC-MS analysis of nucleoside and nucleotide HIV reverse transcriptase inhibitors.

scientific article published in May 2009

Evaluation of dried blood spots for human immunodeficiency virus type 1 drug resistance testing

scientific article published on 13 December 2006

Evaluation of the lymphocyte trafficking drug FTY720 in SHIVSF162P3-infected rhesus macaques

scientific article

HIV, transmitted drug resistance, and the paradox of preexposure prophylaxis

scientific article

HIV-1 drug resistance genotyping from dried blood spots stored for 1 year at 4 degrees C

scientific article published on 15 March 2008

Lack of prophylactic efficacy of oral maraviroc in macaques despite high drug concentrations in rectal tissues

scientific article published on 05 June 2013

Limited SHIV env diversification in macaques failing oral antiretroviral pre-exposure prophylaxis ⬇️

scientific article published on May 9, 2012

Measuring Enzymatic HIV-1 Susceptibility to Two Reverse Transcriptase Inhibitors as a Rapid and Simple Approach to HIV-1 Drug-Resistance Testing ⬇️

scientific article published on July 20, 2011

Minority HIV mutation detection in dried blood spots indicates high specimen integrity and reveals hidden archived drug resistance ⬇️

scientific article published on 03 December 2010

Mutation rate and the efficacy of antimicrobial drug treatment.

scientific article

Natural substrate concentrations can modulate the prophylactic efficacy of nucleotide HIV reverse transcriptase inhibitors.

scientific article

Nondaily preexposure prophylaxis for HIV prevention

scientific article published on January 2016

On the Death Rate of Abortively Infected Cells: Estimation from Simian-Human Immunodeficiency Virus Infection

scientific article

On-line coupling of anion exchange and ion-pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors

scientific article published on 11 September 2009

Oral pre-exposure prophylaxis for HIV prevention

scientific article published on 04 December 2009

Pharmacokinetic profile of raltegravir, elvitegravir and dolutegravir in plasma and mucosal secretions in rhesus macaques

scientific article

Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir

scientific article

Prevention of vaginal SHIV transmission in macaques by a coitally-dependent Truvada regimen ⬇️

scientific article published on December 4, 2012

Prophylactic efficacy of oral emtricitabine and tenofovir disoproxil fumarate combination therapy against a tenofovir-resistant simian/human immunodeficiency virus containing the K65R mutation in macaques

scientific article published on 30 April 2013

Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir

scientific article

Protection against Rectal Transmission of an Emtricitabine-Resistant Simian/Human Immunodeficiency Virus SHIV162p3M184VMutant by Intermittent Prophylaxis with Truvada ⬇️

scientific article published on June 1, 2011

Rapid biochemical assays for phenotypic drug resistance testing of HIV-1.

scientific article

Rapid decline in the efficiency of HIV drug resistance genotyping from dried blood spots (DBS) and dried plasma spots (DPS) stored at 37 degrees C and high humidity

scientific article published on 29 April 2009

Reduced Inflammation and CD4 Loss in Acute SHIV Infection During Oral Pre-Exposure Prophylaxis ⬇️

scientific article published on June 27, 2012

SHIV susceptibility changes during the menstrual cycle of pigtail macaques

scientific article

Short communication: Viremic control is independent of repeated low-dose SHIVSF162p3 exposures

scientific article

Susceptibility to Repeated, Low-Dose, Rectal SHIVSF162P3 Challenge Is Independent of TRIM5 Genotype in Rhesus Macaques ⬇️

scientific article published on March 29, 2013

T Cell Chemo-Vaccination Effects after Repeated Mucosal SHIV Exposures and Oral Pre-Exposure Prophylaxis ⬇️

scientific article published on April 26, 2011

Tenofovir diphosphate concentrations and prophylactic effect in a macaque model of rectal simian HIV transmission

scientific article published on 26 May 2014

The epidemiology of antiretroviral drug resistance among drug-naive HIV-1-infected persons in 10 US cities

scientific article published on 21 May 2004

The fitness cost of mutations associated with human immunodeficiency virus type 1 drug resistance is modulated by mutational interactions

scientific article published on 27 December 2006

Topical tenofovir protects against vaginal simian HIV infection in macaques coinfected with Chlamydia trachomatis and Trichomonas vaginalis

scientific article published on 04 January 2017

Transmitted human immunodeficiency virus type 1 carrying the D67N or K219Q/E mutation evolves rapidly to zidovudine resistance in vitro and shows a high replicative fitness in the presence of zidovudine

scientific article

Using geospatial modelling to optimize the rollout of antiretroviral-based pre-exposure HIV interventions in Sub-Saharan Africa

scientific article

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