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List of works by Carole Sourbier

Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma

scientific article

Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo

scientific article published on 04 August 2005

Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging ⬇️

scientific article published on October 20, 2011

Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.

scientific article published on 30 November 2016

Detecting the Potential Pharmacological Synergy of Drug Combination by Viability Assays In Vitro

scientific article published in January 2018

Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

scientific article published on 31 January 2017

Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality

scientific article

Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.

scientific article published on 26 May 2009

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).

scientific article

Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI

scientific article published on 12 August 2020

Hyperpolarized [1-13C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

scientific article published on 29 March 2018

Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma ⬇️

scientific article published on October 27, 2010

Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration

scientific article

Met and the microenvironment: new insights for ovarian cancer metastasis

scientific article published on May 2011

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma

scientific article (publication date: 2013)

Metabolism and oxidative stress response pathways in kidney cancer: a tale of chance and necessity

scientific article

Metformin targets Mitochondrial Glycerophosphate Dehydrogenase (mGPDH) to control Rate of Oxidative Phosphorylation and growth of thyroid cancer in vitro and in vivo.

scientific article published on 24 April 2018

Mitochondrial Topoisomerase I is Critical for Mitochondrial Integrity and Cellular Energy Metabolism ⬇️

scientific article published on July 20, 2012

Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

scientific article

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis ⬇️

scientific article published on April 5, 2013

New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease

scientific article published on January 2015

Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments

scientific article published on 07 April 2020

Ovarian cancer: emerging molecular-targeted therapies ⬇️

scientific article published on June 20, 2012

Parathyroid hormone-related protein in human renal cell carcinoma

scientific article

Parathyroid hormone-related protein induces cell survival in human renal cell carcinoma through the PI3K Akt pathway: evidence for a critical role for integrin-linked kinase and nuclear factor kappa B.

scientific article published on 29 April 2007

Plasma HSP90α and liver cancer: a potential biomarker?

scientific article published on 10 October 2017

Preclinical efficacy of dual mTORC1/2 inhibitor AZD8055 in renal cell carcinoma harboring a TFE3 gene fusion

scientific article published on 13 September 2019

Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc

scientific article published on 05 December 2019

Protein kinase D inhibitor CRT0066101 suppresses bladder cancer growth in vitro and xenografts via blockade of the cell cycle at G2/M.

scientific article

Role of the RNA-binding protein HuR in human renal cell carcinoma

scientific article published on 10 March 2010

SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery

scientific article published on January 2016

SnapShot: Renal Cell Carcinoma

scientific article published on 01 April 2016

Synthesis of a stable and orally bioavailable englerin analogue

scientific article published on 8 April 2016

Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer

scientific article

Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma ⬇️

scientific article published on November 1, 2012

Targeting Heat Shock Protein 90 for the Treatment of Malignant Pheochromocytoma ⬇️

scientific article published on February 14, 2013

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers

scientific article published on 10 January 2018

Targeting the nuclear factor-kappaB rescue pathway has promising future in human renal cell carcinoma therapy

scientific article published on December 2007

The HSP90 inhibitor ganetespib synergizes with the MET kinase inhibitor crizotinib in both crizotinib-sensitive and -resistant MET-driven tumor models

scientific article published on 11 October 2013

The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

scientific article

The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy

scientific article published on May 2006

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

scientific article published on 20 July 2015

UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer

scientific article

Uncoupling tumor-stroma interactions in breast cancer patients

scientific article published in June 2017

von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.

scientific article

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