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List of works by Mariko Kobayashi

A Patient with HCV Infection and a Sustained Virological Response to Direct-acting Antiviral Treatment who Developed Inclusion Body Myositis.

scientific article published on 30 March 2018

A Pilot Study of Thymosin .ALPHA.1 Therapy for Chronic Hepatitis B Patients

scientific article published on October 1, 2003

A matched case-controlled study of 48 and 72 weeks of peginterferon plus ribavirin combination therapy in patients infected with HCV genotype 1b in Japan: amino acid substitutions in HCV core region as predictor of sustained virological response.

scientific article published on March 2009

A nucleotide sequence variation detection system for the core region of hepatitis C virus-1b

scientific article published on 20 December 2006

A pilot study of triple therapy with telaprevir, peginterferon and ribavirin for elderly patients with genotype 1 chronic hepatitis C.

scientific article published on 16 July 2013

Adequate timing of ribavirin reduction in patients with hemolysis during combination therapy of interferon and ribavirin for chronic hepatitis C.

scientific article published in November 2004

Amino Acid Substitutions in the Hepatitis C Virus Core Region Predict Hepatocarcinogenesis Following Eradication of HCV RNA by All-Oral Direct-Acting Antiviral Regimens.

scientific article published on 10 February 2018

Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment

scientific article published on 8 June 2012

Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy

scientific article published on 5 July 2011

Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.

scientific article published in August 2010

Amino acid substitutions in hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by antiviral therapy.

scientific article published in June 2011

Amino acid substitutions in the hepatitis C Virus core region and lipid metabolism are associated with hepatocarcinogenesis in nonresponders to interferon plus ribavirin combination therapy.

scientific article published on 16 August 2012

Amino acid substitutions in the hepatitis C virus core region are the important predictor of hepatocarcinogenesis.

scientific article published in November 2007

Amino acid substitutions in the hepatitis C virus core region of genotype 1b affect very early viral dynamics during treatment with telaprevir, peginterferon, and ribavirin.

scientific article published in April 2010

Amino acid substitutions in the hepatitis C virus core region of genotype 1b are the important predictor of severe insulin resistance in patients without cirrhosis and diabetes mellitus.

scientific article published on June 2009

Analysis of association between circulating miR-122 and histopathological features of nonalcoholic fatty liver disease in patients free of hepatocellular carcinoma.

scientific article

Association of HLA-DR14 with the treatment response in Japanese patients with autoimmune hepatitis

scientific article published on 22 January 2010

Association of IL28B genotype and viral response of hepatitis C virus genotype 2 to interferon plus ribavirin combination therapy.

scientific article published on October 2012

Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy.

scientific article published in November 2005

Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 2a high viral load and virological response to interferon-ribavirin combination therapy.

scientific article published on 5 May 2009

Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.

scientific article published on 23 March 2012

Change of hepatitis B virus genotypes in acute and chronic infections in Japan

scientific article published in November 2008

Changes in viral loads of lamivudine-resistant mutants during entecavir therapy

scientific article published on 15 June 2007

Circulating MicroRNA-122 and Fibrosis Stage Predict Mortality of Japanese Patients With Histopathologically Confirmed NAFLD

scientific article published on 05 November 2019

Circulating microRNA-122 levels are important predictor of hepatitis B virus surface antigen seroclearance

scientific article published on 10 July 2018

Classification of hepatitis B virus genotypes by the PCR-Invader method with genotype-specific probes

scientific article published on 24 August 2006

Clearance of hepatitis B surface antigen during long-term nucleot(s)ide analog treatment in chronic hepatitis B: results from a nine-year longitudinal study

scientific article published on 12 October 2012

Clinical and virological characteristics of untreated patients with chronic hepatitis C who develop serum alanine aminotransferase flare-up

scientific article published on February 2005

Clinical and virological effects of long-term (over 5 years) lamivudine therapy

scientific article published in April 2010

Clinical and virological features of non-breakthrough and severe exacerbation due to lamivudine-resistant hepatitis B virus mutants

scientific article

Clinical characteristics of patients infected with hepatitis B virus genotypes A, B, and C.

scientific article published in January 2002

Clinical features of hepatitis B virus genotype A in Japanese patients.

scientific article published on January 2003

Combination of hepatitis B viral antigens and DNA for prediction of relapse after discontinuation of nucleos(t)ide analogs in patients with chronic hepatitis B.

scientific article published on 22 November 2011

Combination therapy of peginterferon and ribavirin for chronic hepatitis C patients with genotype 1b and low-virus load

scientific article published on 2 March 2009

Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.

scientific article published in June 2011

Comparative quantitative analysis of hepatitis C mutations at amino acids 70 and 91 in the core region by the Q-Invader assay

scientific article published on November 2, 2012

Comparison of interferon and lamivudine treatment in Japanese patients with HBeAg positive chronic hepatitis B

scientific article published on 01 September 2007

Complicated relationships of amino acid substitution in hepatitis C virus core region and IL28B genotype influencing hepatocarcinogenesis

scientific article published on December 2012

Correlation between hepatitis B virus surface antigen level and alpha-fetoprotein in patients free of hepatocellular carcinoma or severe hepatitis

scientific article published on 12 October 2013

Correlation between serum hepatitis B virus core-related antigen and intrahepatic covalently closed circular DNA in chronic hepatitis B patients

scientific article published in January 2009

Correlation of YMDD mutation and breakthrough hepatitis with hepatitis B virus DNA and serum ALT during lamivudine treatment

scientific article published on 25 September 2009

Detection of TERT promoter mutation in serum cell-free DNA using wild-type blocking PCR combined with Sanger sequencing in hepatocellular carcinoma

scientific article published on 26 February 2020

Determinants of response to triple therapy of telaprevir, peginterferon, and ribavirin in previous non-responders infected with HCV genotype 1.

scientific article published on July 2012

Determinants of the clinical outcome of patients with severe acute exacerbation of chronic hepatitis B virus infection.

scientific article published on 29 February 2012

Development of hepatocellular carcinoma in elderly patients with chronic hepatitis C with or without elevated aspartate and alanine aminotransferase levels.

scientific article

Development rate of chronic kidney disease in hepatitis C virus patients with advanced fibrosis after interferon therapy.

scientific article published on 24 August 2011

Diagnosis and Resection Treatment of Triplet Hepatocellular Carcinomas with a non-B non-C Background in a Middle Aged Man over a Period of 6-years

scientific article published on 23 June 2020

Difference in malignancies of chronic liver disease due to non-alcoholic fatty liver disease or hepatitis C in Japanese elderly patients

scientific article published on 19 December 2011

Effect of acute self-limited hepatitis C virus (HCV) superinfection on hepatitis B virus (HBV)-related cirrhosis. Virological features of HBV-HCV dual infection

scientific article published on February 2004

Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C.

scientific article published on 7 February 2013

Effects of a sodium-glucose cotransporter 2 inhibitor in nonalcoholic fatty liver disease complicated by diabetes mellitus: Preliminary prospective study based on serial liver biopsies.

scientific article published on 27 February 2017

Efficacy and anticarcinogenic activity of ribavirin combination therapy for hepatitis C virus-related compensated cirrhosis

scientific article published on 4 October 2012

Efficacy and safety in sitagliptin therapy for diabetes complicated by chronic liver disease caused by hepatitis C virus.

scientific article published on 24 March 2011

Efficacy and safety in sitagliptin therapy for diabetes complicated by non-alcoholic fatty liver disease.

scientific article published on 12 March 2013

Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients with genotype 1b and high virus load

scientific article published in June 2010

Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients with genotype 2 and high virus load

scientific article published in June 2010

Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients.

scientific article published in October 2011

Efficacy and safety of elbasvir plus grazoprevir combination therapy in Japanese patients infected with hepatitis C virus genotype 1b

scientific article published on 23 September 2018

Efficacy in patients with dose reduction in combination therapy of peginterferon and ribavirin for chronic hepatitis C.

scientific article published on 29 February 2008

Efficacy of 6-month interferon therapy in chronic hepatitis B virus infection in Japan.

scientific article published in October 2004

Efficacy of entecavir treatment for lamivudine-resistant hepatitis B over 3 years: histological improvement or entecavir resistance?

scientific article published on 15 February 2009

Efficacy of interferon retreatment after relapse for chronic hepatitis C patients with biochemical response after first interferon therapy

scientific article

Efficacy of interferon therapy in elderly patients with chronic hepatitis C.

scientific article published in January 2006

Efficacy of lamivudine therapy and factors associated with emergence of resistance in chronic hepatitis B virus infection in Japan.

scientific article published in January 2003

Efficacy of lamivudine treatment in Japanese patients with hepatitis B virus-related cirrhosis

scientific article published in November 2004

Efficacy of long-term tenofovir-based rescue therapy in patients with chronic hepatitis B refractory to nucleoside/nucleotide analogs

scientific article published on 3 October 2016

Efficacy of low-dose intermittent interferon-alpha monotherapy in patients infected with hepatitis C virus genotype 1b who were predicted or failed to respond to pegylated interferon plus ribavirin combination therapy

scientific article published on August 2008

Efficacy of prolonged interferon therapy for patients with chronic hepatitis C with HCV-genotype 1b and high virus load

scientific article published in January 2003

Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 1b and high viral load

scientific article published on 21 May 2012

Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 2 and high virus load.

scientific article published on 26 March 2012

Efficacy of switching to entecavir monotherapy in Japanese lamivudine-pretreated patients.

scientific article published in May 2010

Emergence of telaprevir-resistant variants detected by ultra-deep sequencing after triple therapy in patients infected with HCV genotype 1.

scientific article published on June 2013

Evolution of simeprevir-resistant variants in virological non-responders infected with HCV genotype 1b.

scientific article published on April 2015

Evolution of simeprevir-resistant variants over time by ultra-deep sequencing in HCV genotype 1b.

scientific article published on 5 May 2014

Exploratory study on telaprevir given every 8 h at 500 mg or 750 mg with peginterferon-alpha-2b and ribavirin in hepatitis C patients.

scientific article published on 29 November 2012

Extending combination therapy with peginterferon plus ribavirin for genotype 2 chronic hepatitis C virological responders: a pilot study of 7 cases

scientific article published on 3 March 2010

Favorable efficacy of daclatasvir plus asunaprevir in treatment of elderly Japanese patients infected with HCV genotype 1b aged 70 and older.

scientific article

Favorable efficacy of glecaprevir plus pibrentasvir as salvage therapy for HCV failures to prior direct-acting antivirals regimens

scientific article published on 03 September 2018

Favorable efficacy of long-term lamivudine therapy in patients with chronic hepatitis B: an 8-year follow-up study.

scientific article published in April 2005

Fulminant Hepatitis due to de novo Hepatitis B after Cord Blood Transplantation Rescued by Medical Treatment

scientific article published on 15 June 2020

Genetic polymorphism in cyclooxygenase-2 promoter affects hepatic inflammation and fibrosis in patients with chronic hepatitis C.

scientific article published on 28 January 2012

HBcrAg is a predictor of post-treatment recurrence of hepatocellular carcinoma during antiviral therapy

scientific article published on 14 September 2010

HBe antigen loss during lamivudine therapy is not caused by mutations in precore and core promoter genes in patients with chronic hepatitis B.

scientific article published in July 2003

HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy

scientific article published on 10 November 2010

HLA-DP genes polymorphisms associate with hepatitis B surface antigen kinetics and seroclearance during nucleot(s)ide analogue therapy.

scientific article published on 28 August 2014

Hepatocellular carcinoma in noncirrhotic young adult patients with chronic hepatitis B viral infection

scientific article published on 01 June 2004

Hepatocellular carcinoma is the most common liver-related complication in patients with histopathologically-confirmed NAFLD in Japan

scientific article published on 06 November 2018

Hepatocyte steatosis is an important predictor of response to interferon (IFN) monotherapy in Japanese patients infected with HCV genotype 2a: Virological features of IFN-resistant cases with hepatocyte steatosis

scientific article published on April 2005

IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C

scientific article published in July 2011

Impact of Mutations at Amino Acid 70 in Hepatitis C Virus (HCV) Genotype 1b Core Region on Hepatocarcinogenesis following Eradication of HCV RNA.

scientific article

Impact of circulating miR-122 for histological features and hepatocellular carcinoma of nonalcoholic fatty liver disease in Japan

scientific article

Impact of hepatitis B core-related antigen on the incidence of hepatocellular carcinoma in patients treated with nucleos(t)ide analogues

scientific article published on 20 January 2019

Impact of sodium glucose cotransporter 2 inhibitor on histological features and glucose metabolism of non-alcoholic fatty liver disease complicated by diabetes mellitus

scientific article published on 06 February 2019

Impact of virus clearance for the development of hemorrhagic stroke in chronic hepatitis C.

scientific article published on 24 October 2013

Infection with hepatitis B virus genotype A in Tokyo, Japan during 1976 through 2001.

scientific article published in September 2004

Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.

scientific article published on 18 January 2011

Influence of amino-acid polymorphism in the core protein on progression of liver disease in patients infected with hepatitis C virus genotype 1b.

scientific article published in January 2010

Initial- and re-treatment effectiveness of glecaprevir and pibrentasvir for Japanese patients with chronic hepatitis C virus-genotype 1/2/3 infections

scientific article published on 22 March 2019

Interferon therapy for 2 years or longer reduces the incidence of hepatocarcinogenesis in patients with chronic hepatitis C viral infection.

scientific article published on November 2004

Interferon-induced prolonged biochemical response reduces hepatocarcinogenesis in hepatitis C virus infection.

scientific article

Ledipasvir plus sofosbuvir as salvage therapy for HCV genotype 1 failures to prior NS5A inhibitors regimens.

scientific article published on 12 January 2017

Liver Fibrosis and Body Mass Index Predict Hepatocarcinogenesis following Eradication of Hepatitis C Virus RNA by Direct-Acting Antivirals.

scientific article published on October 2016

Long-term continuous entecavir therapy in nucleos(t)ide-naïve chronic hepatitis B patients

scientific article published on 30 May 2012

Long-term effects of peginterferon alfa-2a therapy in Japanese patients with chronic hepatitis B virus infection.

scientific article

Long-term efficacy and emergence of multidrug resistance in patients with lamivudine-refractory chronic hepatitis B treated by combination therapy with adefovir plus lamivudine

scientific article published on 9 August 2013

Long-term efficacy of interferon therapy in patients with chronic hepatitis B virus infection in Japan.

scientific article published on 24 February 2012

Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection

scientific article published on 6 March 2013

Long-term follow-up of interferon monotherapy in 454 consecutive naive patients infected with hepatitis C virus: multi-course interferon therapy may reduce the risk of hepatocellular carcinoma and increase survival

scientific article

Long-term interferon monotherapy reduces the risk of HCV-associated hepatocellular carcinoma

scientific article published on August 2012

Long-term outcome after hepatitis B surface antigen seroclearance in patients with chronic hepatitis B.

scientific article published in January 2006

Long-term outcome after interferon therapy in elderly patients with chronic hepatitis C.

scientific article published in January 2007

Long-term outcome of entecavir treatment of nucleos(t)ide analogue-naïve chronic hepatitis B patients in Japan

scientific article published on 22 August 2018

Long-term presence of HBV in the sera of chronic hepatitis B patients with HBsAg seroclearance.

scientific article published on 26 January 2007

Losartan reduces the onset of type 2 diabetes in hypertensive Japanese patients with chronic hepatitis C.

scientific article published in September 2009

Loss of hepatitis B surface antigen from the serum of patients with chronic hepatitis treated with lamivudine

scientific article published on 01 October 2007

Low rate of YMDD motif mutations in polymerase gene of hepatitis B virus in chronically infected patients not treated with lamivudine.

scientific article published in January 2004

Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: two-year follow-up

scientific article published in April 2008

Low serum level of hepatitis B core-related antigen indicates unlikely reactivation of hepatitis after cessation of lamivudine therapy

scientific article published on 01 August 2007

Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance

scientific article published in February 2006

Natural human interferon beta plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus and a high viral load

scientific article published on 4 November 2008

Non-invasive predictors of prognosis of Asian patients with histopathologically-confirmed lean nonalcoholic fatty liver disease

scientific article published on 04 November 2020

Outcome of All-Oral Direct-Acting Antiviral Regimens on the Rate of Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Genotype 1-Related Chronic Liver Disease

scientific article

PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication

scientific article published on 15 October 2020

Performance of autotaxin as a serum marker for liver fibrosis.

scientific article

Peripheral CD8+/CD25+ lymphocytes may be implicated in hepatocellular injuries in patients with acute-onset autoimmune hepatitis

scientific article published on 01 July 2004

Persistence of acute infection with hepatitis B virus genotype A and treatment in Japan

scientific article published on May 2005

Potential of ultra-highly sensitive immunoassays for hepatitis B surface and core-related antigens in patients with or without development of hepatocellular carcinoma after hepatitis B surface antigen seroclearance

scientific article published on 03 December 2020

Precore wild-type hepatitis B virus with G1896 in the resolution of persistent hepatitis B virus infection.

scientific article published in January 2003

Prediction of response to pegylated interferon and ribavirin in hepatitis C by polymorphisms in the viral core protein and very early dynamics of viremia.

scientific article published on 29 August 2007

Prediction of treatment efficacy and telaprevir-resistant variants after triple therapy in patients infected with hepatitis C virus genotype 1.

scientific article published on 19 June 2013

Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: amino acid substitutions in the core region and low-density lipoprotein cholest

scientific article published on 7 November 2006

Predictive factors of virological non-response to interferon-ribavirin combination therapy for patients infected with hepatitis C virus of genotype 1b and high viral load.

scientific article published in January 2006

Predictors of Insulin Secretion in Japanese Patients with Histopathologically-confirmed Non-alcoholic Fatty Liver Disease

scientific article published on 18 September 2019

Predictors of pruritus in patients with chronic liver disease and usefulness of nalfurafine hydrochloride

scientific article published on 21 March 2017

Predictors of treatment efficacy and liver stiffness changes following therapy with Sofosbuvir plus Ribavirin in patients infected with HCV genotype 2.

scientific article published on 5 January 2018

Predictors of viral kinetics to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b.

scientific article published in November 2007

Prevalence and predictive factors of diabetes in hepatitis virus positive liver cirrhosis with fasting plasma glucose level of <126 mg/dL.

scientific article published on 11 January 2012

Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b.

scientific article

Primary liver carcinoma with sarcomatous changes: Analysis of 10 cases

scientific article published on 08 January 2019

Prognosis and predictors of hepatocellular carcinoma in elderly patients infected with hepatitis B virus.

scientific article published on July 2017

Prolonged hepatitis after acute infection with genotype H hepatitis B virus

scientific article published on 16 November 2007

Prolonged-interferon therapy reduces hepatocarcinogenesis in aged-patients with chronic hepatitis C.

scientific article published in August 2007

Randomized trial of prolonged interferon retreatment for chronic hepatitis C patients with HCV-genotype 1b and high virus load

scientific article published on April 1, 2003

Randomized, controlled trial of natural interferon-alpha therapy for e-antigen-positive chronic hepatitis B patients

scientific article published in June 2002

Rapid and high sensitive detection of Y93H amino acid substitution in HCV NS5A region using the PCR-Invader assay

scientific article published in 2014

Rapid detection of drug-resistant mutations in hepatitis B virus by the PCR-Invader assay

scientific article published on October 13, 2010

Rapid loss of hepatitis C virus genotype 1b from serum in patients receiving a triple treatment with telaprevir (MP-424), pegylated interferon and ribavirin for 12 weeks.

scientific article published on 10 July 2009

Recurrence rates of pruritus after the stop of nalfurafine hydrochloride in chronic liver disease: Preliminary prospective confirmatory trial

scientific article published on 24 April 2018

Relationships between Genetic Variations of PNPLA3, TM6SF2 and Histological Features of Nonalcoholic Fatty Liver Disease in Japan

scientific article published on 27 November 2015

Relationships between serum asunaprevir concentration and alanine aminotransferase elevation during daclatasvir plus asunaprevir for chronic HCV genotype 1b infection.

scientific article published on 20 August 2015

Renal dysfunction and hypophosphatemia during long-term lamivudine plus adefovir dipivoxil therapy in patients with chronic hepatitis B

scientific article published on 26 March 2013

Reply: To PMID 22991257

scientific article published on 11 October 2013

Response to long-term lamivudine treatment in patients infected with hepatitis B virus genotypes A, B, and C.

scientific article

Retreatment efficacy and predictors of ledipasvir plus sofosbuvir to HCV genotype 1 in Japan.

scientific article published on 30 June 2016

Role of NS5A-L31/Y93 Double Wild-type in Failure of Glecaprevir/Pibrentasvir Double Therapy in Two Patients with a History of Direct-acting Antiviral Agent Failure: An Ultra-deep Sequencing Analysis

scientific article published on 07 June 2019

SGLT2 Inhibitor Treatment Outcome in Nonalcoholic Fatty Liver Disease Complicated with Diabetes Mellitus: The Long-term Effects on Clinical Features and Liver Histopathology

scientific article published on 23 May 2020

Selection of a virus strain resistant to entecavir in a nucleoside-naive patient with hepatitis B of genotype H.

scientific article published on 17 April 2007

Serial changes in liver stiffness and controlled attenuation parameter following direct-acting antiviral therapy against hepatitis C virus genotype 1b.

scientific article published on 14 September 2017

Seroclearance rate of hepatitis B surface antigen in 2,112 patients with chronic hepatitis in Japan during long-term follow-up.

scientific article

Serum KL-6 level is elevated in chronic hepatitis C patients with combination therapy of pegylated interferon and ribavirin.

scientific article published on 2 August 2007

Serum levels of gamma-globulin and total bilirubin influence the prevalence of multiple extrahepatic complication in patients with hepatitis C virus infection

scientific article published in January 2003

Severe acute exacerbation of liver disease may reduce or delay emergence of YMDD motif mutants in long-term lamivudine therapy for hepatitis B e antigen-positive chronic hepatitis B.

scientific article published in May 2004

Side effects of combination therapy of peginterferon and ribavirin for chronic hepatitis-C.

scientific article published on 16 November 2007

Significance of serum ribavirin concentration in combination therapy of interferon and ribavirin for chronic hepatitis C.

scientific article published in March 2005

Substitution of amino acid 70 in the hepatitis C virus core region of genotype 1b is an important predictor of elevated alpha-fetoprotein in patients without hepatocellular carcinoma

scientific article published on August 2008

Suitable treatment period in patients with virological response during combination therapy of peginterferon and ribavirin for chronic hepatitis C.

scientific article published on 15 July 2008

Sustained negativity for HCV-RNA over 24 or more months by long-term interferon therapy correlates with eradication of HCV in patients with hepatitis C virus genotype 1b and high viral load

scientific article published on January 2004

Sustained virological response in a patient with chronic hepatitis C treated by monotherapy with the NS3-4A protease inhibitor telaprevir

scientific article published on 25 October 2009

TERT Promoter Mutation in Serum Cell-Free DNA Is a Diagnostic Marker of Primary Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease

scientific article published on 30 September 2020

The Lack of Hepatocyte Steatosis in Adult-onset Type II Citrullinemia Patients as Assessed by 7-year Interval Paired Biopsies

scientific article published on 25 February 2019

The complex association of virus- and host-related factors with HCC rate following HCV clearance

scientific article published on 02 January 2019

The development of chronic kidney disease in Japanese patients with non-alcoholic fatty liver disease.

scientific article published in May 2011

The efficacy and safety of dual oral therapy with daclatasvir and asunaprevir for genotype 1b in Japanese real-life settings

scientific article published on 8 February 2017

The efficacy of 24-week interferon monotherapy for type C liver cirrhosis in Japanese patients with genotype 1b and low virus load

scientific article published on 7 October 2008

The efficacy of interferon-beta monotherapy for elderly patients with type C hepatitis of genotype 2.

scientific article published on 17 August 2009

The efficacy of short-term interferon-beta therapy for chronic hepatitis C patients with low virus load

scientific article published on 3 March 2008

The efficacy of short-term interferon-beta therapy for type C cirrhotic patients with genotype 2a and low virus load.

scientific article published on 16 June 2008

The influence of hepatitis B virus genotype on the development of lamivudine resistance during long-term treatment.

scientific article published on March 2003

Three-dimensional magnetic resonance imaging for stringent diagnosis of advanced fibrosis associated with nonalcoholic steatohepatitis.

scientific article published on 30 January 2013

Usefulness of serum KL-6 for early diagnosis of idiopathic pulmonary fibrosis in patients with hepatitis C virus.

scientific article published on October 2003

Usefulness of the serum KL-6 assay in patients with hepatitis C virus

scientific article

Utility of detection of telaprevir-resistant variants for prediction of efficacy of treatment of hepatitis C virus genotype 1 infection

scientific article

Viral genotypes and response to interferon in patients with acute prolonged hepatitis B virus infection of adulthood in Japan

scientific article published in December 2002

Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir

scientific article

Virological and biochemical features in elderly HCV patients with hepatocellular carcinoma: amino acid substitutions in HCV core region as predictor of mortality after first treatment.

scientific article published on 17 June 2009

Virological and biochemical relapse according to YMDD motif mutant type during long‐term lamivudine monotherapy

scientific article published on December 1, 2003

Virological and biochemical relapse after discontinuation of lamivudine monotherapy for chronic hepatitis B in Japan: comparison with breakthrough hepatitis during long-term treatment

scientific article published in March 2005

Virological differences between patients infected with subtypes Ba and Bj of hepatitis B virus genotype B.

scientific article published in April 2005

Virological outcomes in patients infected chronically with hepatitis B virus genotype A in comparison with genotypes B and C.

scientific article

Virological response and hepatocarcinogenesis in lamivudine-resistant hepatitis B virus genotype C patients treated with lamivudine plus adefovir dipivoxil.

scientific article

YMDD mutants in patients with chronic hepatitis B before treatment are not selected by lamivudine

scientific article