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List of works by Hidenori Ochi

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians

scientific article published on 6 April 2009

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

scientific journal article

A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population

scientific article published on 12 July 2011

A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation

scientific article

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

scientific article published on 16 October 2013

A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.

scientific article published on 31 January 2009

A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.

scientific article published on 18 November 2010

A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing.

scientific article published on 30 July 2013

ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma

scientific article published on 31 March 2016

ADIPOQ polymorphisms are associated with insulin resistance in Japanese women

scientific article published on 31 March 2015

Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice.

scientific article published on 23 September 2009

Achievement of sustained viral response after switching treatment from pegylated interferon α-2b to α-2a and ribavirin in patients with recurrence of hepatitis C virus genotype 1 infection after liver transplantation: a case report.

scientific article published on 25 August 2011

Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C

scientific article published on 13 August 2018

Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy

scientific article published in January 2010

Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection

scientific article

Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

scientific article published on 01 March 2012

Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A.

scientific article published on 4 April 2015

Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits

scientific article published on 01 May 2014

Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease

scientific article

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

scientific article published in October 2015

CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients

article

Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow

scientific article published on 01 March 2003

Chromosome 4q25 Variant rs6817105 Bring Sinus Node Dysfunction and Left Atrial Enlargement

scientific article published in Scientific Reports

Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy

scientific article published on 17 June 2015

Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B.

scientific article published in May 2013

Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice

scientific article published on 15 January 2013

Combination therapies with daclatasvir and asunaprevir on NS3-D168 mutated HCV in human hepatocyte chimeric mice.

scientific article

Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current

scientific article published on January 2016

Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.

scientific article published in June 2011

Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.

scientific article published on 31 May 2010

Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area

article

Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma

scientific article published on 01 September 2018

Correction: Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

scientific article published on 01 January 2019

Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus

scientific article published on 3 April 2017

Development of hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort study.

scientific article

Differences in serum microRNA profiles in hepatitis B and C virus infection.

scientific article published on 5 November 2014

Dual effect of APOBEC3G on Hepatitis B virus

scientific article published on February 2007

Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones

scientific article published on 26 October 2015

Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C.

scientific article published on 25 February 2016

Effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway.

scientific article published on March 2015

Effects of hepatitis B virus infection on the interferon response in immunodeficient human hepatocyte chimeric mice

scientific article published in July 2011

Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection

scientific article published on 25 September 2009

Efficacy and safety of daclatasvir plus asunaprevir therapy for chronic hepatitis C patients with renal dysfunction.

scientific article

Efficacy and safety of edoxaban for treatment of portal vein thrombosis following danaparoid sodium in patients with liver cirrhosis

scientific article published on 24 March 2017

Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study

scientific article published on 16 August 2017

Efficacy and safety of sitagliptin for the treatment of nonalcoholic fatty liver disease with type 2 diabetes mellitus

scientific article published in March 2014

Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis

scientific article

Efficacy of vonoprazan 10 mg compared with 20 mg for the initial treatment in patients with erosive esophagitis: a randomized pilot study

scientific article published on 21 November 2020

Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis

scientific article published on 07 June 2007

Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice

scientific article

Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif.

scientific article published on 18 September 2006

Emergence of drug resistance-associated variants and changes in serum lipid profiles in sofosbuvir plus ledipasvir-treated chronic hepatitis C patients.

scientific article published on 28 June 2017

Empirical Bayes Estimation of Semi-parametric Hierarchical Mixture Models for Unbiased Characterization of Polygenic Disease Architectures.

scientific article

Empirical Bayes estimation of semi-parametric hierarchical mixture models for unbiased characterization of polygenic disease architectures

Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes

scientific article published on 18 September 2018

Eradication of hepatitis C virus genotype 1 after liver transplantation by interferon therapy before surgery: Report of three patients with analysis of interleukin-28 polymorphism, hepatitis C virus core region and interferon-sensitivity determining

scientific article published in November 2011

Erratum to: Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.

scientific article published in January 2018

Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice

scientific article

Evaluation of glycemic variability in chronic liver disease patients with type 2 diabetes mellitus using continuous glucose monitoring

scientific article

G-to-A hypermutation in hepatitis B virus (HBV) and clinical course of patients with chronic HBV infection

scientific article

GJA1 gene polymorphism is a genetic predictor of recurrence following pulmonary vein isolation in patients with paroxysmal atrial fibrillation

scientific article published in 2022

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development

scientific article

Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women.

scientific article

Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese

scientific article published on 7 December 2016

Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.

scientific article

H558R, a common SCN5A polymorphism, modifies the clinical phenotype of Brugada syndrome by modulating DNA methylation of SCN5A promoters

scientific article published on 4 December 2017

HCN4 Gene Polymorphisms Are Associated With Occurrence of Tachycardia-Induced Cardiomyopathy in Patients With Atrial Fibrillation

scientific article published on 01 July 2018

HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy

scientific article published on 10 November 2010

HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study

scientific article

Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle

scientific article

Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse

scientific article

Hepatocellular carcinoma: towards personalized medicine.

scientific article published on 15 March 2012

Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity

scientific article published in January 2003

IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C.

scientific article

IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population

scientific article published on 19 March 2014

IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.

scientific article published on 12 January 2011

IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.

scientific article published on 4 February 2011

IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C

scientific article published in July 2011

IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.

scientific article

ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.

scientific article published on 14 July 2010

ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.

scientific article published on 7 November 2016

Identification of novel HCV deletion mutants in chronic hepatitis C patients

scientific article published on 25 July 2012

Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus

scientific article published on 2 August 2011

Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy

scientific article published in February 2003

Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report.

scientific article

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus

scientific article published on November 2005

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon.

scientific article published on 20 April 2007

Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus.

scientific article

Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus

scientific article

Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C.

scientific article published on 6 May 2014

Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation

scientific article published on September 2012

Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.

scientific article published in September 2011

Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.

scientific article

Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma

scientific article

Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure

scientific article published on 19 June 2018

Liver fibrosis assessment by FibroScan compared with pathological findings of liver resection specimen in hepatitis C infection

scientific article published on 3 September 2016

Long term persistence of NS5A inhibitor-resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy

scientific article

ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo.

scientific article published on 29 November 2010

Maintenance of low inflammation level by the ZFHX3 SNP rs2106261 minor allele contributes to reduced atrial fibrillation recurrence after pulmonary vein isolation

scientific article published in PLoS ONE

NUDT3 rs206936 is associated with body mass index in obese Japanese women

scientific article published on 25 May 2013

Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease

scientific article

Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice

scientific article published on 10 July 2017

Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors

scientific article published on 11 January 2020

Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.

scientific article published in June 2011

Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C.

scientific article published on 21 December 2013

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

scientific article published on 19 September 2010

Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice

scientific article published on 2 April 2018

Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing

scientific article published on 20 September 2016

Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo

scientific article published on 2 August 2011

Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay

scientific article

Real-world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus-infected cirrhosis patients

scientific article published on 11 August 2016

Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

scientific article published on 01 January 2018

Replication study of 15 recently published Loci for body fat distribution in the Japanese population.

scientific article published on 7 December 2012

Risk factors for exacerbation of gastroesophageal varices and portosystemic encephalopathy during treatment with nucleos(t)ide analogs for hepatitis B virus-related cirrhosis

scientific article published on 8 November 2017

Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases

scientific article published on 02 January 2020

Risk factors for the exacerbation of esophageal varices or portosystemic encephalopathy after sustained virological response with IFN therapy for HCV-related compensated cirrhosis

scientific article published on 05 October 2012

Risk stratification of ventricular fibrillation in Brugada syndrome using noninvasive scoring methods

scientific article published on 13 July 2016

Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C.

scientific article published on 8 September 2016

Sample Size for Successful Genome-Wide Association Study of Major Depressive Disorder

scientific article published on 28 June 2018

Ser96Ala genetic variant of the human histidine-rich calcium-binding protein is a genetic predictor of recurrence after catheter ablation in patients with paroxysmal atrial fibrillation

scientific article published on 06 March 2019

Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients

scientific article

Serial profiling of circulating tumor DNA identifies biomarkers for anti-VEGF chemotherapy in mCRC patients

scientific article published on 01 October 2017

Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients.

scientific article

Serum HBV RNA is a predictor of early emergence of the YMDD mutant in patients treated with lamivudine

scientific article published in May 2007

Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.

scientific article

Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse.

scientific article published on 10 July 2012

Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.

scientific article

Successful treatment of an entecavir-resistant hepatitis B virus variant

scientific article published in December 2007

Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease

scientific article published on 13 March 2014

The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients

scientific article

The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma; comparison with interferon-based therapy

scientific article published on 19 November 2018

The risk of transient postprandial oxyhypoglycemia in nonalcoholic fatty liver disease

scientific article published on 28 June 2016

The risks of hepatocellular carcinoma development after HCV eradication are similar between patients treated with peg-interferon plus ribavirin and direct-acting antiviral therapy.

scientific article published on 10 August 2017

Three patients treated with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation: Case report

scientific article published on 6 October 2015

Three patients treated with sofosbuvir plus ledipasvir for recurrent hepatitis C after liver transplantation

scientific article published on 21 February 2017

Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.

scientific article published on 28 November 2011

Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation.

scientific article published on 17 February 2014

Ultradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin.

scientific article

Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology

scientific article published on 28 January 2017

Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases

scientific article published on 02 April 2013

Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers

scientific journal article

[Genetic factors in HLA-DP associated with pathology, therapeutic outcome, and prognosis of chronic hepatitis B]

[HCV persistence and HLA-DQB1]

[Recent progress in the study of genetic variants associated with liver diseases]

scientific article published on 01 September 2013

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