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List of works by Edward J Lesnefsky

247

scholarly article by Jennifer Sisler et al., published in September 2013

A New Strategy to Treat Mitochondrial Disease Without Improvement of Mitochondrial Function?

scientific article

A deficiency of apoptosis inducing factor (AIF) in Harlequin mouse heart mitochondria paradoxically reduces ROS generation during ischemia-reperfusion

scientific article

A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection.

scientific article

Acquired deficiency of tafazzin in the adult heart: Impact on mitochondrial function and response to cardiac injury

scientific article

Activation of mitochondrial calpain and increased cardiac injury: beyond AIF release.

scientific article published on 4 December 2015

Activation of mitochondrial μ-calpain increases AIF cleavage in cardiac mitochondria during ischemia-reperfusion

scientific article published on 25 October 2011

Aging-dependent changes in rat heart mitochondrial glutaredoxins--Implications for redox regulation

scientific journal article

Blockade of electron transport at the onset of reperfusion decreases cardiac injury in aged hearts by protecting the inner mitochondrial membrane

scientific article

Blockade of electron transport before ischemia protects mitochondria and decreases myocardial injury during reperfusion in aged rat hearts ⬇️

scientific article published on February 17, 2012

Blockade of electron transport during ischemia preserves bcl-2 and inhibits opening of the mitochondrial permeability transition pore ⬇️

scientific article published on February 25, 2011

Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat

scientific article

Cardiolipin remodeling in the heart

scientific article published on April 2009

Cardioprotection by modulation of mitochondrial respiration during ischemia-reperfusion: role of apoptosis-inducing factor

scientific journal article

Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury

scientific article published on 11 September 2015

Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure

scientific article

Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling.

scientific article

Cytoprotection by the modulation of mitochondrial electron transport chain: The emerging role of mitochondrial STAT3 ⬇️

scientific article published on September 10, 2011

Decreased Cytochrome c Oxidase Subunit VIIa in Aged Rat Heart Mitochondria: Immunocytochemistry ⬇️

scientific article published on October 4, 2011

Dietary inorganic nitrate alleviates doxorubicin cardiotoxicity: mechanisms and implications.

scientific article

Dietary nitrate supplementation protects against Doxorubicin-induced cardiomyopathy by improving mitochondrial function.

scientific article

Effects of Testosterone and Evoked Resistance Exercise after Spinal Cord Injury (TEREX-SCI): study protocol for a randomised controlled trial

scientific article

Electron flow into cytochrome c coupled with reactive oxygen species from the electron transport chain converts cytochrome c to a cardiolipin peroxidase: role during ischemia-reperfusion

scientific article

Fatty acid chain-elongation in perfused rat heart: synthesis of stearoylcarnitine from perfused palmitate

scientific article published on 22 August 2007

Function of mitochondrial Stat3 in cellular respiration

scientific article published on 08 January 2009

Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: implications for cardiac aging

scientific journal article

Inhibition of Apoptosis Signal–Regulating Kinase 1 Reduces Myocardial Ischemia–Reperfusion Injury in the Mouse ⬇️

scientific article published on October 25, 2012

Inhibition of Bcl-2 sensitizes mitochondrial permeability transition pore (MPTP) opening in ischemia-damaged mitochondria

scientific article published on 10 March 2015

Ischemia-reperfusion injury in the aged heart: role of mitochondria

scientific article published on December 2003

Isolating the segment of the mitochondrial electron transport chain responsible for mitochondrial damage during cardiac ischemia

scientific article

Mechanistic Insight of Bivalent Compound 21MO as Potential Neuroprotectant for Alzheimer's Disease

scientific article published on 25 March 2016

Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension ⬇️

scientific article published on November 14, 2012

Mitochondria-localized caveolin in adaptation to cellular stress and injury.

scientific article

Mitochondrial Metabolism in Aging Heart

scientific article

Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727

scientific article published on 09 September 2013

Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species

scientific article

Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion.

scientific article published on 13 September 2006

Modulation of mitochondrial bioenergetics in the isolated Guinea pig beating heart by potassium and lidocaine cardioplegia: implications for cardioprotection.

scientific article published on October 2009

Multi-tasking: nuclear transcription factors with novel roles in the mitochondria ⬇️

scientific article published on June 14, 2012

Oxidative phosphorylation and aging

scientific article published on 10 July 2006

Pivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved Issues

scientific article

Postconditioning Modulates Ischemia-damaged Mitochondria During Reperfusion ⬇️

scientific article published on January 1, 2012

Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential.

scientific article published on 27 February 2009

Potential therapeutic benefits of strategies directed to mitochondria.

scientific article

Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: role of complex I inhibition vs. depolarization of inner mitochondrial membrane

scientific article published on 6 June 2013

Reversible blockade of electron transport with amobarbital at the onset of reperfusion attenuates cardiac injury

scientific article

Sphingosine‐1‐phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration ⬇️

scientific article published on October 19, 2010

Structure of cristae in cardiac mitochondria of aged rat.

scientific article published on 13 November 2006

The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes

scientific article

Therapeutic potential of c-Myc inhibition in the treatment of hypertrophic cardiomyopathy ⬇️

scientific article published on March 1, 2011

Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury

scientific article

What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria?

scientific journal article

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