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List of works by Sari Pesonen

Ad3-hTERT-E1A, a Fully Serotype 3 Oncolytic Adenovirus, in Patients With Chemotherapy Refractory Cancer ⬇️

scientific article published on August 7, 2012

Adenoviral E4orf3 and E4orf6 proteins, but not E1B55K, increase killing of cancer cells by radiotherapy in vivo

scientific article published on 9 September 2010

Adenoviruses with an αvβ integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases

scientific article

Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity

scientific article

Antiangiogenic arming of an oncolytic vaccinia virus enhances antitumor efficacy in renal cell cancer models

scientific article

Antiviral and antitumor T-cell immunity in patients treated with GM-CSF-coding oncolytic adenovirus

scientific article

Calcium gluconate in phosphate buffered saline increases gene delivery with adenovirus type 5.

scientific article

Cancer, stem cells, and oncolytic viruses

scientific article published on January 2008

Effects of capsid-modified oncolytic adenoviruses and their combinations with gemcitabine or silica gel on pancreatic cancer

scientific article

Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses

scientific article published on 02 June 2009

Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir

scientific article

Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus

scientific article

Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus

scientific article

In vivo and in vitro distribution of type 5 and fiber-modified oncolytic adenoviruses in human blood compartments

scientific article published on 25 January 2011

Incomplete but infectious vaccinia virions are produced in the absence of oncolysis in feline SCCF1 cells

scientific article published on 23 March 2015

Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus ⬇️

scientific article published on July 26, 2011

Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors

scientific article published on 8 August 2011

Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8+ T-cell response, prominent infiltration of CD8+ lymphocytes and Th1 type polarization.

scientific article published on November 2014

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation

scientific article

Multimodal approach using oncolytic adenovirus, cetuximab, chemotherapy and radiotherapy in HNSCC low passage tumour cell cultures

scientific article published on 16 December 2009

Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients ⬇️

scientific article published on 02 April 2013

Oncolytic adenovirus ICOVIR-7 in patients with advanced and refractory solid tumors

scientific article published on 25 May 2010

Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients

scientific article

Oncolytic adenovirus treatment of a patient with refractory neuroblastoma

scientific article

Oncolytic adenoviruses for the treatment of human cancer: focus on translational and clinical data

scientific article

Oncolytic adenoviruses kill breast cancer initiating CD44+CD24-/low cells

scientific article

Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: assessment of safety and immunologic responses in patients

scientific article published on 9 February 2012

Oncolytic virotherapy for treatment of breast cancer, including triple-negative breast cancer

scientific article published on 27 August 2015

Optimized mouse model for the imaging of tumor metastasis upon experimental therapy

scientific article

Phase I study with ONCOS-102 for the treatment of solid tumors - an evaluation of clinical response and exploratory analyses of immune markers.

scientific article published on 15 March 2016

Radiation-induced upregulation of gene expression from adenoviral vectors mediated by DNA damage repair and regulation

scientific article

Replication-Competent Viruses as Cancer Immunotherapeutics: Emerging Clinical Data

scientific article (publication date: August 2015)

Safety and biodistribution of a double-deleted oncolytic vaccinia virus encoding CD40 ligand in laboratory Beagles

scientific article published on 10 December 2014

Safety of glucocorticoids in cancer patients treated with oncolytic adenoviruses

scientific article published on 8 November 2010

Serotype chimeric and fiber-mutated adenovirus Ad5/19p-HIT for targeting renal cancer and untargeting the liver

scientific article

Serotype chimeric oncolytic adenovirus coding for GM-CSF for treatment of sarcoma in rodents and humans

scientific article

Sodium iodide symporter SPECT imaging of a patient treated with oncolytic adenovirus Ad5/3-Δ24-hNIS

scientific article published on April 2011

Switching the fiber knob of oncolytic adenoviruses to avoid neutralizing antibodies in human cancer patients

scientific article published in May 2011

Synergistic anti-tumor efficacy of immunogenic adenovirus ONCOS-102 (Ad5/3-D24-GM-CSF) and standard of care chemotherapy in preclinical mesothelioma model

scientific article published on 10 June 2016

Systemic adenoviral gene delivery to orthotopic murine breast tumors with ablation of coagulation factors, thrombocytes and Kupffer cells

scientific article

Targeted chemotherapy for head and neck cancer with a chimeric oncolytic adenovirus coding for bifunctional suicide protein FCU1.

scientific article published on 13 April 2010

Tissue-specific promoters active in CD44+CD24-/low breast cancer cells

scientific article

Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102 - Support for clinical studies on advanced cancer treatment.

scientific article published on 10 August 2017

Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF.

scientific article

Treatment of melanoma with a serotype 5/3 chimeric oncolytic adenovirus coding for GM-CSF: Results in vitro, in rodents and in humans

scientific article

Verapamil results in increased blood levels of oncolytic adenovirus in treatment of patients with advanced cancer

scientific article published on November 2011

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