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Authors whose works are in public domain in at least one jurisdiction

List of works by Mario Del Tacca

5-fluorouracil administered as a 48-hour chronomodulated infusion in combination with leucovorin and cisplatin: a randomized phase II study in metastatic colorectal cancer.

scientific article published in January 2001

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

scientific article published in May 2008

A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

scientific article published on 7 October 2008

A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.

scientific article published on 25 March 2008

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

scientific article published on 01 October 2006

A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.

scientific article published in March 2004

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

scientific article published in April 2010

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

scientific article published in August 2009

Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study.

scientific article published in December 2001

An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

scientific article published in November 2004

An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

scientific article published on 01 June 1999

Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

scientific article published in October 2002

Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role.

scientific article

Chronic administration of suramin induces neurotoxicity in rats.

scientific article published in November 1997

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

scientific article published on 01 January 1996

Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer.

scientific article published on 21 July 2009

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

scientific article published on July 2013

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

scientific article published on 24 July 2013

Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.

scientific article

Differential affinities of AF-DX 116, atropine and pirenzepine for muscarinic receptors of guinea pig gastric fundus, atria and urinary bladder: might atropine distinguish among muscarinic receptor subtypes?

scientific article published on 01 January 1990

Discordant somatic and germlineVEGF-Agenotype in a cancer patient resistant to paclitaxel/bevacizumab with chemosensitive hepatic metastasis

scientific article published on 01 August 2009

Drug therapeutic failures in emergency department patients. A university hospital experience.

scientific article published in January 2004

Genotype A1/A2 associated with neuroleptic malignant syndrome.

scientific article published in August 2005

Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

scientific article published in June 2005

In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

scientific article published on 16 August 2006

Infusions of fluorouracil and leucovorin: effects of the timing and semi-intermittency of drug delivery

scientific article published on 01 October 1999

Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.

scientific article published on June 2001

Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

scientific article published on 01 January 1999

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

scientific article published on 6 May 2006

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

scientific article published on March 2011

Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

scientific article published on July 2009

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

scientific article

Macrolide antibiotics as antiinflammatory agents: roxithromycin in an unexpected role

scientific article published on 01 January 1993

Metabolism of 6-mercaptopurine in the erythrocytes, liver, and kidney of rats during multiple-dose regimens.

scientific article published in January 1999

Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.

scientific article

Periodontal tissue disposition of azithromycin

scientific article published on 01 December 1997

Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

scientific article

Pharmacokinetic optimisation of the treatment of cancer with high dose zidovudine.

scientific article published on February 1998

Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

scientific article published on May 2002

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

scientific article published on 5 November 2008

Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

scientific article published in October 2002

Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report.

scientific article published on December 2002

Synergistic antiproliferative activity of suramin and alpha 2A-interferon against human colorectal adenocarcinoma cell lines: in vitro studies.

scientific article published on January 1994

The physiopathological aspects of the atrial natriuretic factor

scientific article published on 01 April 1992

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

scientific article published on 01 November 2006

Time-Dependent Pharmacokinetics of 5-Fluorouracil and Association With Treatment Tolerability in the Adjuvant Setting of Colorectal Cancer

scientific article published on 07 March 2011

Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia

scientific article published on 01 August 2000

[A selective antimuscarinic agent: pirenzepine. Review of its pharmacologic and clinical properties]

scientific article published on 01 July 1989

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