List of works - Raija T Sormunen

A mutant collagen XIII alters intestinal expression of immune response genes and predisposes transgenic mice to develop B-cell lymphomas

scientific article

Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection

scientific article published on 17 June 2013

Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention.

scientific article published on 03 September 2015

Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy ⬇️

scientific journal article

Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study

scientific article

Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization

scientific article published in 2012

Characterization of 2-enoyl thioester reductase from mammals. An ortholog of YBR026p/MRF1'p of the yeast mitochondrial fatty acid synthesis type II

scientific article

Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV

scientific article

Common and specific effects of TIE2 mutations causing venous malformations

scientific article

Comparison of polymerase chain reaction methods, in situ hybridization, and enzyme immunoassay for detection of Chlamydia pneumoniae in atherosclerotic carotid plaques.

scientific article published on 04 March 2008

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

scientific article

Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function

scientific article

Distinctive activities of DNA polymerases during human DNA replication

scientific article

Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells

scientific article

Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis

scientific article published on 17 February 2012

Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo

scientific article

Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes

scientific journal article

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury

scientific article

Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney

scientific article

Htd2p/Yhr067p is a yeast 3-hydroxyacyl-ACP dehydratase essential for mitochondrial function and morphology

scientific article

Human saliva-derived exosomes: comparing methods of isolation

scientific article

Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice

scientific journal article

Lack of Collagen XVIII Long Isoforms Affects Kidney Podocytes, whereas the Short Form Is Needed in the Proximal Tubular Basement Membrane ⬇️

scientific article published on December 30, 2010

Localization of a portion of the liver isoform of fatty-acid-binding protein (L-FABP) to peroxisomes

scientific journal article

Loss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null mice

scientific journal article

Lysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling.

scientific article

Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues

scientific article

Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis

scientific article

Mitochondrial function and energy metabolism in umbilical cord blood- and bone marrow-derived mesenchymal stem cells.

scientific article published on 20 July 2011

Muscle-derived collagen XIII regulates maturation of the skeletal neuromuscular junction.

scientific article

Myocardial overexpression of Mecr, a gene of mitochondrial FAS II leads to cardiac dysfunction in mouse

scientific article

Myofibroblast expression in airways and alveoli is affected by smoking and COPD

scientific article published on 11 August 2013

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis

scientific article published on 15 March 2016

Oral mucosal epithelial cells express the membrane anchored mucin MUC1.

scientific article

Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis.

scientific article published on 04 February 2016

Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice

scholarly article

Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane

scientific article

Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I.

scientific article published on 22 May 2015

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition

scientific article

Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line

scientific journal article

Structure-function analysis of enoyl thioester reductase involved in mitochondrial maintenance

scientific article (publication date: 14 March 2003)

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

scientific article published on 18 September 2014

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy

scientific article published on 16 January 2014

Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma

scientific article

UK114, a YjgF/Yer057p/UK114 family protein highly conserved from bacteria to mammals, is localized in rat liver peroxisomes

scientific journal article

Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer

scientific article

Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development

scientific journal article

List of works by Raija T Sormunen

A mutant collagen XIII alters intestinal expression of immune response genes and predisposes transgenic mice to develop B-cell lymphomas

Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection

Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention.

Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy ⬇️

Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study

Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization

Characterization of 2-enoyl thioester reductase from mammals. An ortholog of YBR026p/MRF1'p of the yeast mitochondrial fatty acid synthesis type II

Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV

Common and specific effects of TIE2 mutations causing venous malformations

Comparison of polymerase chain reaction methods, in situ hybridization, and enzyme immunoassay for detection of Chlamydia pneumoniae in atherosclerotic carotid plaques.

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function

Distinctive activities of DNA polymerases during human DNA replication

Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells

Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis

Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo

Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury

Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney

Htd2p/Yhr067p is a yeast 3-hydroxyacyl-ACP dehydratase essential for mitochondrial function and morphology

Human saliva-derived exosomes: comparing methods of isolation

Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice

Lack of Collagen XVIII Long Isoforms Affects Kidney Podocytes, whereas the Short Form Is Needed in the Proximal Tubular Basement Membrane ⬇️

Localization of a portion of the liver isoform of fatty-acid-binding protein (L-FABP) to peroxisomes

Loss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null mice

Lysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling.

Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues

Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis

Mitochondrial function and energy metabolism in umbilical cord blood- and bone marrow-derived mesenchymal stem cells.

Muscle-derived collagen XIII regulates maturation of the skeletal neuromuscular junction.

Myocardial overexpression of Mecr, a gene of mitochondrial FAS II leads to cardiac dysfunction in mouse

Myofibroblast expression in airways and alveoli is affected by smoking and COPD

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis

Oral mucosal epithelial cells express the membrane anchored mucin MUC1.

Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis.

Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice

Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane

Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I.

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition

Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line

Structure-function analysis of enoyl thioester reductase involved in mitochondrial maintenance

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy

Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma

UK114, a YjgF/Yer057p/UK114 family protein highly conserved from bacteria to mammals, is localized in rat liver peroxisomes

Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer

Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development