List of works - Odile Sergent

A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells

scientific journal article

A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes.

scientific article published on 29 July 2013

Alkyl galactofuranosides strongly interact with Leishmania donovani membrane and provide antileishmanial activity

scientific article

Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.

scientific article

Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells

scientific article published on 01 August 2007

Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells.

scientific article published on May 2004

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.

scientific article published on 4 March 2010

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.

scientific article published on 13 April 2018

Combination of iron overload plus ethanol and ischemia alone give rise to the same endogenous free iron pool

scientific article published in December 2005

Cooperative interaction of benzo[a]pyrene and ethanol on plasma membrane remodeling is responsible for enhanced oxidative stress and cell death in primary rat hepatocytes.

scientific article published on 26 March 2014

Disturbances in H+ dynamics during environmental carcinogenesis

scientific article published on 20 June 2019

Environmental carcinogenesis and pH homeostasis: Not only a matter of dysregulated metabolism.

scientific article published on 11 January 2017

Ethanol induces oxidative stress in primary rat hepatocytes through the early involvement of lipid raft clustering

scientific article published in January 2008

Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene

scientific article published on 22 September 2018

Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron

scientific article published on 10 August 2020

Glutathione depletion increases nitric oxide-induced oxidative stress in primary rat hepatocyte cultures: involvement of low-molecular-weight iron ⬇️

scientific article published on May 15, 2003

Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis

scientific journal article

Importance of plasma membrane dynamics in chemical-induced carcinogenesis

scientific article published on September 2011

Increased Lipiodol uptake in hepatocellular carcinoma possibly due to increased membrane fluidity by dexamethasone and tamoxifen.

scientific article published on October 2010

Inter-laboratory Validation of Procedures for Measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2′-deoxyguanosine in DNA

scientific article published on 01 March 2002

MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement

scientific article published on 03 October 2020

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide

scientific article published on 27 September 2018

Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae.

scientific article

Membrane fluidity changes are associated with benzo[a]pyrene-induced apoptosis in F258 cells: protection by exogenous cholesterol

scientific article published on December 2006

Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis

scientific article

NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function.

scientific article published on 11 May 2012

On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry

scientific article published on May 2012

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats

scientific article published on 10 September 2019

Physical and chemical modulation of lipid rafts by a dietary n-3 polyunsaturated fatty acid increases ethanol-induced oxidative stress

scientific article published on 01 September 2011

Physical fitness and plasma non-enzymatic antioxidant status at rest and after a wingate test

scientific article published in February 2003

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

scientific article published on 31 July 2019

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

scientific article published on 26 July 2018

Protective Action of Ostreococcus tauri and Phaeodactylum tricornutum Extracts towards Benzo[a]Pyrene-Induced Cytotoxicity in Endothelial Cells

scientific article published on 18 December 2019

Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway.

scientific article published on 15 November 2013

Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport

scientific article published on 7 September 2006

Role for membrane fluidity in ethanol-induced oxidative stress of primary rat hepatocytes

scientific article published on 5 January 2005

Role for membrane remodeling in cell death: implication for health and disease.

scientific article published on 31 December 2012

Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

scientific article

The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.

scientific article published on 04 August 2016

Ximelagatran increases membrane fluidity and changes membrane lipid composition in primary human hepatocytes

scientific article

Zebrafish larva as a reliable model for in vivo assessment of membrane remodeling involvement in the hepatotoxicity of chemical agents.

scientific article

List of works by Odile Sergent

A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells

A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes.

Alkyl galactofuranosides strongly interact with Leishmania donovani membrane and provide antileishmanial activity

Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.

Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells

Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells.

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.

Combination of iron overload plus ethanol and ischemia alone give rise to the same endogenous free iron pool

Cooperative interaction of benzo[a]pyrene and ethanol on plasma membrane remodeling is responsible for enhanced oxidative stress and cell death in primary rat hepatocytes.

Disturbances in H+ dynamics during environmental carcinogenesis

Environmental carcinogenesis and pH homeostasis: Not only a matter of dysregulated metabolism.

Ethanol induces oxidative stress in primary rat hepatocytes through the early involvement of lipid raft clustering

Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene

Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron

Glutathione depletion increases nitric oxide-induced oxidative stress in primary rat hepatocyte cultures: involvement of low-molecular-weight iron ⬇️

Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis

Importance of plasma membrane dynamics in chemical-induced carcinogenesis

Increased Lipiodol uptake in hepatocellular carcinoma possibly due to increased membrane fluidity by dexamethasone and tamoxifen.

Inter-laboratory Validation of Procedures for Measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2′-deoxyguanosine in DNA

MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide

Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae.

Membrane fluidity changes are associated with benzo[a]pyrene-induced apoptosis in F258 cells: protection by exogenous cholesterol

Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis

NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function.

On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats

Physical and chemical modulation of lipid rafts by a dietary n-3 polyunsaturated fatty acid increases ethanol-induced oxidative stress

Physical fitness and plasma non-enzymatic antioxidant status at rest and after a wingate test

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

Protective Action of Ostreococcus tauri and Phaeodactylum tricornutum Extracts towards Benzo[a]Pyrene-Induced Cytotoxicity in Endothelial Cells

Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway.

Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport

Role for membrane fluidity in ethanol-induced oxidative stress of primary rat hepatocytes

Role for membrane remodeling in cell death: implication for health and disease.

Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.

Ximelagatran increases membrane fluidity and changes membrane lipid composition in primary human hepatocytes

Zebrafish larva as a reliable model for in vivo assessment of membrane remodeling involvement in the hepatotoxicity of chemical agents.