List of works - Carmela Silvestri

Amphibian peptides prevent endotoxemia and bacterial translocation in bile duct-ligated rats

scientific article

Citropin 1.1-treated central venous catheters improve the efficacy of hydrophobic antibiotics in the treatment of experimental staphylococcal catheter-related infection

scientific article

Comparative activities of cecropin A, melittin, and cecropin A-melittin peptide CA(1-7)M(2-9)NH2 against multidrug-resistant nosocomial isolates of Acinetobacter baumannii.

scientific article

Effects of pexiganan alone and combined with betalactams in experimental endotoxic shock.

scientific article published on February 2005

Efficacy of tachyplesin III, colistin, and imipenem against a multiresistant Pseudomonas aeruginosa strain

scientific article published on 2 April 2007

Efficacy of the combination of tachyplesin III and clarithromycin in rat models of Escherichia coli sepsis

scientific article published on 8 September 2008

IB-367 pre-treatment improves the in vivo efficacy of teicoplanin and daptomycin in an animal model of wounds infected with meticillin-resistant Staphylococcus aureus

scientific article published on 27 June 2013

In vitro activities of tachyplesin III against Pseudomonas aeruginosa

scientific article published on 13 January 2007

In vitro activities of the lipopeptides palmitoyl (Pal)-Lys-Lys-NH(2) and Pal-Lys-Lys alone and in combination with antimicrobial agents against multiresistant gram-positive cocci

scientific article published on 23 October 2006

In vitro activity and in vivo animal model efficacy of IB-367 alone and in combination with imipenem and colistin against Gram-negative bacteria

scientific article published on 14 February 2014

In vitro activity and in vivo efficacy of the saponin diosgenyl 2-amino-2-deoxy- -D-glucopyranoside hydrochloride (HSM1) alone and in combination with daptomycin and vancomycin against Gram-positive cocci

scientific article published on 21 April 2011

In vitro activity and killing effect of citropin 1.1 against gram-positive pathogens causing skin and soft tissue infections

scientific article

In vitro activity and killing effect of temporin A on nosocomial isolates of Enterococcus faecalis and interactions with clinically used antibiotics.

scientific article published on 13 January 2005

In vitro activity and killing effect of the synthetic hybrid cecropin A-melittin peptide CA(1-7)M(2-9)NH(2) on methicillin-resistant nosocomial isolates of Staphylococcus aureus and interactions with clinically used antibiotics

scientific article published in July 2004

In vitro activity and killing effect of uperin 3.6 against gram-positive cocci isolated from immunocompromised patients.

scientific article published on September 2005

In vitro activity of MSI-78 alone and in combination with antibiotics against bacteria responsible for bloodstream infections in neutropenic patients

scientific article published in September 2005

In vitro activity of amphibian peptides alone and in combination with antimicrobial agents against multidrug-resistant pathogens isolated from surgical wound infection

scientific article published on 22 April 2005

In vitro activity of aurein 1.2 alone and in combination with antibiotics against gram-positive nosocomial cocci.

scientific article published on 12 January 2007

In vitro activity of citropin 1.1 alone and in combination with clinically used antimicrobial agents against Rhodococcus equi

scientific article published on 27 June 2005

In vitro activity of the histatin derivative P-113 against multidrug-resistant pathogens responsible for pneumonia in immunocompromised patients

scientific article

In vitro activity of the protegrin IB-367 alone and in combination compared with conventional antifungal agents against dermatophytes

scientific article

In vitro activity of the synthetic lipopeptide PAL-Lys-Lys-NH(2) alone and in combination with antifungal agents against clinical isolates of Cryptococcus neoformans

scientific article published on 17 July 2007

In vitro and in vivo effects of sub-MICs of pexiganan and imipenem on Pseudomonas aeruginosa adhesion and biofilm development

scientific article published on December 2013

In vitro susceptibility of dermatophytes to conventional and alternative antifungal agents

scientific article

Lipopeptide Laur-CKK-NH2 dimer preserves daptomycin susceptibility and enhances its activity against Enterococcus faecalis

scientific article

Potential therapeutic role of histatin derivative P-113d in experimental rat models of Pseudomonas aeruginosa sepsis

scientific article

Pretreatment with the protegrin IB-367 affects Gram-positive biofilm and enhances the therapeutic efficacy of linezolid in animal models of central venous catheter infection

scientific article published in November 2007

Protective effect of citropin 1.1 and tazobactam-piperacillin against oxidative damage and lethality in mice models of gram-negative sepsis.

scientific article published on 20 April 2010

Tachyplesin III and granulocyte-colony stimulating factor enhance the efficacy of tazobactam/piperacillin in a neutropenic mouse model of polymicrobial peritonitis

scientific article published on 6 November 2007

Temporin A alone and in combination with imipenem reduces lethality in a mouse model of staphylococcal sepsis

scientific article published on 27 September 2005

Temporin A is effective in MRSA-infected wounds through bactericidal activity and acceleration of wound repair in a murine model

scientific article published on 3 January 2008

Temporin A soaking in combination with intraperitoneal linezolid prevents vascular graft infection in a subcutaneous rat pouch model of infection with Staphylococcus epidermidis with intermediate resistance to glycopeptides

scientific article published on August 2004

The antimicrobial peptide tachyplesin III coated alone and in combination with intraperitoneal piperacillin-tazobactam prevents ureteral stent Pseudomonas infection in a rat subcutaneous pouch model

scientific article published on 7 October 2007

The lipopeptides Pal-Lys-Lys-NH(2) and Pal-Lys-Lys soaking alone and in combination with intraperitoneal vancomycin prevent vascular graft biofilm in a subcutaneous rat pouch model of staphylococcal infection

scientific article published on 31 March 2007

Therapeutic efficacy of the magainin analogue MSI-78 in different intra-abdominal sepsis rat models

scientific article

Vitamin E improves the in vivo efficacy of tigecycline and daptomycin in an animal model of wounds infected with meticillin-resistant Staphylococcus aureus

scientific article published on 11 August 2011

Vitamin E supplementation in old mice induces antimicrobial activity and improves the efficacy of daptomycin in an animal model of wounds infected with methicillin-resistant Staphylococcus aureus

scientific article published on 14 June 2011

List of works by Carmela Silvestri

Amphibian peptides prevent endotoxemia and bacterial translocation in bile duct-ligated rats

Citropin 1.1-treated central venous catheters improve the efficacy of hydrophobic antibiotics in the treatment of experimental staphylococcal catheter-related infection

Comparative activities of cecropin A, melittin, and cecropin A-melittin peptide CA(1-7)M(2-9)NH2 against multidrug-resistant nosocomial isolates of Acinetobacter baumannii.

Effects of pexiganan alone and combined with betalactams in experimental endotoxic shock.

Efficacy of tachyplesin III, colistin, and imipenem against a multiresistant Pseudomonas aeruginosa strain

Efficacy of the combination of tachyplesin III and clarithromycin in rat models of Escherichia coli sepsis

IB-367 pre-treatment improves the in vivo efficacy of teicoplanin and daptomycin in an animal model of wounds infected with meticillin-resistant Staphylococcus aureus

In vitro activities of tachyplesin III against Pseudomonas aeruginosa

In vitro activities of the lipopeptides palmitoyl (Pal)-Lys-Lys-NH(2) and Pal-Lys-Lys alone and in combination with antimicrobial agents against multiresistant gram-positive cocci

In vitro activity and in vivo animal model efficacy of IB-367 alone and in combination with imipenem and colistin against Gram-negative bacteria

In vitro activity and in vivo efficacy of the saponin diosgenyl 2-amino-2-deoxy- -D-glucopyranoside hydrochloride (HSM1) alone and in combination with daptomycin and vancomycin against Gram-positive cocci

In vitro activity and killing effect of citropin 1.1 against gram-positive pathogens causing skin and soft tissue infections

In vitro activity and killing effect of temporin A on nosocomial isolates of Enterococcus faecalis and interactions with clinically used antibiotics.

In vitro activity and killing effect of the synthetic hybrid cecropin A-melittin peptide CA(1-7)M(2-9)NH(2) on methicillin-resistant nosocomial isolates of Staphylococcus aureus and interactions with clinically used antibiotics

In vitro activity and killing effect of uperin 3.6 against gram-positive cocci isolated from immunocompromised patients.

In vitro activity of MSI-78 alone and in combination with antibiotics against bacteria responsible for bloodstream infections in neutropenic patients

In vitro activity of amphibian peptides alone and in combination with antimicrobial agents against multidrug-resistant pathogens isolated from surgical wound infection

In vitro activity of aurein 1.2 alone and in combination with antibiotics against gram-positive nosocomial cocci.

In vitro activity of citropin 1.1 alone and in combination with clinically used antimicrobial agents against Rhodococcus equi

In vitro activity of the histatin derivative P-113 against multidrug-resistant pathogens responsible for pneumonia in immunocompromised patients

In vitro activity of the protegrin IB-367 alone and in combination compared with conventional antifungal agents against dermatophytes

In vitro activity of the synthetic lipopeptide PAL-Lys-Lys-NH(2) alone and in combination with antifungal agents against clinical isolates of Cryptococcus neoformans

In vitro and in vivo effects of sub-MICs of pexiganan and imipenem on Pseudomonas aeruginosa adhesion and biofilm development

In vitro susceptibility of dermatophytes to conventional and alternative antifungal agents

Lipopeptide Laur-CKK-NH2 dimer preserves daptomycin susceptibility and enhances its activity against Enterococcus faecalis

Potential therapeutic role of histatin derivative P-113d in experimental rat models of Pseudomonas aeruginosa sepsis

Pretreatment with the protegrin IB-367 affects Gram-positive biofilm and enhances the therapeutic efficacy of linezolid in animal models of central venous catheter infection

Protective effect of citropin 1.1 and tazobactam-piperacillin against oxidative damage and lethality in mice models of gram-negative sepsis.

Tachyplesin III and granulocyte-colony stimulating factor enhance the efficacy of tazobactam/piperacillin in a neutropenic mouse model of polymicrobial peritonitis

Temporin A alone and in combination with imipenem reduces lethality in a mouse model of staphylococcal sepsis

Temporin A is effective in MRSA-infected wounds through bactericidal activity and acceleration of wound repair in a murine model

Temporin A soaking in combination with intraperitoneal linezolid prevents vascular graft infection in a subcutaneous rat pouch model of infection with Staphylococcus epidermidis with intermediate resistance to glycopeptides

The antimicrobial peptide tachyplesin III coated alone and in combination with intraperitoneal piperacillin-tazobactam prevents ureteral stent Pseudomonas infection in a rat subcutaneous pouch model

The lipopeptides Pal-Lys-Lys-NH(2) and Pal-Lys-Lys soaking alone and in combination with intraperitoneal vancomycin prevent vascular graft biofilm in a subcutaneous rat pouch model of staphylococcal infection

Therapeutic efficacy of the magainin analogue MSI-78 in different intra-abdominal sepsis rat models

Vitamin E improves the in vivo efficacy of tigecycline and daptomycin in an animal model of wounds infected with meticillin-resistant Staphylococcus aureus

Vitamin E supplementation in old mice induces antimicrobial activity and improves the efficacy of daptomycin in an animal model of wounds infected with methicillin-resistant Staphylococcus aureus