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List of works by Futoshi Akiyama

2013 clinical practice guidelines (The Japanese Breast Cancer Society): history, policy and mission

scientific article published on 24 July 2014

A case of carcinosarcoma of the breast

scientific article published on 01 January 2005

A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization

scientific article published on 19 September 2005

A clinico-pathological study on cancer in sclerosing adenosis

scientific article published on 14 February 2013

A comparison of MR imaging, galactography and ultrasonography in patients with nipple discharge

scientific article

A diagnostic strategy for breast calcifications based on a long-term follow-up of 615 lesions

scientific article published on 19 December 2018

A large-scale gene expression comparison of microdissected, small-sized endometrial cancers with or without hyperplasia matched to same-patient normal tissue.

scientific article published in November 2003

A multicenter phase II trial of neoadjuvant letrozole plus low-dose cyclophosphamide in postmenopausal patients with estrogen receptor-positive breast cancer (JBCRG-07): therapeutic efficacy and clinical implications of circulating endothelial cells

scientific article published on 7 May 2018

A multicenter, phase II study of epirubicin/cyclophosphamide followed by docetaxel and concurrent trastuzumab as primary systemic therapy for HER-2 positive advanced breast cancer (the HER2NAT study)

scientific article published on July 26, 2012

A new molecular-based lymph node staging classification determines the prognosis of breast cancer patients

scientific article

A new reporting form for breast cytology

scientific article

A unique fibrous tumor of the ovary: fibrosarcoma or mitotically active cellular fibroma?

scientific article published on 01 November 2007

Accuracy of magnetic resonance imaging for predicting pathological complete response of breast cancer after neoadjuvant chemotherapy: association with breast cancer subtype

scientific article published on 24 February 2016

Altered lymphatic drainage patterns in re-operative sentinel lymph node biopsy for ipsilateral breast tumor recurrence

scientific article published on 02 September 2019

Alternative use of multiple exons 1 of aromatase gene in cancerous and normal breast tissues from women over the age of 80 years

scientific article published on 10 July 2009

Analysis of ipsilateral breast tumor recurrences after breast-conserving treatment based on the classification of true recurrences and new primary tumors

scientific article published on 01 January 2005

Apocrine metaplasia of breast cancer: clinicopathological features and predicting response

scientific article published on 30 September 2009

Assessment of hormone receptor status in breast cancer

scientific article published in December 2007

Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy

scientific article published in June 2002

Breast cancer associated with mammary hamartoma

scientific article published on 06 August 2009

Breast cancer: individualized diagnosis for tailored treatment

scientific article published on 01 January 2008

Breast pathology slide seminar linked to poster presentations: a new idea to make case presentations in medical conferences more interactive

scientific article published on 01 January 2002

Breast-conserving surgery without radiotherapy in the Cancer Institute Hospital, Tokyo

scientific article published in November 2002

Carcinoma in a solitary intraductal papilloma of the breast

scientific article published on 01 March 2009

Characteristics of adverse events of endocrine therapies among older patients with breast cancer

scientific article published on 07 February 2019

Classification of ipsilateral breast tumor recurrence after breast-conserving therapy: new primary cancer allows a good prognosis

scientific article published on 01 January 2005

Clear Cell Sarcoma of the Neck Which Metastasized to the Mammary Gland

scientific article published on January 22, 2013

Clinical and pathologic features of fibroadenoma of the mastopathic type

scientific article published on 01 January 2006

Clinical importance of androgen receptor in breast cancer patients treated with adjuvant tamoxifen monotherapy

scientific article published on 04 February 2012

Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy

scientific article published on August 2008

Clinical outcomes and prognostic factors in patients with stage II-III breast cancer treated with neoadjuvant chemotherapy followed by surgery and postmastectomy radiation therapy in the modern treatment era

scientific article published on 21 April 2018

Clinicopathologic features of villoglandular papillary adenocarcinoma of the uterine cervix

scientific article published on January 2004

Clinicopathologic study of 53 metaplastic breast carcinomas: their elements and prognostic implications

scientific article published on 12 February 2010

Clinicopathological features of breast cancer patients with internal mammary and/or supraclavicular lymph node recurrence without distant metastasis

scientific article published on 29 September 2020

Clinicopathological significance of 'atypical ductal proliferation' in core needle biopsy of the breast

scientific article published in February 2014

Clinicopathological significance of invasive micropapillary carcinoma component in invasive breast carcinoma

scientific article published on 31 October 2011

Common and discriminative clinicopathological features between breast cancers with pathological complete response or progressive disease in response to neoadjuvant chemotherapy

scientific article published on 14 August 2009

Common peak approach using mass spectrometry data sets for predicting the effects of anticancer drugs on breast cancer

scientific article

Comparative study of monoclonal antibody B72.3 and gross cystic disease fluid protein-15 as markers of apocrine carcinoma of the breast

scientific article

Comparison of different definitions of pathologic complete response in operable breast cancer: a pooled analysis of three prospective neoadjuvant studies of JBCRG.

scientific article

Comparison of dual-color in-situ hybridization and fluorescence in-situ hybridization in HER2 gene amplification in breast cancer

scientific article published on January 12, 2013

Comparison of evaluations for hormone receptors in breast carcinoma using two manual and three automated immunohistochemical assays

scientific article published on 01 March 2007

Correction to: Histological classification of breast tumors in the General Rules for Clinical and Pathological Recording of Breast Cancer (18th edition)

scientific article published on 19 May 2020

Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers

scientific article published in January 2002

Decreased hormonal sensitivity after childbirth rather than the tumor size influences the prognosis of very young breast cancer patients.

scientific article published on 22 July 2015

Detection of occult invasion in ductal carcinoma in situ of the breast with sentinel node metastasis

scientific article published on January 29, 2013

Development of an easy method to test for HER2 in breast cancer using dual-color in situ hybridization

scientific article

Diagnostic mammography and ultrasonography for palpable and nonpalpable breast cancer in women aged 30 to 39 years

scientific article published on 01 January 2007

Diagnostic ultrasonography and mammography for invasive and noninvasive breast cancer in women aged 30 to 39 years

scientific article published on 01 January 2007

Differences in clinical importance of Bcl-2 in breast cancer according to hormone receptors status or adjuvant endocrine therapy.

scientific article published on 15 October 2015

Docetaxel Followed by Fluorouracil/Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy for Patients with Primary Breast Cancer

scientific article published on July 1, 2011

Ductal Carcinoma In Situ That Involves Sclerosing Adenosis: High Frequency of Bilateral Breast Cancer Occurrence

scientific article published on October 17, 2012

Ductal Carcinoma in situ Detected during Prospective MR Imaging Screening of a Woman with a BRCA2 Mutation: The First Case Report in Japan

scientific article published on 13 January 2017

Ductal Carcinoma in situ of the breast in sclerosing adenosis encapsulated by a hamartoma: A case report.

scientific article

Ductal carcinoma in situ and sentinel lymph node metastasis in breast cancer

scientific article

Ductal carcinoma in situ: correlations between high-resolution magnetic resonance imaging and histopathology

Early invasive cervical adenocarcinoma: its potential for nodal metastasis or recurrence

scientific article published on 01 March 2003

Ectopic chromosome around centrosome in metaphase cells as a marker of high-risk human papillomavirus-associated cervical intraepithelial neoplasias.

scientific article

Efficacy and safety of combined trastuzumab and Paclitaxel therapy as a second-line treatment in women with metastatic breast cancer: a single institutional experience

scientific article published on 01 January 2006

Efficacy and safety of trastuzumab as a single agent in heavily pretreated patients with HER-2/neu-overexpressing metastatic breast cancer.

scientific article published on January 2004

Efficacy of fulvestrant 500 mg in Japanese postmenopausal advanced/recurrent breast cancer patients and factors associated with prolonged time-to-treatment failure

scientific article published on 11 November 2015

Endoscopic and histologic findings of intraductal lesions presenting with nipple discharge

scientific article published in September 2006

Endoscopic classification of intraductal lesions and histological diagnosis

scientific article published on 01 January 2002

Estrogen-metabolizing enzymes in breast cancers from women over the age of 80 years

scientific article published on 22 November 2005

Evaluation of HER-2 status in breast carcinoma by fluorescence in situ hybridization and immunohistochemistry

scientific article published on 01 January 2003

Evaluation of interobserver agreement in scoring immunohistochemical results of HER-2/neu (c-erbB-2) expression detected by HercepTest, Nichirei polyclonal antibody, CB11 and TAB250 in breast carcinoma

scientific article published on 01 February 2002

Evaluation of the usefulness of breast CT imaging in delineating tumor extent and guiding surgical management: a prospective multi-institutional study

scientific article published in July 2012

Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray

scientific article published in March 2004

Extension of breast cancer: comparison of CT and MRI.

scientific article published in January 2002

Extensive analysis of signaling pathway molecules in breast cancer: association with clinicopathological characteristics

scientific article published on 15 October 2014

Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.

scientific article

First report of eribulin in combination with pertuzumab and trastuzumab for advanced HER2-positive breast cancer.

scientific article published on 26 June 2017

Five screening-detected breast cancer cases in initially disease-free BRCA1 or BRCA2 mutation carriers

scientific article published on 12 April 2019

Flare-up of dermatomyositis along with recurrence of breast cancer

scientific article published on 01 March 2007

Four types of ipsilateral breast tumor recurrence (IBTR) after breast-conserving surgery: classification of IBTR based on precise pathological examination

scientific article

Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancer

scientific article published on 07 February 2007

Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.

scientific article

General rules for clinical and pathological recording of breast cancer 2005

scientific article published on 01 January 2005

Giant cell tumor of soft tissue of the breast: Case report with H3F3A mutation analysis and review of the literature

scientific article published on 19 November 2019

High levels of DJ-1 protein in nipple fluid of patients with breast cancer

scientific article published on 4 April 2012

High prevalence of HER-2/neu and p53 overexpression in inflammatory breast cancer

scientific article published on 01 January 2006

High-grade breast cancers include both highly sensitive and highly resistant subsets to cytotoxic chemotherapy

scientific article published on 9 February 2010

Histogenesis of metaplastic breast carcinoma and axillary nodal metastases

scientific article published on 01 February 2009

Histological assessment of therapeutic response in breast cancer

scientific article

Histological features of breast cancer, highly sensitive to chemotherapy

scientific article published in January 2007

Histopathological assessment of anastrozole and tamoxifen as preoperative (neoadjuvant) treatment in postmenopausal Japanese women with hormone receptor-positive breast cancer in the PROACT trial

scientific article published on 13 December 2007

Histopathological criteria for assessment of therapeutic response in breast cancer (2007 version)

scientific article published on 01 January 2008

Immunohistochemical evaluation for hormone receptors in breast cancer: a practically useful evaluation system and handling protocol

scientific article published on January 2006

Impact of immunohistological subtypes on the long-term prognosis of patients with metastatic breast cancer

scientific article

Improvement in the prognosis of Japanese breast cancer patients from 1946 to 2001--an institutional review

scientific article published in August 2004

Incidence and prediction of invasive disease and nodal metastasis in preoperatively diagnosed ductal carcinoma in situ

scientific article

Indications and limits of breast conserving treatment

scientific article published in July 2002

Influence of Lymphatic Invasion on Locoregional Recurrence Following Mastectomy: Indication for Postmastectomy Radiotherapy for Breast Cancer Patients With One to Three Positive Nodes

scientific article published on 03 December 2011

Inter-observer agreement among pathologists in grading the pathological response to neoadjuvant chemotherapy in breast cancer

scientific article published on 30 August 2017

Interim analysis of a phase II trial of cyclophosphamide, epirubicin and 5-fluorouracil (CEF) followed by docetaxel as preoperative chemotherapy for early stage breast carcinoma

scientific article published in January 2005

Interobserver variation in the diagnosis of adenoma malignum (minimal deviation adenocarcinoma) of the uterine cervix

scientific article published on 01 July 2003

Intraductal papilloma with bloody discharge from Montgomery's areolar tubercle examined by ductoscopy from the areola

scientific article published on 01 January 2006

Intraoperative Nomograms, Based on One-Step Nucleic Acid Amplification, for Prediction of Non-sentinel Node Metastasis and Four or More Axillary Node Metastases in Breast Cancer Patients with Sentinel Node Metastasis

scientific article published on 05 July 2018

Intraoperative molecular assay for sentinel lymph node metastases in early stage breast cancer: a comparative analysis between one-step nucleic acid amplification whole node assay and routine frozen section histology

scientific article published on 22 March 2011

Invasive carcinoma of the breast accompanied by coarse calcification

scientific article published on 01 July 2009

Ipsilateral breast tumor recurrence (IBTR) after breast-conserving treatment for early breast cancer: risk factors and impact on distant metastases

scientific article published in January 2006

Ipsilateral breast tumor recurrence (IBTR) in patients with operable breast cancer who undergo breast-conserving treatment after receiving neoadjuvant chemotherapy: risk factors of IBTR and validation of the MD Anderson Prognostic Index.

scientific article

Issues in the assessment of the pathologic effect of primary systemic therapy for breast cancer

scientific article

Ki-67 evaluation at the hottest spot predicts clinical outcome of patients with hormone receptor-positive/HER2-negative breast cancer treated with adjuvant tamoxifen monotherapy.

scientific article published on 12 March 2013

Lapatinib-associated mucocutaneous toxicities are clinical predictors of improved progression-free survival in patients with human epidermal growth factor receptor (HER2)-positive advanced breast cancer.

scientific article published in October 2014

Lesion Size on Ultrasonography Predicts Potential Invasion in Ductal Carcinoma in situ Preoperatively Diagnosed by Breast Needle Biopsy

scientific article published in June 2017

Long-term prognoses and outcomes of axillary lymph node recurrence in 2,578 sentinel lymph node-negative patients for whom axillary lymph node dissection was omitted: results from one Japanese hospital

scientific article published on 7 November 2014

Lymphomatoid gastropathy: a distinct clinicopathologic entity of self-limited pseudomalignant NK-cell proliferation

scientific article published on 09 September 2010

MR and US imaging for breast cancer patients who underwent conservation surgery after neoadjuvant chemotherapy: comparison of triple negative breast cancer and other intrinsic subtypes

scientific article published on November 18, 2010

Magnetic resonance-guided focused ultrasound surgery of breast cancer: reliability and effectiveness

scientific article published in July 2006

Malignant phyllodes tumor metastasized to the right ventricle: a case report

scientific article

Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumors

scientific article published on October 1, 2011

Mammary ductoscopy and watchful follow-up substitute microdochectomy in patients with bloody nipple discharge

Microdissection Is Essential for Gene Expression Profiling of Clinically Resected Cancer Tissues

scientific article published on January 1, 2002

Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort

scientific article published on 3 February 2009

Molecular detection of lymph node metastases in breast cancer patients: results of a multicenter trial using the one-step nucleic acid amplification assay

scientific article published on 7 April 2009

More Breast Cancer Metastases Found in Nonsentinel Lymph Nodes Using a Novel Molecular Method

scientific article published on 01 December 2012

Muco-epidermoid carcinoma of the breast

scientific article published on 01 September 2006

Mucocele-like tumor of the breast caused by ductal carcinomain situ: A case report

scientific article published on January 1, 2003

Mutation analysis of the mel-18 gene that shows decreased expression in human breast cancer cell lines

scientific article

Neoadjuvant chemotherapy followed by radical hysterectomy plus postoperative chemotherapy but no radiotherapy for Stage IB2-IIB cervical cancer--irinotecan and platinum chemotherapy

scientific article published on 14 August 2010

Non-sentinel lymph node analysis with one-step nucleic acid amplification in breast cancer patients

scientific article published on 8 May 2015

Oestrogen receptor-beta1 but not oestrogen receptor-betacx is of prognostic value in apocrine carcinoma of the breast

scientific article published in October 2008

One-step nucleic acid amplification for intraoperative detection of lymph node metastasis in breast cancer patients

scientific article published on 01 August 2007

Outcomes of Japanese breast cancer patients treated with pre-operative and post-operative anastrozole or tamoxifen

scientific article published on 13 January 2012

Paclitaxel administered weekly in patients with docetaxel-resistant metastatic breast cancer: a single-center study.

scientific article

Pattern of Tumor Shrinkage during Neoadjuvant Chemotherapy Is Associated with Prognosis in Low-Grade Luminal Early Breast Cancer

scientific article

Performance analysis of the anti-Ki67 antibody clone 30-9 for immunohistochemical staining of breast cancer

scientific article published on 21 May 2020

Phase II study of preoperative sequential FEC and docetaxel predicts of pathological response and disease free survival

scientific article published on 19 September 2007

Postoperative prognosis of node-negative breast cancers predicted by gene-expression profiling on a cDNA microarray of 25,344 genes

scientific article published in January 2005

Predictive Factors and Value of ypN+ after Neoadjuvant Chemotherapy in Clinically Lymph Node-Negative Breast Cancer

scientific article

Predictive implications of nucleoside metabolizing enzymes in premenopausal women with node-positive primary breast cancer who were randomly assigned to receive tamoxifen alone or tamoxifen plus tegafur-uracil as adjuvant therapy

scientific article published on October 2007

Present state of and problems with core needle biopsy for non-palpable breast lesions

scientific article

Prognostic impact and possible pathogenesis of lymph node metastasis in ductal carcinoma in situ of the breast

scientific article published on 24 November 2018

Prognostic significance of histological therapeutic effect in preoperative chemotherapy for breast cancer

scientific article published on 27 November 2015

Prognostic significance of subtype and pathologic response in operable breast cancer; a pooled analysis of prospective neoadjuvant studies of JBCRG.

scientific article published on 14 December 2013

Proportion of estrogen or progesterone receptor expressing cells in breast cancers and response to endocrine therapy.

scientific article published on 29 August 2014

Proposal of a novel method for observing the breast by high-resolution ultrasound imaging: understanding the normal breast structure and its application in an observational method for detecting deviations

scientific article published on November 29, 2011

Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer

scientific article published on September 30, 2010

Radioguided sentinel node detection in breast cancer patients: comparison of 99mTc phytate and 99mTc rhenium colloid efficacy

scientific article published in October 2004

Randomized phase II study of primary systemic chemotherapy and trastuzumab for operable HER2 positive breast cancer.

scientific article

Recommendations for 'adequate evaluation of hormone receptors' a report of the task force of the Japanese Breast Cancer Society

scientific article published in August 2010

Relationships between pathological factors and long-term outcomes in patients enrolled in two prospective randomized controlled trials comparing the efficacy of oral tegafur-uracil with CMF (N·SAS-BC 01 trial and CUBC trial)

scientific article published on 01 December 2020

Reoperative sentinel lymph node biopsy for ipsilateral breast tumor recurrence after previous axillary lymph node dissection: Report of a case

scientific article published on January 26, 2011

Reply: One-step nucleic acid amplification assay also predicts axillary lymph node status in breast cancer patients: further molecular diagnostic evidence.

scientific article

Reproducible and clinically meaningful differential diagnosis is possible between lobular endocervical glandular hyperplasia and 'adenoma malignum' based on common histopathological criteria

scientific article published on 01 July 2005

Reproducible immunohistochemical criteria based on multiple raters' judgments for expression of thymidine phosphorylase in breast cancer tissue

scientific article published in August 2004

Results of survey conducted on perioperative chemotherapy and supportive care in primary breast cancer (JBCRG01)

scientific article published in October 2007

Routine clinical use of the one-step nucleic acid amplification assay for detection of sentinel lymph node metastases in breast cancer patients: results of a multicenter study in Japan

scientific article published on 17 January 2012

Secretory carcinoma of the breast and its histopathological mimics: value of markers for differential diagnosis

scientific article published on 14 August 2013

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Patients With an Initial Diagnosis of Cytology-Proven Lymph Node-Positive Breast Cancer

scientific article published on 11 February 2016

Sentinel node tumour burden quantified based on cytokeratin 19 mRNA copy number predicts non-sentinel node metastases in breast cancer: Molecular whole-node analysis of all removed nodes

scientific article published on December 19, 2012

Skin invasion and prognosis in node negative breast cancer: a retrospective study

scientific article published on 30 January 2008

Small endometrial carcinoma 10 mm or less in diameter: clinicopathologic and histogenetic study of 131 cases for early detection and treatment

scientific article published on 30 September 2013

Spontaneous " healing" of breast cancer

scientific article published on 01 January 2005

Surgical excision without whole breast irradiation for complete resection of ductal carcinoma in situ identified using strict, unified criteria

scientific article

Survival in Cytologically Proven Node-Positive Breast Cancer Patients with Nodal Pathological Complete Response after Neoadjuvant Chemotherapy

scientific article published on 15 September 2020

Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors

scientific article published on 30 September 2015

The cell cycle profiling-risk score based on CDK1 and 2 predicts early recurrence in node-negative, hormone receptor-positive breast cancer treated with endocrine therapy

scientific article published on 10 September 2014

The early onset of peripheral neuropathy might be a robust predictor for time to treatment failure in patients with metastatic breast cancer receiving chemotherapy containing paclitaxel.

scientific article published on 12 September 2017

The prevalence of intrinsic subtypes and prognosis in breast cancer patients of different races

scientific article

The significance of combined CK5/6 and p63 immunohistochemistry in predicting the risks of subsequent carcinoma development in intraductal papilloma of the breast

scientific article published on 8 January 2015

Therapeutic effect of taxanes on metastatic breast cancer of various immunohistochemical subtypes

scientific article published on 25 May 2016

Therapeutic strategies for breast cancer based on histological type

scientific article

Trastuzumab Rechallenge After Lapatinib- and Trastuzumab-Resistant Disease Progression in HER2-Positive Breast Cancer.

scientific article published on 18 June 2015

Triple negative breast cancer: clinicopathological characteristics and treatment strategies.

scientific article

Tumor-infiltrating lymphocytes affect the efficacy of trastuzumab-based treatment in human epidermal growth factor receptor 2-positive breast cancer.

scientific article published on 28 November 2017

Unexpected tumor progression after conization for carcinoma in situ of the uterine cervix

scientific article published on 15 September 2011

Usefulness of second-look ultrasonography using anatomical breast structures as indicators for magnetic resonance imaging-detected breast abnormalities

scientific article published on 12 August 2019

VAB (vacuum-assisted breast biopsy system)

scientific article published on 01 September 2012

Validation study of the UICC TNM classification of malignant tumors, seventh edition, in breast cancer

scientific article published on February 23, 2013

Villoglandular papillary adenocarcinoma of the uterine cervix with bulky lymph node metastases

scientific article published in November 2002

What causes discrepancies in HER2 testing for breast cancer? A Japanese ring study in conjunction with the global standard

scientific article published on December 2008

What is the predictor for invasion in non-palpable breast cancer with microcalcifications?

scientific article published on 01 January 2004

[Evaluation of hormone receptor in breast cancers and the prognosis]

scientific article published on 01 June 2007

[Histological features of breast cancer as predictive factors for chemotherapy]

scientific article published on 01 June 2007