List of works - Kebreab Ghebreselasie

123I-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation ⬇️

scientific article published on November 12, 2010

Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2.

scientific article published on 30 March 2015

Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors

scientific article

Chemical stability of 2-arachidonylglycerol under biological conditions

scientific article published in October 2002

Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance.

scientific article

Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics

scientific article

Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2′-Des-methyl-sulindac Sulfide Scaffold ⬇️

scientific article published on February 14, 2012

Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors.

scientific article

Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents

scientific article published on 28 March 2013

Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer

scientific article published on 24 May 2019

Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site

scientific article

Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site

scientific article published on 18 April 2019

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer ⬇️

scientific article published on September 7, 2011

Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization

scientific article

Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors

scientific article published on 14 February 2020

Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network

scientific article

PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.

scientific article

Targeted Detection of Cyclooxygenase-1 in Ovarian Cancer

scientific article published on 24 July 2019

Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe

scientific article published on May 2015

Trifluoromethyl fluorocoxib a detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts

scientific article

nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2

scientific article published on 18 June 2015

List of works by Kebreab Ghebreselasie

123I-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation ⬇️

Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2.

Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors

Chemical stability of 2-arachidonylglycerol under biological conditions

Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance.

Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics

Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2′-Des-methyl-sulindac Sulfide Scaffold ⬇️

Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors.

Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents

Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer

Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site

Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer ⬇️

Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization

Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors

Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network

PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.

Targeted Detection of Cyclooxygenase-1 in Ovarian Cancer

Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe

Trifluoromethyl fluorocoxib a detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts

nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2