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List of works by Michael A. Hollingsworth

A Polymeric Nanogel-Based Treatment Regimen for Enhanced Efficacy and Sequential Administration of Synergistic Drug Combination in Pancreatic Cancer

scientific article published on 25 January 2019

A micropapillary pattern is predictive of a poor prognosis in lung adenocarcinoma, and reduced surfactant apoprotein A expression in the micropapillary pattern is an excellent indicator of a poor prognosis

scientific article published on 13 April 2007

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

scientific article

A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma

scientific article

ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression

scientific article published on 01 January 2008

Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas

scientific article published on 8 June 2016

Advances in Biomedical Imaging, Bioengineering, and Related Technologies for the Development of Biomarkers of Pancreatic Disease: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases and National Institute of Biomedical Imag

scientific article

Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis

scientific article

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs

scientific article

Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma

scientific article

CCL21 induces extensive intratumoral immune cell infiltration and specific anti-tumor cellular immunity

scientific article published on 01 March 2007

Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins

scientific article published on November 2007

Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression

scientific article published on December 2006

Combination of mAb-AR20.5, anti-PD-L1 and PolyICLC inhibits tumor progression and prolongs survival of MUC1.Tg mice challenged with pancreatic tumors

scientific article published on 4 December 2017

Comparative phenotypes of peripheral blood and spleen cells from cancer patients

scientific article published on 07 June 2020

Comparison of ras-responsive gene enhancers in pancreatic tumor cells that express either wild-type or mutant K-ras

scientific article published on 28 February 2009

Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell line

scientific article published on 01 August 2003

Correction: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy

scientific article published on 23 June 2020

Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras

scientific article

Definitive Characterization of CA 19-9 in Resectable Pancreatic Cancer Using a Reference Set of Serum and Plasma Specimens

scientific article published on 2 October 2015

Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma

scientific article

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

scientific article

Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.

scientific article published on 6 March 2013

Early detection of sporadic pancreatic cancer: summative review

scientific article

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

scientific article

Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis

scientific article published on 5 August 2013

Flt3 ligand delivered in a pluronic formulation prolongs the survival of mice with orthotopic pancreatic adenocarcinoma

scientific article

Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas

scientific article published on 14 September 2020

Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.

scientific article

Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis

scientific article published on 23 May 2016

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma

scientific article

Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma

scientific article published on 27 March 2019

Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases

scientific article published on 24 January 2019

Interactions between MUC1 and p120 catenin regulate dynamic features of cell adhesion, motility, and metastasis

scientific article

Invasive phenotype induced by low extracellular pH requires mitochondria dependent metabolic flexibility

scientific article published on 18 February 2020

Isoforms of MUC16 Activate Oncogenic Signaling Through EGF Receptors to Enhance the Progression of Pancreatic Cancer

scientific article published on 24 December 2020

Local and systemic immunosuppression in pancreatic cancer: Targeting the stalwarts in tumor's arsenal

scientific article published on 21 June 2020

MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion

scientific article published on November 2007

MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer ⬇️

scientific article published on August 6, 2012

MUC1 regulates expression of multiple microRNAs involved in pancreatic tumor progression, including the miR-200c/141 cluster

scientific article

MUC1-specific anti-tumor responses: molecular requirements for CD4-mediated responses

scientific article published on August 2002

MUC4 expression increases progressively in pancreatic intraepithelial neoplasia

scientific article published on 01 May 2002

MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type

scientific article published in January 2004

MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells

scientific article

Macrophage-Derived Neuropilin-2 Exhibits Novel Tumor-Promoting Functions

scientific article published on 15 August 2018

Macrophages potentiate STAT3 signaling in skeletal muscles and regulate pancreatic cancer cachexia

scientific article published on 25 April 2020

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer

scientific article

Molecular pathology of early pancreatic cancer ⬇️

scientific article published on January 1, 2010

Molecular requirements for CD8-mediated rejection of a MUC1-expressing pancreatic carcinoma: implications for tumor vaccines

scientific article published on 04 May 2002

Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis

scientific article published on 23 July 2019

Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin

scientific article published on 27 June 2003

Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.

scientific article published on 21 September 2016

Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer

article

Overexpression of Ecdysoneless in Pancreatic Cancer and Its Role in Oncogenesis by Regulating Glycolysis ⬇️

scientific article published on September 12, 2012

Pathologic features of mucin-producing bile duct tumors: two histopathologic categories as counterparts of pancreatic intraductal papillary-mucinous neoplasms

scientific article

Phase I/II Trial of Neoadjuvant Oregovomab-based Chemoimmunotherapy Followed by Stereotactic Body Radiotherapy and Nelfinavir For Locally Advanced Pancreatic Adenocarcinoma

scientific article published on 01 October 2019

Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells

scientific article published on June 2007

Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning

scientific article published on 28 January 2020

Purification and characterization of a human pancreatic adenocarcinoma mucin

scientific article

RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells

scientific article published on May 2006

Regulation of Aerobic Glycolysis by microRNAs in Cancer ⬇️

scientific article published on January 1, 2011

Relationships and differentially expressed genes among pancreatic cancers examined by large-scale serial analysis of gene expression.

scientific article

Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells

scientific article

Rosiglitazone and Gemcitabine in combination reduces immune suppression and modulates T cell populations in pancreatic cancer ⬇️

scientific article published on 05 August 2012

SIRT1-NOX4 signaling axis regulates cancer cachexia

scientific article published on 01 July 2020

SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells

scientific article published on 26 April 2016

Sonic hedgehog promotes desmoplasia in pancreatic cancer

scientific article published on October 2008

Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation

scientific article published on 24 April 2020

Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma

scientific article published on 16 January 2018

Tapasin decreases immune responsiveness to a model tumor antigen

scientific article published on July 2004

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

scientific article published on 17 April 2019

The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice

scientific article

The glycoprotein mucin-1 negatively regulates GalNAc transferase 5 expression in pancreatic cancer

scientific article published on 21 July 2019

The human RNA polymerase II-associated factor 1 (hPaf1): a new regulator of cell-cycle progression

scientific article

The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays

scientific article published on 17 April 2009

Total pancreatectomy and islet autotransplantation in chronic pancreatitis: recommendations from PancreasFest

scientific article

Tumor-specific immunity in MUC1.Tg mice induced by immunization with peptide vaccines from the cytoplasmic tail of CD227 (MUC1).

scientific article published on December 2004

Upregulation of ZIP14 and Altered Zinc Homeostasis in Muscles in Pancreatic Cancer Cachexia

scientific article published on 18 December 2019

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

scientific article published on 07 September 2015

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