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List of works by Nathan Osman

Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.

scientific article

Antiviral Activity of Bictegravir and Cabotegravir Against Integrase Inhibitor Resistant SIVmac239 and HIV-1.

scientific article published on 18 September 2017

Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase.

scientific article published in January 2014

Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase.

scientific article published in June 2014

Biochemical analysis of the role of G118R-linked dolutegravir drug resistance substitutions in HIV-1 integrase

scientific article published on 30 September 2013

Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase

scientific article

Does antiretroviral treatment change HIV-1 codon usage patterns in its genes: a preliminary bioinformatics study

scientific article

Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout

scientific article

Durable suppression of HIV-1 with resistance mutations to integrase inhibitors by dolutegravir following drug washout

article

Evaluation of Sofosbuvir (β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine) as an inhibitor of Dengue virus replication

scientific article published on 24 July 2017

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness

scientific article published on 17 January 2014

The R263K substitution in HIV-1 subtype C is more deleterious for integrase enzymatic function and viral replication than in subtype B.

scientific article published on July 2015

The Role of Phylogenetics in Unravelling Patterns of HIV Transmission towards Epidemic Control: The Quebec Experience (2002–2020)

journal article from 'Viruses' published in 2021

Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure

scientific article published on 22 February 2013