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List of works by Ethan Dmitrovsky

A phase I trial and in vitro studies combining ABT-751 with carboplatin in previously treated non-small cell lung cancer patients

scientific article published on 12 November 2012

A proof-of-principle clinical trial of bexarotene in patients with non-small cell lung cancer

scientific article

A retinoic acid--rich tumor microenvironment provides clonal survival cues for tumor-specific CD8(+) T cells

scientific article published on 17 August 2012

A retinoic acid-dependent checkpoint in the development of CD4+ T cell-mediated immunity

scientific article

All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched

scientific article published on 04 February 2014

Anaphase catastrophe is a target for cancer therapy

scientific article

Bexarotene and erlotinib for aerodigestive tract cancer

scientific article

Bexarotene plus erlotinib suppress lung carcinogenesis independent of KRAS mutations in two clinical trials and transgenic models

scientific article

Blockade of the Ubiquitin Protease UBP43 Destabilizes Transcription Factor PML/RARα and Inhibits the Growth of Acute Promyelocytic Leukemia ⬇️

scientific article published on October 8, 2010

CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110

scientific article

Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2

scientific article (publication date: 29 May 2002)

Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer

scientific article published on 16 May 2013

Cyclin D1 as a target for chemoprevention

scientific article

Cyclin E transgenic mice: discovery tools for lung cancer biology, therapy, and prevention

scientific article

Cyclin degradation for cancer therapy and chemoprevention

scientific article published on November 2007

Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2.

scientific article published on 22 August 2016

Effective capture of circulating tumor cells from a transgenic mouse lung cancer model using dendrimer surfaces immobilized with anti-EGFR

scientific article published on 27 August 2015

Evidence for tankyrases as antineoplastic targets in lung cancer.

scientific article

Evidence for the ubiquitin protease UBP43 as an antineoplastic target

scientific article

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

scientific article

G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program

scientific article published on 2 February 2016

G0S2 is an all-trans-retinoic acid target gene.

scientific article published on August 2008

G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer

scientific article

Gene profiling uncovers retinoid target genes

scientific article published on January 2007

High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors

scientific article

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

scientific article published on 27 June 2013

Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemia

scientific article

Involvement of microRNAs in lung cancer biology and therapy

scientific article

MCL1 enhances the survival of CD8+ memory T Cells after viral infection

scientific article

Mice lacking G0S2 are lean and cold-tolerant

scientific article

Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas

scientific article published on 10 November 2015

MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

scientific article

Microarray analyses uncover UBE1L as a candidate target gene for lung cancer chemoprevention

scientific article

Microarray analysis uncovers retinoid targets in human bronchial epithelial cells

scientific article

Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer

scientific article

Nonclassical retinoids and lung carcinogenesis

scientific article

Repression of cyclin D1 as a target for germ cell tumors.

scientific article published on February 2007

Repression of exogenous gene expression by the retinoic acid target gene G0S2.

scientific article published on 28 March 2013

Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations

scientific article published on 22 August 2012

Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity

scientific article

Retinoid chemoprevention trials: cyclin D1 in the crosshairs

scientific article published on January 2009

Retinoid targets in cancer therapy and chemoprevention

scientific article published on July 1, 2003

Retinoids and rexinoids in cancer prevention: from laboratory to clinic

scientific article published on 25 September 2015

Retinoids in cancer therapy and chemoprevention: promise meets resistance ⬇️

scientific article published on October 20, 2003

Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown

scientific article

Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy

scientific article published on April 2004

Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe

scientific article

The ISG15-specific protease USP18 regulates stability of PTEN.

scientific article published on 12 December 2016

The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis

scientific article

Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas

scholarly article

UBE1L causes lung cancer growth suppression by targeting cyclin D1.

scientific article published on December 2008

UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia

scientific article

UBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylation

scientific article

Uncovering growth-suppressive MicroRNAs in lung cancer

scientific article published on February 2009

Uncovering novel targets for cancer chemoprevention.

scientific article published on January 2007

Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

scientific article

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