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List of works by Shoichi Takahashi

A case of fulminant hepatic failure caused by hepatitis E virus

scientific article

A first case of hepatic angiosarcoma treated with recombinant interleukin-2.

scientific article published on December 2011

A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing.

scientific article published on 30 July 2013

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

scientific article

Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice.

scientific article published on 23 September 2009

Achievement of sustained viral response after switching treatment from pegylated interferon α-2b to α-2a and ribavirin in patients with recurrence of hepatitis C virus genotype 1 infection after liver transplantation: a case report.

scientific article published on 25 August 2011

Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy

scientific article published in January 2010

Analysis of Post-Progression Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib

scientific article published on 03 September 2020

Attention-getting sexually transmitted diseases: Hepatitis B

scientific article published in November 2007

Balloon-occluded retrograde transvenous obliteration for portal-systemic encephalopathy due to superior mesenteric-caval shunt via the right gonadal vein

scientific article

Beneficial effects of living-donor liver transplantation on esophageal varices

scientific article published on 24 December 2008

Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B.

scientific article published in May 2013

Clinical features and prognosis in patients with hepatocellular carcinoma that developed after hepatitis C virus eradication with interferon therapy

scientific article published on 4 March 2011

Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma

scientific article

Clinical outcome of esophageal varices after hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with major portal vein tumor thrombus

scientific article published on 01 November 2011

Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

scientific article published in December 2013

Clinicopathological features of elderly patients with hepatitis C virus-related hepatocellular carcinoma

scientific article published on 23 July 2008

Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice

scientific article published on 15 January 2013

Combination therapy of oral fluoropyrimidine anticancer drug S-1 and interferon alpha for HCC patients with extrahepatic metastases

scientific article

Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.

scientific article published in June 2011

Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.

scientific article published on 31 May 2010

Comparison of hepatic arterial infusion chemotherapy versus sorafenib monotherapy in patients with advanced hepatocellular carcinoma

scientific article published in September 2015

Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability

scientific article published on 04 February 2020

Complete response to short-term sorafenib treatment alone for hepatocellular carcinoma with bone, lymph node, and peritoneum metastases

scientific article published on 30 April 2016

Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice

scientific article published on 11 January 2013

Development of hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort study.

scientific article

Differences in serum microRNA profiles in hepatitis B and C virus infection.

scientific article published on 5 November 2014

Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B.

scientific article published in January 2010

Dose comparison study of pegylated interferon-alpha-2b plus ribavirin in naïve Japanese patients with hepatitis C virus genotype 2: a randomized clinical trial

scientific article

Dual effect of APOBEC3G on Hepatitis B virus

scientific article published on February 2007

Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders

scientific article published on 30 January 2012

Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo.

scientific article published on May 2007

Effect of prolonged administration of pegylated interferon/ribavirin therapy in genotypes 2a and 2b: propensity score-matched analysis

scientific article published on February 2015

Effects of a 24-week course of interferon-alpha therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma

scientific article

Effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway.

scientific article published on March 2015

Effects of hepatitis B virus infection on the interferon response in immunodeficient human hepatocyte chimeric mice

scientific article published in July 2011

Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection

scientific article published on 25 September 2009

Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study

scientific article published on 16 August 2017

Efficacy of Lusutrombopag for Thrombocytopenia in Patients with Chronic Liver Disease Scheduled to Undergo Invasive Procedures

scientific article published on 21 October 2020

Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma

scientific article

Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study

scientific article published on 14 May 2012

Eicosapentaenoic acid could permit maintenance of the original ribavirin dose in chronic hepatitis C virus patients during the first 12 weeks of combination therapy with pegylated interferon-alpha and ribavirin. A prospective randomized controlled t

scientific article published in January 2007

Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice

scientific article

Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif.

scientific article published on 18 September 2006

Eradication of hepatitis C virus genotype 1 after liver transplantation by interferon therapy before surgery: Report of three patients with analysis of interleukin-28 polymorphism, hepatitis C virus core region and interferon-sensitivity determining

scientific article published in November 2011

Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice

scientific article

Etiology and outcome of acute liver failure: retrospective analysis of 50 patients treated at a single center

scientific article published on 10 July 2008

Evaluation of patients with esophageal varices after endoscopic injection sclerotherapy using multiplanar reconstruction MDCT images

scientific article

Evaluation of portosystemic collaterals by MDCT-MPR imaging for management of hemorrhagic esophageal varices

scientific article published on 14 July 2009

Evaluation of the mRECIST and α-fetoprotein ratio for stratification of the prognosis of advanced-hepatocellular-carcinoma patients treated with sorafenib

scientific article published on 11 August 2012

Evolution of hepatitis C virus quasispecies during ribavirin and interferon-alpha-2b combination therapy and interferon-alpha-2b monotherapy

scientific article published on 21 August 2006

Extracellular water to total body water ratio obtained by bioelectrical impedance analysis determines the dose intensity of lenvatinib for the treatment of patients with advanced hepatocellular carcinoma

scientific article published on 16 December 2020

FDG positron emission tomography/computed tomography for the detection of extrahepatic metastases from hepatocellular carcinoma

scientific article published on 01 February 2009

G to A hypermutation of TT virus.

scientific article published on 6 February 2010

G to A hypermutation of hepatitis B virus.

scientific article published on March 2005

G-to-A hypermutation in hepatitis B virus (HBV) and clinical course of patients with chronic HBV infection

scientific article

HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice.

scientific article published on 10 March 2010

HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study

scientific article

Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification

scientific article published on 01 December 2012

Hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic interferon-α for advanced hepatocellular carcinoma in combination with or without three-dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferio

scientific article published on 16 December 2011

Hepatic carcinosarcoma with heterogeneous carcinomatous and sarcomatous elements: report of a case and review of the literature

scientific article published on 25 February 2010

Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle

scientific article

Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse

scientific article

Hypersensitivity reactions to transcatheter chemoembolization with cisplatin and Lipiodol suspension for unresectable hepatocellular carcinoma

scientific article published on 01 August 2010

IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.

scientific article published on 4 February 2011

IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.

scientific article

Identification of novel HCV deletion mutants in chronic hepatitis C patients

scientific article published on 25 July 2012

Impact of pegylated interferon therapy on outcomes of patients with hepatitis C virus-related hepatocellular carcinoma after curative hepatic resection

scientific article published on 28 June 2011

Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus

scientific article published on 2 August 2011

Importance of serum concentration of adefovir for Lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B.

scientific article

Incidence of microsatellite instability-high hepatocellular carcinoma among Japanese patients and response to pembrolizumab

scientific article published on 23 February 2020

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus

scientific article published on November 2005

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon.

scientific article published on 20 April 2007

Integration of hepatitis B virus DNA and hepatocellular carcinoma

scientific article

Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C.

scientific article published on 6 May 2014

Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation

scientific article published on September 2012

Intra-arterial 5-fluorouracil/interferon combination therapy for advanced hepatocellular carcinoma with or without three-dimensional conformal radiotherapy for portal vein tumor thrombosis

scientific article

Intra-arterial 5-fluorouracil/interferon combination therapy for hepatocellular carcinoma with portal vein tumor thrombosis and extrahepatic metastases

scientific article published on 14 January 2010

Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.

scientific article published in September 2011

Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma

scientific article

Letter of response to the editor

scientific article published on 14 October 2020

Long-term outcome of patients with gastric varices treated by balloon-occluded retrograde transvenous obliteration

scientific article published on 01 May 2014

Low-dose intermittent interferon-alpha therapy for HCV-related liver cirrhosis after curative treatment of hepatocellular carcinoma

scientific article

ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo.

scientific article published on 29 November 2010

Mdm2: A regulator of cell growth and death

scientific article published on January 2003

Multicentric hepatocarcinogenesis at 6 and 13 years after sustained viral response to hepatitis C virus

scientific article

Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients

scientific article

On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy.

scientific article published on 16 April 2014

Percutaneous radiofrequency ablation as first-line treatment for small hepatocellular carcinoma: results and prognostic factors on long-term follow up.

scientific article published on 14 January 2010

Pilot study of systemic combination therapy with S-1, an oral fluoropyrimidine, and cisplatin for hepatocellular carcinoma with extrahepatic metastases.

scientific article

Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor

scientific article published on 17 February 2010

Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.

scientific article published in June 2011

Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C.

scientific article published on 21 December 2013

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

scientific article published on 19 September 2010

Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma.

scientific article

Prolongation of interferon therapy for recurrent hepatitis C after living donor liver transplantation: analysis of predictive factors of sustained virological response, including amino acid sequence of the core and NS5A regions of hepatitis C virus

scientific article published on 22 July 2010

Prophylaxis against recurrence of HBV hepatitis after living-donor liver transplantation.

scientific article

Prospective study of short-term peginterferon-alpha-2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy

scientific article published on 01 April 2008

Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis

scientific article published on 24 October 2019

RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization

scientific article

Randomized trial of high-dose interferon-alpha-2b combined with ribavirin in patients with chronic hepatitis C: Correlation between amino acid substitutions in the core/NS5A region and virological response to interferon therapy

scientific article published on April 2009

Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo

scientific article published on 2 August 2011

Recent trend of clinical features in patients with hepatocellular carcinoma

scientific article published on 13 December 2011

Risk factors for the exacerbation of esophageal varices or portosystemic encephalopathy after sustained virological response with IFN therapy for HCV-related compensated cirrhosis

scientific article published on 05 October 2012

Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma

scientific article published on 19 August 2014

Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C.

scientific article published on 8 September 2016

Safety and feasibility of diet-treated donors with steatotic livers at the initial consultation for living-donor liver transplantation

scientific article published on 01 May 2012

Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients.

scientific article

Serum HBV RNA is a predictor of early emergence of the YMDD mutant in patients treated with lamivudine

scientific article published in May 2007

Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse.

scientific article published on 10 July 2012

Should splenectomy be performed for hepatitis C patients undergoing living-donor liver transplantation?

scientific article published on 01 June 2007

Significant regression of a cavernous hepatic hemangioma to a sclerosed hemangioma over 12 years: a case study

scientific article published in June 2011

Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fluorouracil for the treatment of advanced hepatocellular carcinoma

scientific article published in November 2007

Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients

scientific article published on 08 November 2019

Splenectomy in chronic hepatic disorders: portal vein thrombosis and improvement of liver function

scientific article published on 04 February 2011

Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma

scientific article published in March 2013

Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness.

scientific article published on 17 March 2009

Successful treatment of an entecavir-resistant hepatitis B virus variant

scientific article published in December 2007

Successful treatment of pulmonary metastases associated with advanced hepatocellular carcinoma by systemic 5-fluorouracil combined with interferon-alpha in a hemodialysis patient

scientific article published on 28 October 2008

Surgical treatment for portosystemic encephalopathy in patients with liver cirrhosis: Occlusion of portosystemic shunt in combination with splenectomy

scientific article published on 26 June 2012

Sustained virological response to antiviral therapy improves survival rate in patients with recurrent hepatitis C virus infection after liver transplantation

scientific article published on 5 November 2014

Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: seven cases

scientific article

The first Japanese case of COACH syndrome

scientific article

The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration

scientific article published on 24 August 2007

Transarterial infusion chemotherapy using cisplatin-lipiodol suspension with or without embolization for unresectable hepatocellular carcinoma

scientific article published on 15 May 2009

Transcatheter chemoembolization for unresectable hepatocellular carcinoma and comparison of five staging systems

scientific article published on 28 September 2010

Trends in Hepatic Functional Reserve of Patients with Hepatocellular Carcinoma Treated with Tyrosine Kinase Inhibitors

scientific article published on 24 July 2020

Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation.

scientific article published on 17 February 2014

Ultradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin.

scientific article

Usefulness of combining gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for diagnosing the macroscopic classification of small hepatocellular carcinoma

scientific article published on 3 June 2015

Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases

scientific article published on 02 April 2013

Zoledronic acid delays disease progression of bone metastases from hepatocellular carcinoma

scientific article published on 7 October 2010

[A case of advanced hepatocellular carcinoma with lung, brain and lymph node metastases recurred 8 years after hepatectomy successfully treated by operation, radiation and systemic chemotherapy using S-1/CDDP]

scientific article published on 01 August 2012

[A case of clonorchiasis complicated with the expansion of liver cyst]

scientific article published on 01 March 2013

[Case of double cancer of the liver, cholangiocarcinoma and hepatocellular carcinoma detected in a patient with hepatitis C 13 years after diminution of HCV-RNA by interferon treatment]

scientific article published on 01 May 2009

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