List of works - Brenda C Crews

123I-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation ⬇️

scientific article published on November 12, 2010

Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors

scientific article published in February 2002

Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors

scientific article

Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance.

scientific article

Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance.

scientific article

Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging.

scientific article published on January 2012

Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2′-Des-methyl-sulindac Sulfide Scaffold ⬇️

scientific article published on February 14, 2012

Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors.

scientific article

Design, Synthesis, and Structure–Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase-2 as Targeted Optical Imaging Agents ⬇️

scientific article published on March 28, 2013

Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer

scientific article published on 24 May 2019

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer ⬇️

scientific article published on September 7, 2011

Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization

scientific article

Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer

scientific article

Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors

scientific article published on 14 February 2020

How changes in reimbursement have affected the state of Georgia.

scientific article published in December 2003

In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG.

scholarly article

Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors

scientific article published on 19 September 2005

Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice

scientific article published in August 2005

Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis

scientific article published on 23 August 2016

Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry ⬇️

scientific article

Metabolism in vitro and in vivo of the DNA base adduct, M1G.

scientific article

Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides

scientific article published on 19 September 2002

PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.

scientific article

Podophyllotoxin analogues active versus Trypanosoma brucei

scientific article

Progress toward the total synthesis of lucentamycin A: total synthesis and biological evaluation of 8-epi-lucentamycin A.

scientific article

Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6

scientific article

Seeing it through: translational validation of new medical imaging modalities

scientific article

Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents

scientific article

Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells

scientific article published on 10 February 2010

Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites

scientific article

Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes

scientific article

Targeted Detection of Cyclooxygenase-1 in Ovarian Cancer

scientific article published on 24 July 2019

Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe

scientific article published on May 2015

The 2′-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor ⬇️

scientific article published on March 25, 2013

The glyceryl ester of prostaglandin E2 mobilizes calcium and activates signal transduction in RAW264.7 cells

scholarly article

Total Synthesis of (+)-7-Bromotrypargine and Unnatural Analogues: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic Relevance ⬇️

scientific article published on November 16, 2011

Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs

scientific article

Trifluoromethyl fluorocoxib a detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts

scientific article

nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2

scientific article published on 18 June 2015

List of works by Brenda C Crews

123I-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation ⬇️

Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors

Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors

Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance.

Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance.

Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging.

Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2′-Des-methyl-sulindac Sulfide Scaffold ⬇️

Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors.

Design, Synthesis, and Structure–Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase-2 as Targeted Optical Imaging Agents ⬇️

Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer ⬇️

Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization

Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer

Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors

How changes in reimbursement have affected the state of Georgia.

In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG.

Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors

Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice

Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis

Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry ⬇️

Metabolism in vitro and in vivo of the DNA base adduct, M1G.

Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides

PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.

Podophyllotoxin analogues active versus Trypanosoma brucei

Progress toward the total synthesis of lucentamycin A: total synthesis and biological evaluation of 8-epi-lucentamycin A.

Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6

Seeing it through: translational validation of new medical imaging modalities

Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents

Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells

Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites

Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes

Targeted Detection of Cyclooxygenase-1 in Ovarian Cancer

Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe

The 2′-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor ⬇️

The glyceryl ester of prostaglandin E2 mobilizes calcium and activates signal transduction in RAW264.7 cells

Total Synthesis of (+)-7-Bromotrypargine and Unnatural Analogues: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic Relevance ⬇️

Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs

Trifluoromethyl fluorocoxib a detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts

nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2