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List of works by Demian Obregon

ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein

scientific article

Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α: implications for autism.

scientific article published on 15 November 2011

Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders

scientific article published on 07 June 2011

Autoreactive‐Aβ antibodies promote APP β‐secretase processing ⬇️

scientific article published on January 23, 2012

Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model

scientific article

CD40 is expressed and functional on neuronal cells

scientific article

CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice ⬇️

scientific article published on January 26, 2011

Clinical repetitive transcranial magnetic stimulation for veterans with major depressive disorder

scientific article published in November 2017

EGCG functions through estrogen receptor‐mediated activation of ADAM10 in the promotion of non‐amyloidogenic processing of APP ⬇️

scientific article published on September 17, 2010

EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-gamma: role of JAK/STAT1 signaling and implications for HIV-associated dementia

scientific article published on 31 October 2006

Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).

scientific article

Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production

scientific article

Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD).

scientific article published on 11 January 2011

GFAP expression and social deficits in transgenic mice overexpressing human sAPPα.

scientific article published on 10 July 2013

Inflammaging as a prodrome to Alzheimer's disease

scientific article

Inhibition of angiogenesis by Abeta peptides

scientific article published on January 2004

Luteolin reduces Alzheimer's disease pathologies induced by traumatic brain injury.

scientific article published on 9 January 2014

Memantine and catatonia: a case report and literature review

scientific article published on July 2011

Modulation of neuronal differentiation by CD40 isoforms

scientific article

Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology

scientific article

Mycoplasma hyorhinis markedly degrades β-amyloid peptides in vitro and ex vivo: a novel biological approach for treating Alzheimer's disease?

scientific article published on 25 September 2013

Peripheral biomarkers in Autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosis

scientific article published on 15 October 2008

Potential Autoepitope within the Extracellular Region of Contactin-Associated Protein-like 2 in Mice

scientific article published on January 2014

Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain.

scientific article published on September 2002

Psychotropic effects of antimicrobials and immune modulation by psychotropics: implications for neuroimmune disorders

scientific article

Rapamycin promotes beta-amyloid production via ADAM-10 inhibition

scientific article

Recyclable single-stranded DNA template for synthesis of siRNAs ⬇️

scientific article published on November 1, 2010

Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice

scientific article published in December 2002

Rosiglitazone reduces serum homocysteine levels, smooth muscle proliferation, and intimal hyperplasia in Sprague-Dawley rats fed a high methionine diet

scientific article published in May 2005

Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway

scientific article

Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation ⬇️

scientific article published on April 10, 2012

Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae

scientific article published in April 2002

Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

scientific article

The immunology of traumatic brain injury: a prime target for Alzheimer's disease prevention.

scientific article published on August 2012

The role of glycogen synthase kinase-3 signaling in neurodevelopment and fragile X syndrome ⬇️

scientific article published on September 20, 2012

Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage

scholarly article

Treatment decisions for chronic tic disorders

p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro

scientific article published on 01 August 2002

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