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List of works by Katarzyna Kulig

2-Substituted 4-hydroxybutanamides as potential inhibitors of γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation

scientific article published on 26 June 2013

Analgesic and anticonvulsant activity of new derivatives of 2-substituted 4-hydroxybutanamides in mice

scientific article published on 01 January 2012

Antiarrhythmic and antioxidant activity of novel pyrrolidin-2-one derivatives with adrenolytic properties.

scientific article published on 15 October 2010

Antiarrhythmic and α-Adrenoceptor Antagonistic Properties of Novel Arylpiperazine Derivatives of Pyrrolidin-2-one.

scientific article published on 2 November 2015

Anticonvulsant active inhibitor of GABA transporter subtype 1, tiagabine, with activity in mouse models of anxiety, pain and depression

scientific article published on 21 November 2014

Antidepressant-like activity of the phenylpiperazine pyrrolidin-2-one derivatives in mice.

scientific article published in January 2011

Application of NMR spectroscopy for assignment of the absolute configuration of 8‐tert‐butyl‐2‐hydroxy‐7‐methoxy‐8‐methyl‐9‐oxa‐6‐azaspiro[4.5]dec‐6‐en‐10‐one ⬇️

scientific article published on May 28, 2013

Application of RP-TLC technique for the determination of dissociation constants of 1-substituted pyrrolidin-2-one derivatives

scientific article

Brivaracetam UCB

scientific article

Carisbamate, a new carbamate for the treatment of epilepsy

scientific article published in October 2007

Cebranopadol : a first-in-class potent analgesic agent with agonistic activity at nociceptin/orphanin FQ and opioid receptors

scientific article published on 12 April 2015

Design, synthesis and pharmacological evaluation of alpha-substituted N-benzylamides of gamma-hydroxybutyric acid with potential GABA-ergic activity. Part 6. Search for new anticonvulsant compounds.

scientific article published in March 2007

Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity.

scientific article published on 22 April 2009

Estimation of phospholipophilicity of 1-[3-(arylpiperazin-1-yl)-propyl]-pyrrolidin-2-one derivatives on immobilized artificial membrane stationary phase and its correlation with biological data

scientific article

Estimation of the lipophilicity of antiarrhythmic and antihypertensive active 1-substituted pyrrolidin-2-one and pyrrolidine derivatives

scientific article

Evaluation of anticonvulsant activity of novel pyrrolidin-2-one derivatives

scientific article published on 06 March 2014

Evaluation of anxiolytic-like, anticonvulsant, antidepressant-like and antinociceptive properties of new 2-substituted 4-hydroxybutanamides with affinity for GABA transporters in mice.

scientific article published on 10 July 2013

Experimental drugs for neuropathic pain.

scientific article

GABA transporters as targets for new drugs.

scientific article published on February 2011

Influence of the mobile phase composition on chiral recognition of some pyrrolidin-2-ones in the liquid chromatographic system with polysaccharide stationary phases

scientific article published on 7 October 2007

Investigation into new anticonvulsant derivatives of alpha-substituted N-benzylamides of gamma-hydroxy- and gamma-acetoxybutyric acid. Part 5: search for new anticonvulsant compounds

scientific article

Metabolic benefits of 1-(3-(4-(o-tolyl)piperazin-1-yl)propyl)pyrrolidin-2-one: a non-selective α-adrenoceptor antagonist.

scientific article

New investigational drugs for the treatment of neuropathic pain

scientific article published on 04 June 2014

Novel, highly potent and in vivo active inhibitor of GABA transporter subtype 1 with anticonvulsant, anxiolytic, antidepressant and antinociceptive properties

scientific article published on 19 October 2016

Progress in the Search for New Dopamine Transporter Inhibitors.

scientific article published on 12 August 2015

Pyrrolidin-2-one derivatives may reduce body weight in rats with diet-induced obesity

scientific article published on 16 February 2016

QSAR studies on a number of pyrrolidin-2-one antiarrhythmic arylpiperazinyls

scientific article published on 7 January 2011

Quinoline--a promising fragment in the search for new antimalarials.

scientific article published on April 2014

Search for new potential anticonvulsants with anxiolytic and antidepressant properties among derivatives of 4,4-diphenylpyrrolidin-2-one

scientific article published on 22 September 2016

Structure-Activity Relationship Studies of a Number of α1 -Adrenoceptor Antagonists and Antiarrhythmic Agents

scientific article

Synthesis and development of new 2-substituted 1-[3-(4-arylpiperazin-1-yl)propyl]-pyrrolidin-2-one derivatives with antiarrhythmic, hypotensive, and alpha-adrenolytic activity

scientific article published on 21 September 2005

Synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxypropyl]-pyrrolidin-2-one derivatives with anti-arrhythmic, hypotensive, and alpha-adrenolytic activity

scientific article published on 01 September 2007

Synthesis and pharmacological evaluation of new 1-[3-(4-phenylpiperazin-1-yl)-propyl]- and 1-[3-(4-phenylpiperidine)-propyl]- 3-aryl-3-alkyl-pyrrolidin-2-one derivatives with antiarrhythmic and antihypertensive activity

scientific article published in November 2009

Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents

scientific article published in January 2010

Synthesis and pharmacological properties of new GABA uptake inhibitors.

scientific article published in January 2012

Synthesis of novel N-benzyl substituted piperidine amides of 1H-indole-5-carboxylic acid as potential inhibitors of cholinesterases.

scientific article published in May 2012

Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activity.

scientific article published in March 2002

Synthesis, biological evaluation and structure-activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides.

scientific article published on 12 June 2014

The effect of GABA transporter 1 (GAT1) inhibitor, tiagabine, on scopolamine-induced memory impairments in mice.

scientific article

The role of structure activity relationship studies in the search for new GABA uptake inhibitors

scientific article published on October 2008

The study of the lipophilicity of alpha-(4-phenylpiperazin-1-yl)-gamma-phthalimidobutyramides using chromatographic and computational methods

scientific article

Trends in the development of new drugs for treatment of benign prostatic hyperplasia

scientific article published on January 2006

Use of quantitative structure-enantioselective retention relationship for the liquid chromatography chiral separation prediction of the series of pyrrolidin-2-one compounds

scientific article published on 26 November 2011

Zucapsaicin for the treatment of neuropathic pain.

scientific article

α-Adrenoceptor antagonistic and hypotensive properties of novel arylpiperazine derivatives of pyrrolidin-2-one

scientific article published on 09 March 2015

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