List of works by Janine G Einspahr

A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer

scientific article published on 26 January 2010

Accuracy of self-reported smoking status among participants in a chemoprevention trial

scientific article published in April 2004

Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin

scientific article

Analysis of the p53 gene in human precancerous actinic keratosis lesions and squamous cell cancers

scientific article

Association between Cyclooxygenase expression and colorectal adenoma characteristics

scientific article published on July 2003

Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics

scientific article published on August 2006

Chemoprevention of human actinic keratoses by topical 2-(difluoromethyl)-dl-ornithine

scientific article published on 01 December 2000

Chemoprevention of human actinic keratoses by topical DL-alpha-tocopherol

scientific article

Chemoprevention of human skin cancer

scientific article

Chemopreventive efficacy of topical difluoromethylornithine and/or triamcinolone in the treatment of actinic keratoses analyzed by karyometry.

scientific article published in December 2009

Chromatin phenotype karyometry can predict recurrence in papillary urothelial neoplasms of low malignant potential.

scientific article published in January 2007

Comparative in vitro cytotoxicity of cyclophosphamide, its major active metabolites and the new oxazaphosphorine ASTA Z 7557 (INN mafosfamide)

scientific article published on 01 January 1984

Comparison of proliferating cell nuclear antigen versus the more standard measures of rectal mucosal proliferation rates in subjects with a history of colorectal cancer and normal age-matched controls ⬇️

scientific article published on 01 June 1995

Cross-validation of murine UV signal transduction pathways in human skin

scientific article published on 29 January 2008

Cyclooxygenase 2 expression in cervical intraepithelial neoplasia and vulvar cancer

scientific article published on April 2007

Do NSAIDs exert their colon cancer chemoprevention activities through the inhibition of mucosal prostaglandin synthetase?

scientific article published in January 1995

Dose de-escalation chemoprevention trial of alpha-difluoromethylornithine in patients with colon polyps

scientific article

Effect of dipyridamole on fluorodeoxyuridine cytotoxicity in vitro and in cancer patients

scientific article published in January 1989

Effect of subacute ibuprofen dosing on rectal mucosal prostaglandin E2 levels in healthy subjects with a history of resected polyps

scientific article

Effects of Retinoids on Augmentation of Club Cell Secretory Protein

scientific article published on 23 February 2017

Effects of dietary wheat bran fiber on rectal epithelial cell proliferation in patients with resection for colorectal cancers

scientific article published on August 1990

Effects of piroxicam on prostaglandin E2 levels in rectal mucosa of adenomatous polyp patients: a randomized phase IIb trial

scientific article published on 01 December 2000

Evaluation of proliferating cell nuclear antigen as a surrogate end point biomarker in actinic keratosis and adjacent, normal-appearing, and non-sun-exposed human skin samples.

scientific article published on May 1996

Experimental dacarbazine antitumor activity and skin toxicity in relation to light exposure and pharmacologic antidotes.

scientific article

Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction

scientific article (publication date: September 1999)

Expression of p53 protein in actinic keratosis, adjacent, normal-appearing, and non-sun-exposed human skin ⬇️

scientific article published on August 1, 1997

Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression

scientific article published on December 2007

Fecal bile acid concentrations in a subpopulation of the wheat bran fiber colon polyp trial

scientific article published in March 2003

Functional protein pathway activation mapping of the progression of normal skin to squamous cell carcinoma

scientific article

Fyn is a redox sensor involved in solar ultraviolet light-induced signal transduction in skin carcinogenesis

scientific article published on 21 December 2015

Genetic ablation of caspase-7 promotes solar-simulated light-induced mouse skin carcinogenesis: the involvement of keratin-17

scientific article published on 12 August 2015

High Proportion of Nuclear Phenotype Identifies Aggressive Cutaneous Squamous Cell Carcinoma

In vitro cytotoxicity against fresh human tumors and P388 leukemia predicts the differential in vivo activity of a series of anthracene anticancer drugs

scientific article published on February 1991

Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival

scientific article published in July 2003

Inhibition of Akt Enhances the Chemopreventive Effects of Topical Rapamycin in Mouse Skin

scientific article published on 22 January 2016

Inhibitory effects of sodium salicylate and acetylsalicylic acid on UVB-induced mouse skin carcinogenesis

scientific article (publication date: December 2002)

Karyometric analysis of actinic damage in unexposed and sun-exposed skin and in actinic keratoses in untreated individuals

scientific article published on 01 June 2004

Karyometry in rectal mucosa of patients with previous colorectal adenomas

scientific article published on 01 June 2005

Karyometry of nuclei from actinic keratosis and squamous cell cancer of the skin.

scientific article published in December 2003

Karyometry of the colonic mucosa

scientific article published on 01 December 2007

Ki-ras proto-oncogene mutations in sporadic colorectal adenomas: relationship to histologic and clinical characteristics

scientific article published on 01 August 2001

Loss of Inositol Polyphosphate 5-Phosphatase Is an Early Event in Development of Cutaneous Squamous Cell Carcinoma ⬇️

scientific article published on September 28, 2010

MGMT promoter methylation and field defect in sporadic colorectal cancer.

scientific article

Measurement of chemopreventive efficacy in skin biopsies

scientific article published on 01 August 2001

Measurement of prostaglandin E2 in rectal mucosa in human subjects: a method study ⬇️

scientific article published on 01 April 1995

Modulation of biologic endpoints by topical difluoromethylornithine (DFMO), in subjects at high-risk for nonmelanoma skin cancer.

scientific article published in January 2002

New antitumor agents containing the anthracene nucleus

scientific article published on 01 August 1987

Nuclear morphometry identifies a distinct aggressive cellular phenotype in cutaneous squamous cell carcinoma

scientific article

Pharmacokinetics of 13-cis-retinoic acid in patients with advanced cancer

scientific article published on 01 May 1982

Pharmacologic pitfalls in the human tumor clonogenic assay

scientific article published on 01 January 1984

Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer

scientific article published in May 2008

Phase IIB Randomized Study of Topical Difluoromethylornithine and Topical Diclofenac on Sun-Damaged Skin of the Forearm

scientific article published on 28 December 2015

Phase III trial of ursodeoxycholic acid to prevent colorectal adenoma recurrence

scientific article

Physical activity, body mass index, and prostaglandin E2 levels in rectal mucosa

scientific article published on 01 June 1999

Pilot study on the bioactivity of vitamin d in the skin after oral supplementation

scientific article published on 2 April 2015

Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene

scientific article (publication date: 24 June 2003)

Protective role of wheat bran fiber: data from marker trials

scientific article

Protein activation mapping of human sun-protected epidermis after an acute dose of erythemic solar simulated light.

scientific article published on 21 September 2017

Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples

scientific article

Randomized, double-blind, placebo-controlled trial of sulindac in individuals at risk for melanoma: evaluation of potential chemopreventive activity

scientific article

Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis

scientific article

Reliability and validity of a histologic score as a marker for skin cancer chemoprevention studies

scientific article published on 01 October 2003

Reproducibility and expression of skin biomarkers in sun-damaged skin and actinic keratoses

scientific article published on 04 October 2006

Reproducibility of the measurement of colonic proliferation using bromodeoxyuridine across laboratories

scientific article published on May 1996

Resatorvid-based Pharmacological Antagonism of Cutaneous TLR4 Blocks UV-induced NF-κB and AP-1 Signaling in Keratinocytes and Mouse Skin

scientific article published on 10 November 2016

Results of a phase I multiple-dose clinical study of ursodeoxycholic Acid.

scientific article

Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas

scientific article published on 01 October 1999

Safety and efficacy of dose-intensive oral vitamin A in subjects with sun-damaged skin

scientific article published on March 2004

Skin cancer chemoprevention: strategies to save our skin.

scientific article

Statistical analysis of chemopreventive efficacy of vitamin A in sun-exposed, normal skin

scientific article published on 01 August 2002

Surrogate end-point biomarkers as measures of colon cancer risk and their use in cancer chemoprevention trials.

scientific article published on January 1997

Targeting PRPK and TOPK for skin cancer prevention and therapy

scientific article published on 14 June 2018

The effect of wheat bran fiber and calcium supplementation on rectal mucosal proliferation rates in patients with resected adenomatous colorectal polyps

scientific article published on 01 March 1997

Validation of proliferation indices as surrogate endpoint biomarkers.

scientific article published in January 1994

Variation in cyclooxygenase expression levels within the colorectum ⬇️

scientific article published on 01 May 2003

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