List of works - Jun Tan

A Draft Sequence of the Rice Genome (Oryza sativa L. ssp. indica)

scientific article

ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein

scientific article

Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders

scientific article published on 07 June 2011

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

scientific article published on 25 September 2008

Autoreactive‐Aβ antibodies promote APP β‐secretase processing ⬇️

scientific article published on January 23, 2012

Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model

scientific article

Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model.

scientific article

Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase

scientific article published on October 2008

CD40 is expressed and functional on neuronal cells

scientific article

CD40-CD40L interaction in Alzheimer's disease.

scientific article

CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice ⬇️

scientific article published on January 26, 2011

CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice

scientific article

CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation

scientific article

Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors

scientific article published in April 2004

Clearance of amyloid-beta in Alzheimer's disease: shifting the action site from center to periphery

scientific article published on 15 April 2014

Cytokine correlations in youth with tic disorders

scientific article

EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-gamma: role of JAK/STAT1 signaling and implications for HIV-associated dementia

scientific article published on 31 October 2006

EVALUATION OF HOW CIGARETTE SMOKE IS A DIRECT RISK FACTOR FOR ALZHEIMER'S DISEASE ⬇️

scientific article published on January 1, 2012

Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).

scientific article

Effects of blue-green algae extracts on the proliferation of human adult stem cells in vitro: a preliminary study

scientific article

Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice

scientific article

Fish oil enhances anti-amyloidogenic properties of green tea EGCG in Tg2576 mice

scientific article

Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production

scientific article

Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD).

scientific article published on 11 January 2011

Green Tea-EGCG reduces GFAP associated neuronal loss in HIV-1 Tat transgenic mice.

scientific article published on January 2009

Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

scientific article published in September 2005

HIV-1 Tat contributes to Alzheimer's disease-like pathology in PSAPP mice

scientific article published on 30 January 2009

HIV-1 Tat-induced microglial activation and neuronal damage is inhibited via CD45 modulation: A potential new treatment target for HAND.

scientific article

Human umbilical cord blood-derived monocytes improve cognitive deficits and reduce amyloid-β pathology in PSAPP mice.

scientific article published on 30 July 2015

Immunity and Alzheimer's disease: immunological perspectives on the development of novel therapies

scientific article published on 13 August 2013

Immunotherapy for Alzheimer disease: the challenge of adverse effects.

scientific article published on 03 July 2012

Impact of the CD40-CD40L dyad in Alzheimer's disease

scientific article published on April 2010

Improving lithium therapeutics by crystal engineering of novel ionic cocrystals

scientific article published on 18 November 2013

Inflammaging as a prodrome to Alzheimer's disease

scientific article

LISPRO mitigates β-amyloid and associated pathologies in Alzheimer's mice.

scientific article published on 15 June 2017

MSM ameliorates HIV-1 Tat induced neuronal oxidative stress via rebalance of the glutathione cycle

scientific article

Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice

scientific article

Microglia activation as a biomarker for traumatic brain injury

scientific article published on 26 March 2013

Modulation of neuronal differentiation by CD40 isoforms

scientific article

Multiple Low-Dose Infusions of Human Umbilical Cord Blood Cells Improve Cognitive Impairments and Reduce Amyloid-β-Associated Neuropathology in Alzheimer Mice ⬇️

scientific article published on September 5, 2012

Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology

scientific article

Mycoplasma hyorhinis markedly degrades β-amyloid peptides in vitro and ex vivo: a novel biological approach for treating Alzheimer's disease?

scientific article published on 25 September 2013

Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production

scientific article published in May 2004

Normal brain aging clinical, immunological, neuropsychological, and neuroimaging features.

scientific article published on January 2009

Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation

scientific article published in 2013

Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds.

scientific article

Peripheral biomarkers in Autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosis

scientific article published on 15 October 2008

Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice

scientific article published on June 2008

Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease

scientific article

Psychiatric implications of hepatitis-C infection

scientific article published on January 2007

Rapamycin promotes beta-amyloid production via ADAM-10 inhibition

scientific article

Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway

scientific article

Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation ⬇️

scientific article published on April 10, 2012

Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

scientific article

Suppressed cytokine expression immediatey following traumatic brain injury in neonatal rats indicates an expeditious endogenous anti-inflammatory response

scientific article

Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.

scientific article published on 19 June 2015

T-cells in Alzheimer's disease.

scientific article

Tannic Acid Is a Natural β-Secretase Inhibitor That Prevents Cognitive Impairment and Mitigates Alzheimer-like Pathology in Transgenic Mice ⬇️

scientific article published on January 4, 2012

The immunology of traumatic brain injury: a prime target for Alzheimer's disease prevention.

scientific article published on August 2012

The microglial "activation" continuum: from innate to adaptive responses

scientific article

The role of glycogen synthase kinase-3 signaling in neurodevelopment and fragile X syndrome ⬇️

scientific article published on September 20, 2012

The role of tau protein in HIV-associated neurocognitive disorders

scientific article

Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage

scholarly article

List of works by Jun Tan

A Draft Sequence of the Rice Genome (Oryza sativa L. ssp. indica)

ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein

Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

Autoreactive‐Aβ antibodies promote APP β‐secretase processing ⬇️

Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model

Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model.

Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase

CD40 is expressed and functional on neuronal cells

CD40-CD40L interaction in Alzheimer's disease.

CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice ⬇️

CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice

CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation

Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors

Clearance of amyloid-beta in Alzheimer's disease: shifting the action site from center to periphery

Cytokine correlations in youth with tic disorders

EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-gamma: role of JAK/STAT1 signaling and implications for HIV-associated dementia

EVALUATION OF HOW CIGARETTE SMOKE IS A DIRECT RISK FACTOR FOR ALZHEIMER'S DISEASE ⬇️

Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).

Effects of blue-green algae extracts on the proliferation of human adult stem cells in vitro: a preliminary study

Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice

Fish oil enhances anti-amyloidogenic properties of green tea EGCG in Tg2576 mice

Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production

Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD).

Green Tea-EGCG reduces GFAP associated neuronal loss in HIV-1 Tat transgenic mice.

Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

HIV-1 Tat contributes to Alzheimer's disease-like pathology in PSAPP mice

HIV-1 Tat-induced microglial activation and neuronal damage is inhibited via CD45 modulation: A potential new treatment target for HAND.

Human umbilical cord blood-derived monocytes improve cognitive deficits and reduce amyloid-β pathology in PSAPP mice.

Immunity and Alzheimer's disease: immunological perspectives on the development of novel therapies

Immunotherapy for Alzheimer disease: the challenge of adverse effects.

Impact of the CD40-CD40L dyad in Alzheimer's disease

Improving lithium therapeutics by crystal engineering of novel ionic cocrystals

Inflammaging as a prodrome to Alzheimer's disease

LISPRO mitigates β-amyloid and associated pathologies in Alzheimer's mice.

MSM ameliorates HIV-1 Tat induced neuronal oxidative stress via rebalance of the glutathione cycle

Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice

Microglia activation as a biomarker for traumatic brain injury

Modulation of neuronal differentiation by CD40 isoforms

Multiple Low-Dose Infusions of Human Umbilical Cord Blood Cells Improve Cognitive Impairments and Reduce Amyloid-β-Associated Neuropathology in Alzheimer Mice ⬇️

Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology

Mycoplasma hyorhinis markedly degrades β-amyloid peptides in vitro and ex vivo: a novel biological approach for treating Alzheimer's disease?

Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production

Normal brain aging clinical, immunological, neuropsychological, and neuroimaging features.

Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation

Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds.

Peripheral biomarkers in Autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosis

Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice

Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease

Psychiatric implications of hepatitis-C infection

Rapamycin promotes beta-amyloid production via ADAM-10 inhibition

Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway

Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation ⬇️

Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

Suppressed cytokine expression immediatey following traumatic brain injury in neonatal rats indicates an expeditious endogenous anti-inflammatory response

Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.

T-cells in Alzheimer's disease.

Tannic Acid Is a Natural β-Secretase Inhibitor That Prevents Cognitive Impairment and Mitigates Alzheimer-like Pathology in Transgenic Mice ⬇️

The immunology of traumatic brain injury: a prime target for Alzheimer's disease prevention.

The microglial "activation" continuum: from innate to adaptive responses

The role of glycogen synthase kinase-3 signaling in neurodevelopment and fragile X syndrome ⬇️

The role of tau protein in HIV-associated neurocognitive disorders

Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage