Search filters

List of works by Timothy G Pestell

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production

scientific article

CAPER, a novel regulator of human breast cancer progression

scientific article

CCR5 antagonist blocks metastasis of basal breast cancer cells

scientific article

CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis

scientific article

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.

scientific article

Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.

scientific article

Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase

scientific article

Hormonal control of androgen receptor function through SIRT1

scientific article

Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria

scientific article

Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection

scientific article published on December 2011

Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration.

scientific article

Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth

scientific article published on 4 August 2017