List of works - Jae Boum Youm

A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation

scientific article

A computational model of cytosolic and mitochondrial [ca] in paced rat ventricular myocytes.

scientific article

A mathematical model of pacemaker activity recorded from mouse small intestine.

scientific article published in May 2006

A step from the physiology to the physiome.

scientific article

Analysis of factors affecting Ca(2+)-dependent inactivation dynamics of L-type Ca(2+) current of cardiac myocytes in pulmonary vein of rabbit

scientific article published on 06 June 2012

Angiotensin II inhibits inward rectifier K+ channels in rabbit coronary arterial smooth muscle cells through protein kinase Cα

scientific article published on 19 January 2006

BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes

scientific article published on 22 July 2020

Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine

scientific article published in May 2004

Cardiac inotropy, lusitropy, and Ca2+ handling with major metabolic substrates in rat heart

scientific article

Characterization of a novel LQT3 variant with a selective efficacy of mexiletine treatment

scientific article published on 10 September 2019

Circadian modulation of the cardiac proteome underpins differential adaptation to morning and evening exercise training: an LC-MS/MS analysis

scientific article published on 06 February 2020

Class 3 inhibition of hERG K+ channel by caffeic acid phenethyl ester (CAPE) and curcumin

scientific article published on 26 February 2013

Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells

scientific article published on 25 October 2013

Computational prediction of proarrhythmogenic effect of the V241F KCNQ1 mutation in human atrium.

scientific article published on 16 September 2014

Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling

scientific article published on 15 May 2013

Direct inhibition of a PKA inhibitor, H-89 on KV channels in rabbit coronary arterial smooth muscle cells.

scientific article published on 23 January 2006

Direct modulation of Ca(2+)-activated K(+) current by H-89 in rabbit coronary arterial smooth muscle cells

scientific article published on 08 September 2006

Does strong hypertrophic condition induce fast mitochondrial DNA mutation of rabbit heart?

scientific article published in April 2008

Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells

scientific article

Echinochrome A regulates phosphorylation of phospholamban Ser16 and Thr17 suppressing cardiac SERCA2A Ca²⁺ reuptake

scientific article

Effects of streptozotocin and unilateral nephrectomy on L-type Ca²⁺ channels and membrane capacitance in arteriolar smooth muscle cells.

scientific article published on 9 September 2014

Electrophysiological modelling of pulmonary artery smooth muscle cells in the rabbits--special consideration to the generation of hypoxic pulmonary vasoconstriction

scientific article published on 07 August 2007

Electrophysiological properties and calcium handling of embryonic stem cell-derived cardiomyocytes.

scientific article published on 7 January 2016

Endothelin-1 inhibits inward rectifier K+ channels in rabbit coronary arterial smooth muscle cells through protein kinase C.

scientific article

Erratum to: Spontaneous inward currents reflecting oscillatory activation of Na+/Ca2+ exchangers in human embryonic stem cell-derived cardiomyocytes.

scientific article published in July 2016

Exercise as A Potential Therapeutic Target for Diabetic Cardiomyopathy: Insight into the Underlying Mechanisms ⬇️

scientific article published on 12 December 2019

Facilitation by intracellular carbonic anhydrase of Na+ -HCO3- co-transport but not Na+ / H+ exchange activity in the mammalian ventricular myocyte.

scientific article published on 2 December 2013

Generation of PDGFRα+ Cardioblasts from Pluripotent Stem Cells

scientific article

H⁺-activated Na⁺ influx in the ventricular myocyte couples Ca²⁺-signalling to intracellular pH.

scientific article published on 18 April 2013

Identification of potential target genes of cardioprotection against ischemia-reperfusion injury by express sequence tags analysis in rat hearts

scientific article

Mitochondrial Ca2+-activated K+ channels more efficiently reduce mitochondrial Ca2+ overload in rat ventricular myocytes.

scientific article

Mitochondrial pyruvate dehydrogenase phosphatase 1 regulates the early differentiation of cardiomyocytes from mouse embryonic stem cells

scientific article published on 19 August 2016

Modeling of arrhythmogenic automaticity induced by stretch in rat atrial myocytes.

scientific article published on 31 October 2008

Modeling of stochastic behavior of pacemaker potential in interstitial cells of Cajal.

scientific article published on 17 September 2014

Modulation by melatonin of the cardiotoxic and antitumor activities of adriamycin

scientific article

Modulation of HERG channel inactivation by external cations ⬇️

scientific article published on October 29, 2003

Modulation of L-type Ca²⁺ channel activity by neuronal nitric oxide synthase and myofilament Ca²⁺ sensitivity in cardiac myocytes from hypertensive rat.

scientific article published on 10 June 2015

Na-K-2Cl Cotransporter and Store-Operated Ca2+ Entry in Pacemaking by Interstitial Cells of Cajal

scientific article published on 19 July 2019

Nitric oxide-cGMP-protein kinase G signaling pathway induces anoxic preconditioning through activation of ATP-sensitive K+ channels in rat hearts.

scientific article

Non-genomic effect of glucocorticoids on cardiovascular system

scientific article published on 23 September 2012

Potassium currents in isolated deiters' cells of Guinea pig.

scientific article

Potential biomarkers for ischemic heart damage identified in mitochondrial proteins by comparative proteomics

scientific article

Pu-18-N-butylimide-NMGA-GNP conjugate is effective against hepatocellular carcinoma

scientific article published on 13 June 2013

Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts

scientific article published on 14 October 2017

Role of Stretch-activated Channels in the Heart: Action Potential and Ca2+ Transients

Role of stretch-activated channels on the stretch-induced changes of rat atrial myocytes

scientific article

Simulated hyperglycemia in rat cardiomyocytes: a proteomics approach for improved analysis of cellular alterations.

scientific article published in August 2007

Simulation of Ca2+-activated Cl- current of cardiomyocytes in rabbit pulmonary vein: implications of subsarcolemmal Ca2+ dynamics.

scientific article published in May 2006

Simulation of spontaneous action potentials of cardiomyocytes in pulmonary veins of rabbits

scientific article published on 11 August 2007

Site specific differential activation of ras/raf/ERK signaling in rabbit isoproterenol-induced left ventricular hypertrophy.

scientific article published on 5 August 2006

Spontaneous inward currents reflecting oscillatory activation of Na⁺/Ca²⁺ exchangers in human embryonic stem cell-derived cardiomyocytes

scientific article published on 21 December 2015

Stretch-activated currents in cardiomyocytes isolated from rabbit pulmonary veins.

scientific article

Stretch-activated non-selective cation channel: a causal link between mechanical stretch and atrial natriuretic peptide secretion

scientific article published on 20 June 2008

Subunit composition of ATP-sensitive potassium channels in mitochondria of rat hearts

scientific journal article

Teaching cardiac excitation-contraction coupling using a mathematical computer simulation model of human ventricular myocytes

scientific article published on 01 September 2020

The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action

scientific article published on 17 October 2012

The protein kinase A inhibitor, H-89, directly inhibits KATP and Kir channels in rabbit coronary arterial smooth muscle cells

scientific article published on 28 December 2005

List of works by Jae Boum Youm

A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation

A computational model of cytosolic and mitochondrial [ca] in paced rat ventricular myocytes.

A mathematical model of pacemaker activity recorded from mouse small intestine.

A step from the physiology to the physiome.

Analysis of factors affecting Ca(2+)-dependent inactivation dynamics of L-type Ca(2+) current of cardiac myocytes in pulmonary vein of rabbit

Angiotensin II inhibits inward rectifier K+ channels in rabbit coronary arterial smooth muscle cells through protein kinase Cα

BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes

Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine

Cardiac inotropy, lusitropy, and Ca2+ handling with major metabolic substrates in rat heart

Characterization of a novel LQT3 variant with a selective efficacy of mexiletine treatment

Circadian modulation of the cardiac proteome underpins differential adaptation to morning and evening exercise training: an LC-MS/MS analysis

Class 3 inhibition of hERG K+ channel by caffeic acid phenethyl ester (CAPE) and curcumin

Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells

Computational prediction of proarrhythmogenic effect of the V241F KCNQ1 mutation in human atrium.

Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling

Direct inhibition of a PKA inhibitor, H-89 on KV channels in rabbit coronary arterial smooth muscle cells.

Direct modulation of Ca(2+)-activated K(+) current by H-89 in rabbit coronary arterial smooth muscle cells

Does strong hypertrophic condition induce fast mitochondrial DNA mutation of rabbit heart?

Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells

Echinochrome A regulates phosphorylation of phospholamban Ser16 and Thr17 suppressing cardiac SERCA2A Ca²⁺ reuptake

Effects of streptozotocin and unilateral nephrectomy on L-type Ca²⁺ channels and membrane capacitance in arteriolar smooth muscle cells.

Electrophysiological modelling of pulmonary artery smooth muscle cells in the rabbits--special consideration to the generation of hypoxic pulmonary vasoconstriction

Electrophysiological properties and calcium handling of embryonic stem cell-derived cardiomyocytes.

Endothelin-1 inhibits inward rectifier K+ channels in rabbit coronary arterial smooth muscle cells through protein kinase C.

Erratum to: Spontaneous inward currents reflecting oscillatory activation of Na+/Ca2+ exchangers in human embryonic stem cell-derived cardiomyocytes.

Exercise as A Potential Therapeutic Target for Diabetic Cardiomyopathy: Insight into the Underlying Mechanisms ⬇️

Facilitation by intracellular carbonic anhydrase of Na+ -HCO3- co-transport but not Na+ / H+ exchange activity in the mammalian ventricular myocyte.

Generation of PDGFRα+ Cardioblasts from Pluripotent Stem Cells

H⁺-activated Na⁺ influx in the ventricular myocyte couples Ca²⁺-signalling to intracellular pH.

Identification of potential target genes of cardioprotection against ischemia-reperfusion injury by express sequence tags analysis in rat hearts

Mitochondrial Ca2+-activated K+ channels more efficiently reduce mitochondrial Ca2+ overload in rat ventricular myocytes.

Mitochondrial pyruvate dehydrogenase phosphatase 1 regulates the early differentiation of cardiomyocytes from mouse embryonic stem cells

Modeling of arrhythmogenic automaticity induced by stretch in rat atrial myocytes.

Modeling of stochastic behavior of pacemaker potential in interstitial cells of Cajal.

Modulation by melatonin of the cardiotoxic and antitumor activities of adriamycin

Modulation of HERG channel inactivation by external cations ⬇️

Modulation of L-type Ca²⁺ channel activity by neuronal nitric oxide synthase and myofilament Ca²⁺ sensitivity in cardiac myocytes from hypertensive rat.

Na-K-2Cl Cotransporter and Store-Operated Ca2+ Entry in Pacemaking by Interstitial Cells of Cajal

Nitric oxide-cGMP-protein kinase G signaling pathway induces anoxic preconditioning through activation of ATP-sensitive K+ channels in rat hearts.

Non-genomic effect of glucocorticoids on cardiovascular system

Potassium currents in isolated deiters' cells of Guinea pig.

Potential biomarkers for ischemic heart damage identified in mitochondrial proteins by comparative proteomics

Pu-18-N-butylimide-NMGA-GNP conjugate is effective against hepatocellular carcinoma

Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts

Role of Stretch-activated Channels in the Heart: Action Potential and Ca2+ Transients

Role of stretch-activated channels on the stretch-induced changes of rat atrial myocytes

Simulated hyperglycemia in rat cardiomyocytes: a proteomics approach for improved analysis of cellular alterations.

Simulation of Ca2+-activated Cl- current of cardiomyocytes in rabbit pulmonary vein: implications of subsarcolemmal Ca2+ dynamics.

Simulation of spontaneous action potentials of cardiomyocytes in pulmonary veins of rabbits

Site specific differential activation of ras/raf/ERK signaling in rabbit isoproterenol-induced left ventricular hypertrophy.

Spontaneous inward currents reflecting oscillatory activation of Na⁺/Ca²⁺ exchangers in human embryonic stem cell-derived cardiomyocytes

Stretch-activated currents in cardiomyocytes isolated from rabbit pulmonary veins.

Stretch-activated non-selective cation channel: a causal link between mechanical stretch and atrial natriuretic peptide secretion

Subunit composition of ATP-sensitive potassium channels in mitochondria of rat hearts

Teaching cardiac excitation-contraction coupling using a mathematical computer simulation model of human ventricular myocytes

The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action

The protein kinase A inhibitor, H-89, directly inhibits KATP and Kir channels in rabbit coronary arterial smooth muscle cells