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List of works by Shirin Arastu-Kapur

A Targeted Multiplexed MALDI MS Assay Platform using Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS) for Monitoring Brain and CSF Biomarkers

scientific article published on 01 August 2020

A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

scientific article published on 29 February 2016

Alzheimer's Disease-Like Neurodegeneration in Porphyromonas gingivalis Infected Neurons with Persistent Expression of Active Gingipains

scientific article published on 05 May 2020

An ab Initio structural model of a nucleoside permease predicts functionally important residues.

scientific article published on 08 May 2009

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors

scientific article published on 24 June 2019

Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay

scientific article published on 12 April 2016

Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit

scientific article

Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion

scientific article

Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.

scientific article

Gingipains Identified in Alzheimer's Disease Brains Differentially Fragment ApoE Proteins

scientific article published in 2021

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

scientific article

Immunoproteasome functions explained by divergence in cleavage specificity and regulation.

scientific article published on 28 November 2017

Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells

scientific article published on December 22, 2011

Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events

scientific article published on May 1, 2011

Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases

scientific article published in June 2006

Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii

scientific article (publication date: July 2006)

Point mutations within the LdNT2 nucleoside transporter gene from Leishmania donovani confer drug resistance and transport deficiency

scientific article published on 24 January 2006

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.

scientific article published on 23 January 2019

Ricolinostat (ACY-1215) induced inhibition of aggresome formation accelerates carfilzomib-induced multiple myeloma cell death

scientific article

Second-site suppression of a nonfunctional mutation within the Leishmania donovani inosine-guanosine transporter

scientific article published on 22 October 2004

Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388

scientific article published on 01 February 2020