List of works - Jacqueline Marchand-Brynaert

(Di)-aminoguanidine Functionalization through Transamination: An Avenue to an Auspicious Class of Supramolecular Synthons

scientific article published on 7 September 2011

(S)-1-(Pent-4'-enoyl)-4-(hydroxymethyl)-azetidin-2-one derivatives as inhibitors of human fatty acid amide hydrolase (hFAAH): synthesis, biological evaluation and molecular modelling

scientific article published on 09 October 2013

1-Alkoxycarbonyl-3-halogenoazetidin-2-ones as elastase (PPE) inhibitors

scientific article published in December 2002

12- to 22-membered bridged β-lactams as potential penicillin-binding protein inhibitors

scientific article published on 08 December 2011

1D iron(II) spin crossover complexes with 1,2,4-triazol-4-yl-propanoic acid

scientific article published on 8 November 2011

1β-Methylcarbapenem intermediates via the thiolysis of a Meldrum's precursor

scientific article published in December 2001

2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis

scientific article

3-Alkenyl-2-azetidinones as fatty acid amide hydrolase inhibitors

scientific article published on 24 May 2008

A graftable LDV peptidomimetic: design, synthesis and application to a blood filtration membrane

scientific article published on 8 December 2007

A metal–organic framework made of an asymmetric 1,2,4-triazole and tetrazole ligand

scientific article published in 2012

A phosphonated triarylmethyl radical as a probe for measurement of pH by EPR

scientific article published on 08 February 2012

A practical molecular clip for immobilization of receptors and biomolecules on devices' surface: synthesis, grafting protocol and analytical assay

scientific article published in July 2005

A pyrene- and phosphonate-containing fluorescent probe as guest molecule in a host polymer matrix.

scientific article published in February 2013

Adsorption properties of the penicillin derivative DTPA on gold substrates

scientific article published on 01 May 2007

An unprecedented reversible mode of action of β-lactams for the inhibition of human fatty acid amide hydrolase (hFAAH).

scientific article published on 29 November 2012

An unprecedented surface oxidation of polystyrene substrates by wet chemistry under basic conditions

scientific article

Aroma extraction dilution analysis of Sauternes wines. Key role of polyfunctional thiols

scientific article published on 01 September 2006

Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone

scientific article published on 18 October 2011

Calcium and zinc complexes of pyrroglutamate analogs detected by electrospray ionization mass spectrometry

scientific article published on 27 July 2010

Cell adhesive PET membranes by surface grafting of RGD peptidomimetics.

scientific article published on 18 January 2005

Characterization of an endophytic whorl-forming Streptomyces from Catharanthus roseus stems producing polyene macrolide antibiotic

scientific article published on 23 April 2012

Chemistry around imidazopyrazine and ibuprofen: discovery of novel fatty acid amide hydrolase (FAAH) inhibitors

scientific article published on 11 May 2010

Chiral properties of tetrathiatriarylmethyl spin probes

scientific article published on 15 March 2011

Clickable PEG conjugate obtained by “clip” photochemistry: Synthesis and characterization by quantitative 19F NMR

Coelenterazine: a two-stage antioxidant in lipid micelles

scientific article published in February 2004

Combined experimental and theoretical study on the Raman and Raman optical activity signatures of pentamethylundecane diastereoisomers

scientific article published on September 2010

Configurationally Stable Tris(tetrathioaryl)methyl Molecular Propellers

Coordination Polymers and Metal Organic Frameworks Derived from 1,2,4-Triazole Amino Acid Linkers

scientific article published on 11 October 2011

Coupling occurs before breakdown during biotransformation of Acid Blue 62 by white rot fungi

scientific article published on 6 September 2007

DOSY-NMR analysis of ring-closing metathesis (RCM) products from β-lactam precursors

scientific article published on 17 November 2011

Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method

scientific article published on 14 December 2015

Design and evaluation of analogues of the bacterial cell-wall peptidoglycan motif L-Lys-D-Ala-D-Ala for use in a vancomycin biosensor

scientific article published on 28 August 2007

Design, synthesis and evaluation of graftable thrombin inhibitors for the preparation of blood-compatible polymer materials.

scientific article

Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.

scientific article published on 6 May 2009

Divergent and regioselective synthesis of 1,2,4- and 1,2,5-trisubstituted imidazoles

scientific article

Functionalization of the PEG Corona of Nanoparticles by Clip Photochemistry in Water: Application to the Grafting of RGD Ligands on PEGylated USPIO Imaging Agent

scientific article

Impact of ligand spacer and counter-anion in selected 1D iron(II) spin crossover coordination polymers

scientific article published on 13 October 2011

In vitro and in vivo studies of 6,8-(diaryl)imidazo[1,2-a]pyrazin-3(7H)-ones as new antioxidants.

scientific article published on 15 May 2009

In vivo EPR extracellular pH-metry in tumors using a triphosphonated trityl radical.

scientific article

Inhibitors of the endocannabinoid-degrading enzymes, or how to increase endocannabinoid's activity by preventing their hydrolysis

scientific article published on April 2012

Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

scientific article published on 16 May 2015

LDV peptidomimetics equipped with biotinylated spacer-arms: synthesis and biological evaluation on CCRF-CEM cell line

scientific article

Laccase-mediated synthesis of novel substituted phenoxazine chromophores featuring tuneable water solubility

scientific article published in August 2009

Large ring 1,3-bridged 2-azetidinones: experimental and theoretical studies

scientific article published on 26 October 2008

Light induced functionalization of PCL-PEG block copolymers for the covalent immobilization of biomolecules

scientific article published in April 2009

Live-cell imaging with water-soluble aminophenoxazinone dyes synthesised through laccase biocatalysis

scientific article

Macrocycle-embedded β-lactams as novel inhibitors of the Penicillin Binding Protein PBP2a from MRSA.

scientific article

Non-symmetrically substituted phenoxazinones from laccase-mediated oxidative cross-coupling of aminophenols: an experimental and theoretical insight

scientific article published on 18 January 2012

Novel RGD-like molecules based on the tyrosine template: design, synthesis, and biological evaluation on isolated integrins alphaVbeta3/alphaIIbbeta3 and in cellular adhesion tests

scientific article published in October 2004

PCL-PEG-based nanoparticles grafted with GRGDS peptide: preparation and surface analysis by XPS.

scientific article published in December 2007

PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination

scientific article

Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation

scientific article

Perfluorinated markers for hypoxia detection: synthesis of sulfur-containing precursors and [18F]-labelling

scientific article published in February 2005

Phosphonated Benzoxazole Derivatives: Synthesis and Metal-Complexing Properties

scientific article published on 18 March 2013

Photo-induced micellization of block copolymers bearing 4,5-dimethoxy-2-nitrobenzyl side groups

Polyethylene terephthalate membrane grafted with peptidomimetics: endothelial cell compatibility and retention under shear stress.

scientific article published on 13 August 2012

Preparation of (3S,4S)-1-Benzhydryl-3-[(5R)-1′-hydroxyethyl]-4-acyl-2-azetidinones from (2R,3R)-Epoxybutyramide Precursors

scientific article published in May 2000

Protection of peroxide-treated fish erythrocytes by coelenterazine and coelenteramine

scientific article published in September 2002

Protective effect of imidazolopyrazinone antioxidants on ischemia/reperfusion injury

scientific article published in February 2003

Regioselective Baeyer-Villiger oxidation in 4-carbonyl-2-azetidinone series: a revisited route toward carbapenem precursor

scientific article published in April 2004

Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic

scientific article published on 23 July 2011

Routes to novel mono- and bis-tetrazole compounds: synthesis, spectroscopic and structural characterization

scientific article published in 2013

SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process

scientific article published on 20 September 2011

Selective Protection and Deprotection of ortho-Functionalized Arylphosphonates

scientific article published on 2 December 2011

Selective thin-layer chromatography of 4-R-1,2,4-triazoles

scientific article published on 26 December 2006

Self-assembling doxorubicin-tocopherol succinate prodrug as a new drug delivery system: synthesis, characterization, and in vitro and in vivo anticancer activity

scientific article

Spin state tuning in FeII 1D coordination polymers made of 1,2,4-triazol-4-yl-propanoic and butanoic acids

scientific article published on 12 October 2012

Stability of meropenem and doripenem solutions for administration by continuous infusion

scientific article published on 21 February 2010

Superlative Scaffold of 1,2,4-Triazole Derivative of Glycine Steering Linear Chain to a Chiral Helicate

scientific article published on 6 April 2011

Surface functionalization of a poly(butylene terephthalate) (PBT) melt-blown filtration membrane by wet chemistry and photo-grafting

scientific article published in January 2007

Surface functionalization of germanium ATR devices for use in FTIR-biosensors

scientific article published on 24 December 2008

Surface modification of polypropylene nonwovens with LDV peptidomimetics and their application in the leukodepletion of blood products

scientific article published on 12 June 2012

Synthesis and evaluation of N1/C4-substituted beta-lactams as PPE and HLE inhibitors

scientific article published in January 2004

Synthesis and evaluation of a small library of graftable thrombin inhibitors derived from (L)-arginine

scientific article

Synthesis of (1′R,3S,4S)-3-[1′-(tert-Butyldimethylsilyloxy)ethyl]- 4-(cyclopropylcarbonyloxy)azetidin-2-one

scientific article published in August 2006

Synthesis of poly(lactide-co-glycolide-co-ε-caprolactone)-graft-mannosylated poly(ethylene oxide) copolymers by combination of "clip" and "click" chemistries

scientific article

Synthesis of two persistent fluorinated tetrathiatriarylmethyl (TAM) radicals for biomedical EPR applications.

scientific article published on 3 July 2008

Synthesis, structure-activity relationship and in vitro evaluation of coelenterazine and coelenteramine derivatives as inhibitors of lipid peroxidation

scientific article published in February 2003

Targeted nanoparticles with novel non-peptidic ligands for oral delivery

scientific article published on 20 February 2013

Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination

scientific article published on 4 May 2009

Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles

scientific article published on 01 January 2012

Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with paclitaxel

scientific article published on 20 August 2009

Ultrasmall particle of iron oxide--RGD peptidomimetic conjugate: synthesis and characterisation.

scientific article published on 4 February 2010

Vibrational circular dichroism versus optical rotation dispersion and electronic circular dichroism for diastereomers: the stereochemistry of 3-(1'-hydroxyethyl)-1-(3'-phenylpropanoyl)-azetidin-2-one.

scientific article published on 17 May 2012

Zinc complexes with 1,2,4-triazole functionalized amino acid derivatives: Synthesis, structure and β-lactamase assay

scientific article published in March 2011

[4 + 2] Cycloadditions of 1-phosphono-1,3-butadienes with nitroso heterodienophiles: a versatile synthetic route for polyfunctionalized aminophosphonic derivatives

scientific article published on August 2010

alphavbeta3 Integrin-targeting Arg-Gly-Asp (RGD) peptidomimetics containing oligoethylene glycol (OEG) spacers

scientific article published in November 2009

beta-Lactams derived from a carbapenem chiron are selective inhibitors of human fatty acid amide hydrolase versus human monoacylglycerol lipase

scientific article

{4(S)-(Piperidin-1-ylcarbonyl)-4-[3-(trifluoromethyl)phenylsulfonamido]butyl}guanidinium chloride: a model of a graftable thrombin inhibitor

scientific article published on 22 November 2006

“Clip” and “Click” Chemistries Combination: Toward Easy PEGylation of Degradable Aliphatic Polyesters

scientific article published on 07 March 2011

List of works by Jacqueline Marchand-Brynaert

(Di)-aminoguanidine Functionalization through Transamination: An Avenue to an Auspicious Class of Supramolecular Synthons

(S)-1-(Pent-4'-enoyl)-4-(hydroxymethyl)-azetidin-2-one derivatives as inhibitors of human fatty acid amide hydrolase (hFAAH): synthesis, biological evaluation and molecular modelling

1-Alkoxycarbonyl-3-halogenoazetidin-2-ones as elastase (PPE) inhibitors

12- to 22-membered bridged β-lactams as potential penicillin-binding protein inhibitors

1D iron(II) spin crossover complexes with 1,2,4-triazol-4-yl-propanoic acid

1β-Methylcarbapenem intermediates via the thiolysis of a Meldrum's precursor

2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis

3-Alkenyl-2-azetidinones as fatty acid amide hydrolase inhibitors

A graftable LDV peptidomimetic: design, synthesis and application to a blood filtration membrane

A metal–organic framework made of an asymmetric 1,2,4-triazole and tetrazole ligand

A phosphonated triarylmethyl radical as a probe for measurement of pH by EPR

A practical molecular clip for immobilization of receptors and biomolecules on devices' surface: synthesis, grafting protocol and analytical assay

A pyrene- and phosphonate-containing fluorescent probe as guest molecule in a host polymer matrix.

Adsorption properties of the penicillin derivative DTPA on gold substrates

An unprecedented reversible mode of action of β-lactams for the inhibition of human fatty acid amide hydrolase (hFAAH).

An unprecedented surface oxidation of polystyrene substrates by wet chemistry under basic conditions

Aroma extraction dilution analysis of Sauternes wines. Key role of polyfunctional thiols

Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone

Calcium and zinc complexes of pyrroglutamate analogs detected by electrospray ionization mass spectrometry

Cell adhesive PET membranes by surface grafting of RGD peptidomimetics.

Characterization of an endophytic whorl-forming Streptomyces from Catharanthus roseus stems producing polyene macrolide antibiotic

Chemistry around imidazopyrazine and ibuprofen: discovery of novel fatty acid amide hydrolase (FAAH) inhibitors

Chiral properties of tetrathiatriarylmethyl spin probes

Clickable PEG conjugate obtained by “clip” photochemistry: Synthesis and characterization by quantitative 19F NMR

Coelenterazine: a two-stage antioxidant in lipid micelles

Combined experimental and theoretical study on the Raman and Raman optical activity signatures of pentamethylundecane diastereoisomers

Configurationally Stable Tris(tetrathioaryl)methyl Molecular Propellers

Coordination Polymers and Metal Organic Frameworks Derived from 1,2,4-Triazole Amino Acid Linkers

Coupling occurs before breakdown during biotransformation of Acid Blue 62 by white rot fungi

DOSY-NMR analysis of ring-closing metathesis (RCM) products from β-lactam precursors

Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method

Design and evaluation of analogues of the bacterial cell-wall peptidoglycan motif L-Lys-D-Ala-D-Ala for use in a vancomycin biosensor

Design, synthesis and evaluation of graftable thrombin inhibitors for the preparation of blood-compatible polymer materials.

Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.

Divergent and regioselective synthesis of 1,2,4- and 1,2,5-trisubstituted imidazoles

Functionalization of the PEG Corona of Nanoparticles by Clip Photochemistry in Water: Application to the Grafting of RGD Ligands on PEGylated USPIO Imaging Agent

Impact of ligand spacer and counter-anion in selected 1D iron(II) spin crossover coordination polymers

In vitro and in vivo studies of 6,8-(diaryl)imidazo[1,2-a]pyrazin-3(7H)-ones as new antioxidants.

In vivo EPR extracellular pH-metry in tumors using a triphosphonated trityl radical.

Inhibitors of the endocannabinoid-degrading enzymes, or how to increase endocannabinoid's activity by preventing their hydrolysis

Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

LDV peptidomimetics equipped with biotinylated spacer-arms: synthesis and biological evaluation on CCRF-CEM cell line

Laccase-mediated synthesis of novel substituted phenoxazine chromophores featuring tuneable water solubility

Large ring 1,3-bridged 2-azetidinones: experimental and theoretical studies

Light induced functionalization of PCL-PEG block copolymers for the covalent immobilization of biomolecules

Live-cell imaging with water-soluble aminophenoxazinone dyes synthesised through laccase biocatalysis

Macrocycle-embedded β-lactams as novel inhibitors of the Penicillin Binding Protein PBP2a from MRSA.

Non-symmetrically substituted phenoxazinones from laccase-mediated oxidative cross-coupling of aminophenols: an experimental and theoretical insight

Novel RGD-like molecules based on the tyrosine template: design, synthesis, and biological evaluation on isolated integrins alphaVbeta3/alphaIIbbeta3 and in cellular adhesion tests

PCL-PEG-based nanoparticles grafted with GRGDS peptide: preparation and surface analysis by XPS.

PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination

Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation

Perfluorinated markers for hypoxia detection: synthesis of sulfur-containing precursors and [18F]-labelling

Phosphonated Benzoxazole Derivatives: Synthesis and Metal-Complexing Properties

Photo-induced micellization of block copolymers bearing 4,5-dimethoxy-2-nitrobenzyl side groups

Polyethylene terephthalate membrane grafted with peptidomimetics: endothelial cell compatibility and retention under shear stress.

Preparation of (3S,4S)-1-Benzhydryl-3-[(5R)-1′-hydroxyethyl]-4-acyl-2-azetidinones from (2R,3R)-Epoxybutyramide Precursors

Protection of peroxide-treated fish erythrocytes by coelenterazine and coelenteramine

Protective effect of imidazolopyrazinone antioxidants on ischemia/reperfusion injury

Regioselective Baeyer-Villiger oxidation in 4-carbonyl-2-azetidinone series: a revisited route toward carbapenem precursor

Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic

Routes to novel mono- and bis-tetrazole compounds: synthesis, spectroscopic and structural characterization

SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process

Selective Protection and Deprotection of ortho-Functionalized Arylphosphonates

Selective thin-layer chromatography of 4-R-1,2,4-triazoles

Self-assembling doxorubicin-tocopherol succinate prodrug as a new drug delivery system: synthesis, characterization, and in vitro and in vivo anticancer activity

Spin state tuning in FeII 1D coordination polymers made of 1,2,4-triazol-4-yl-propanoic and butanoic acids

Stability of meropenem and doripenem solutions for administration by continuous infusion

Superlative Scaffold of 1,2,4-Triazole Derivative of Glycine Steering Linear Chain to a Chiral Helicate

Surface functionalization of a poly(butylene terephthalate) (PBT) melt-blown filtration membrane by wet chemistry and photo-grafting

Surface functionalization of germanium ATR devices for use in FTIR-biosensors

Surface modification of polypropylene nonwovens with LDV peptidomimetics and their application in the leukodepletion of blood products

Synthesis and evaluation of N1/C4-substituted beta-lactams as PPE and HLE inhibitors

Synthesis and evaluation of a small library of graftable thrombin inhibitors derived from (L)-arginine

Synthesis of (1′R,3S,4S)-3-[1′-(tert-Butyldimethylsilyloxy)ethyl]- 4-(cyclopropylcarbonyloxy)azetidin-2-one

Synthesis of poly(lactide-co-glycolide-co-ε-caprolactone)-graft-mannosylated poly(ethylene oxide) copolymers by combination of "clip" and "click" chemistries

Synthesis of two persistent fluorinated tetrathiatriarylmethyl (TAM) radicals for biomedical EPR applications.

Synthesis, structure-activity relationship and in vitro evaluation of coelenterazine and coelenteramine derivatives as inhibitors of lipid peroxidation

Targeted nanoparticles with novel non-peptidic ligands for oral delivery