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List of works by Makoto Asashima

A Novel Therapeutic Strategy for Pancreatic Cancer: Targeting Cell Surface Glycan Using rBC2LC-N Lectin-Drug Conjugate (LDC).

scientific article

A crucial role of a high mobility group protein HMGA2 in cardiogenesis

scientific article

A lectin-based glycomic approach to identify characteristic features of Xenopus embryogenesis

scientific article

A medium hyperglycosylated podocalyxin enables noninvasive and quantitative detection of tumorigenic human pluripotent stem cells

scientific article published on 12 February 2014

A novel gene, BENI is required for the convergent extension during Xenopus laevis gastrulation

scientific article published on 11 November 2006

A stable chimeric fibroblast growth factor (FGF) can successfully replace basic FGF in human pluripotent stem cell culture

scientific article

Activin A regulates growth of gastro-intestinal epithelial cells by mediating epithelial-mesenchymal interaction

scientific article

An in vitro reconstitution system for the assessment of chromatin protein fluidity during Xenopus development

article

BMP signaling regulates the differentiation of mouse embryonic stem cells into lung epithelial cell lineages

scientific article published on 7 March 2013

BMP4 induction of trophoblast from mouse embryonic stem cells in defined culture conditions on laminin

scientific article

Bestrophin genes are expressed in Xenopus development

scientific article published on 4 May 2009

Biosynthesis of Ribosomal RNA in Nucleoli Regulates Pluripotency and Differentiation Ability of Pluripotent Stem Cells

scientific article published on 01 December 2014

Bowline mediates association of the transcriptional corepressor XGrg-4 with Tbx6 during somitogenesis in Xenopus.

scientific article published on 11 June 2007

Characterization of CXC-type chemokine molecules in early Xenopus laevis development.

scientific article published in January 2013

Chemokine ligand Xenopus CXCLC (XCXCLC) regulates cell movements during early morphogenesis

scientific article published on 22 November 2011

Claudin5 genes encoding tight junction proteins are required for Xenopus heart formation

scientific article published in September 2010

Cloning of noggin gene from hydra and analysis of its functional conservation using Xenopus laevis embryos.

scientific article published in May 2010

Complete mitochondrial genome of "Xenopus tropicalis" Asashima line (Anura: Pipidae), a possible undescribed species

scientific article published on 25 February 2015

Creating frog heart as an organ: in vitro-induced heart functions as a circulatory organ in vivo

scientific article published in January 2010

Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling

scientific article published on 20 October 2008

Development of Ca2+ signaling mechanisms and cell motility in presumptive ectodermal cells during amphibian gastrulation

article

Development of a practical sandwich assay to detect human pluripotent stem cells using cell culture media

Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming

scientific article

Diabetes and stem cell function

scientific article published on 17 May 2015

Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium

scientific article published on 22 September 2008

Directional migration of neuronal PC12 cells in a ratchet wheel shaped microchamber

scientific article published on 01 July 2009

Dullard promotes degradation and dephosphorylation of BMP receptors and is required for neural induction

scientific article published in December 2006

Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo

scientific article published in 2013

Dullard/Ctdnep1 regulates endochondral ossification via suppression of TGF-β signaling

scientific article published in February 2015

Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein

scientific article

Elucidation of the role of activin in organogenesis using a multiple organ induction system with amphibian and mouse undifferentiated cells in vitro

scientific article published on 22 April 2008

Enhanced bone-forming activity of side population cells in the periodontal ligament

scientific article published on 5 February 2013

Enzyme-free passage of human pluripotent stem cells by controlling divalent cations

scientific article published on 11 April 2014

Establishment and culture optimization of a new type of pituitary immortalized cell line

scientific article

Functional Overload Enhances Satellite Cell Properties in Skeletal Muscle

scientific article

Gene expression profile of Xenopus A6 cells cultured under random positioning machine shows downregulation of ion transporter genes and inhibition of dome formation

article

Generation of stomach tissue from mouse embryonic stem cells

scientific article

Genome evolution in the allotetraploid frog Xenopus laevis

scientific article

Global expression of simulated microgravity-responsive genes in Xenopus liver cells.

scientific article

Glycome diagnosis of human induced pluripotent stem cells using lectin microarray

scientific article

Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors

scientific article published in January 2013

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

scientific article

Identification of novel peptides from amphibian (Xenopus tropicalis) skin by direct tissue MALDI-MS analysis

scientific article

Improved efficiency of definitive endoderm induction from human induced pluripotent stem cells in feeder and serum-free culture system.

scientific article

In vitro organogenesis using multipotent cells

scientific article published on February 2010

Induction of differentiation of undifferentiated cells into pancreatic beta cells in vertebrates

scientific article published on January 2012

Induction of intermediate mesoderm by retinoic acid receptor signaling from differentiating mouse embryonic stem cells

scientific article published on January 2013

Induction of neural crest cells from mouse embryonic stem cells in a serum-free monolayer culture

scientific article published on January 2010

Inhibitory Smad proteins promote the differentiation of mouse embryonic stem cells into ependymal-like ciliated cells

scientific article published on 31 August 2010

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism

scientific article published on 26 June 2015

Intensely fluorescent azobenzenes: synthesis, crystal structures, effects of substituents, and application to fluorescent vital stain.

scientific article published in May 2010

Intrinsic ability of adult stem cell in skeletal muscle: an effective and replenishable resource to the establishment of pluripotent stem cells

scientific article published on 02 June 2013

KDEL tagging: a method for generating dominant-negative inhibitors of the secretion of TGF-beta superfamily proteins

scientific article published on 01 January 2012

Lipase member H is a novel secreted protein selectively upregulated in human lung adenocarcinomas and bronchioloalveolar carcinomas

scientific article published on 28 December 2013

Mechanobiology During Vertebrate Organ Development

article

MicroRNAs and epigenetics in adult neurogenesis

scientific article

Microfluidic perfusion culture of human induced pluripotent stem cells under fully defined culture conditions

scientific article

Mitf contributes to melanosome distribution and melanophore dendricity

scientific article

Molecular analyses of Xenopus laevis Mesp-related genes

scientific article published on December 2009

Molecular links among the causative genes for ocular malformation: Otx2 and Sox2 coregulate Rax expression

scholarly article

Monitoring neurodegeneration in diabetes using adult neural stem cells derived from the olfactory bulb

scientific article published on 14 May 2013

N-Cadherin is a prospective cell surface marker of human mesenchymal stem cells that have high ability for cardiomyocyte differentiation

scientific article published on 27 July 2013

N-cadherin is a useful marker for the progenitor of cardiomyocytes differentiated from mouse ES cells in serum-free condition.

scientific article

Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos

scientific article published on 15 January 2012

Nucleoredoxin regulates the Wnt/planar cell polarity pathway in Xenopus

scientific article published on 6 August 2008

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification

scientific article published on 9 July 2014

Pdx1-transfected adipose tissue-derived stem cells differentiate into insulin-producing cells in vivo and reduce hyperglycemia in diabetic mice

scientific article published in January 2010

Physical interaction between Tbx6 and mespb is indispensable for the activation of bowline expression during Xenopus somitogenesis

scientific article

Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin.

scientific article published on 22 January 2016

Podocalyxin is a glycoprotein ligand of the human pluripotent stem cell-specific probe rBC2LCN.

scientific article published on 22 March 2013

Possible linkages between the inner and outer cellular states of human induced pluripotent stem cells

scientific article

Prohibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondria

scientific article

Proteomic analysis of membrane proteins expressed specifically in pluripotent murine embryonic stem cells

scientific article published on 01 January 2009

Rapamycin treatment causes developmental delay, pigmentation defects, and gastrointestinal malformation on Xenopus embryogenesis

scientific article published on 25 December 2010

Recombinant Tol2 transposase with activity in Xenopus embryos

scientific article published on 14 August 2007

Reduction of N-glycolylneuraminic acid in human induced pluripotent stem cells generated or cultured under feeder- and serum-free defined conditions

scientific article

Retinoic acid metabolizing factor xCyp26c is specifically expressed in neuroectoderm and regulates anterior neural patterning in Xenopus laevis

scientific article published in January 2008

Ripply2 is essential for precise somite formation during mouse early development

scientific journal article

Separation with zwitterionic hydrophilic interaction liquid chromatography improves protein identification by matrix-assisted laser desorption/ionization-based proteomic analysis

scientific article

Serum protein isoform profiles indicate the progression of hepatitis C virus-induced liver diseases

scientific article published on 4 February 2013

Structural and quantitative evidence for dynamic glycome shift on production of induced pluripotent stem cells

scientific article

TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner

scientific article

TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates

scientific article published in July 2008

TSC-box is essential for the nuclear localization and antiproliferative effect of XTSC-22

scientific article published on 01 April 2007

Tbx6, Thylacine1, and E47 synergistically activate bowline expression in Xenopus somitogenesis

scientific article published on 23 October 2007

The RNA-binding protein Mex3b has a fine-tuning system for mRNA regulation in early Xenopus development

scientific article

The Xenopus Bowline/Ripply family proteins negatively regulate the transcriptional activity of T-box transcription factors

scientific article

The conserved Rieske oxygenase DAF-36/Neverland is a novel cholesterol-metabolizing enzyme

scientific article

The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth

scientific article published on January 2013

The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus

scientific article published on 6 January 2015

The transcriptional coactivators Yap and TAZ are expressed during early Xenopus development

scientific article published in January 2011

Translocon-associated protein subunit Trap-γ/Ssr3 is required for vascular network formation in the mouse placenta

scientific article published on 11 January 2011

Ubc9 negatively regulates BMP-mediated osteoblastic differentiation in cultured cells

scientific article

Wnt protein-mediated satellite cell conversion in adult and aged mice following voluntary wheel running

scientific article published on 30 January 2014

XRASGRP2 is essential for blood vessel formation during Xenopus development.

scientific article published in January 2010

XSUMO-1 is required for normal mesoderm induction and axis elongation during earlyXenopus development

article

Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis

scientific article published on 22 June 2006

Xenopus furry contributes to release of microRNA gene silencing

scientific article

Xenopus galectin-VIa shows highly specific expression in cement glands and is regulated by canonical Wnt signaling

scientific article published on 10 July 2007

Xnr3 affects brain patterning via cell migration in the neural-epidermal tissue boundary during early Xenopus embryogenesis

scientific article published in January 2013

Zygotic VegT is required for Xenopus paraxial mesoderm formation and is regulated by Nodal signaling and Eomesodermin

scientific article published in January 2010

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells

scientific article

rBC2LCN, a new probe for live cell imaging of human pluripotent stem cells

scientific article published on 12 January 2013

xCOUP-TF-B regulates xCyp26 transcription and modulates retinoic acid signaling for anterior neural patterning in Xenopus

scientific article published in January 2012

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