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List of works by Bep Klaver

A conditionally replicating SIV variant that can be used to study the mechanism of protection conferred by live attenuated SIV vaccines.

scientific article published on 3 October 2011

A human immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect

scientific article

A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses

scientific article published on 30 March 2016

An AUG codon upstream of rev and env open reading frames ensures optimal translation of the simian immunodeficiency virus Env protein ⬇️

scientific article published on December 20, 2012

CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA

scientific article published on 18 March 2020

Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine

scientific article

Conditional virus replication as an approach to a safe live attenuated human immunodeficiency virus vaccine

scientific article

Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements.

scientific article

Construction of a doxycycline-dependent simian immunodeficiency virus reveals a nontranscriptional function of tat in viral replication.

scientific article

Functional analysis of the complex trans-activating response element RNA structure in simian immunodeficiency virus

scientific article published on 2 July 2008

HIV-1 tolerates changes in A-count in a small segment of the pol gene

scientific article published on 5 September 2017

Human immunodeficiency virus type 1 splicing at the major splice donor site is controlled by highly conserved RNA sequence and structural elements

scientific article published on 17 September 2015

Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution

scientific article published on 5 June 2008

Replication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against SIVmac239 wild-type challenge in a rhesus macaque model

scientific article

Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine

scientific article (publication date: December 2016)

The HIV-1 Tat protein enhances splicing at the major splice donor site.

scientific article

The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape

article

The genetic stability of a conditional live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution

scientific article published on 20 April 2006

Upstream AUG Codons in the Simian Immunodeficiency Virus SIVmac239 Genome Regulate Rev and Env Protein Translation ⬇️

scientific article published on September 5, 2012

Viral evolution as a tool to improve the tetracycline-regulated gene expression system

scientific article published on 2 February 2004

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