List of works - Jonathan Spindler

A9 A method to obtain full-length HIV proviral sequences and their sites of integration

Amplifying and quantifying HIV-1 RNA in HIV infected individuals with viral loads below the limit of detection by standard clinical assays

scientific article published on 26 September 2011

Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA.

scientific article published on 13 February 2013

Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo

scientific article published on 8 February 2016

Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors

scientific article published on 27 November 2019

Dimerization of the papillomavirus E2 protein is required for efficient mitotic chromosome association and Brd4 binding

scientific article published on 21 May 2008

Early Emergence and Long-Term Persistence of HIV-Infected T-Cell Clones in Children

scientific article

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus

scientific article published on 01 October 2019

HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy

scientific article published on 30 July 2019

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

scientific article

Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy

scientific article

Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults

scientific article

Multiple sources of contamination in samples from patients reported to have XMRV infection

scientific article (publication date: 2012)

No evidence of HIV replication in children on antiretroviral therapy.

scientific article published on 11 September 2017

PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data

scientific article

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

scientific article

Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART.

scientific article published on 17 April 2017

Therapeutic Vaccination With Dendritic Cells Loaded With Autologous HIV Type 1-Infected Apoptotic Cells

scientific article published on 8 December 2015

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

scientific article

List of works by Jonathan Spindler

A9 A method to obtain full-length HIV proviral sequences and their sites of integration

Amplifying and quantifying HIV-1 RNA in HIV infected individuals with viral loads below the limit of detection by standard clinical assays

Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA.

Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo

Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors

Dimerization of the papillomavirus E2 protein is required for efficient mitotic chromosome association and Brd4 binding

Early Emergence and Long-Term Persistence of HIV-Infected T-Cell Clones in Children

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus

HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy

Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults

Multiple sources of contamination in samples from patients reported to have XMRV infection

No evidence of HIV replication in children on antiretroviral therapy.

PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART.

Therapeutic Vaccination With Dendritic Cells Loaded With Autologous HIV Type 1-Infected Apoptotic Cells

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy