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List of works by Steven R. Reiken

A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptors

scientific article published on 3 March 2007

A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium.

scientific article published on 9 June 2011

Acute RyR1 Ca<sup>2+</sup> leak enhances NADH-linked mitochondrial respiratory capacity

scientific article published on 10 December 2021

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

scientific article

Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice

scientific article

Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

scientific article published on 12 May 2003

Bradycardic therapy improves left ventricular function and remodeling in dogs with coronary embolization-induced chronic heart failure

scientific article published on 02 February 2007

Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.

scientific article published on 24 July 2012

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

scientific article

Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

scientific article

Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice

scientific article published on December 2011

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

scientific article

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

scientific article

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

scientific article (publication date: 27 June 2003)

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

scientific article

Intracellular calcium leak as a therapeutic target for RYR1-related myopathies

scientific article published on 31 March 2020

Late Ventilator-Induced Diaphragmatic Dysfunction After Extubation

scientific article published on 01 October 2020

Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice

scientific article

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

scientific article

Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.

scientific article published on 28 May 2012

Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties.

scientific article published in March 2005

Mitochondrial oxidative stress induces leaky ryanodine receptor during mechanical ventilation

scientific article published on 19 November 2019

Modifications of skeletal muscle ryanodine receptor type 1 and exercise intolerance in heart failure.

scientific article

Nonshivering thermogenesis protects against defective calcium handling in muscle

scientific article published on 07 August 2008

Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model

scientific article published on 19 December 2017

Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization

scientific article

PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure

scientific article

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

scientific article

Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice ⬇️

scientific article published on November 22, 2010

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits

scientific article published on 19 June 2017

Progression of heart failure: is protein kinase a hyperphosphorylation of the ryanodine receptor a contributing factor?

scientific article published in January 2002

Protein kinase A and two phosphatases are components of the inositol 1,4,5-trisphosphate receptor macromolecular signaling complex

scientific article published on 7 August 2002

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

scientific article published on 24 October 2002

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

scientific article published on 16 November 2011

Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers

scientific article

Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity

scientific article

Reply from Daniel C. Andersson, Matthew J. Betzenhauser, Steven Reiken, Alisa Umanskaya, Takayuki Shiomi and Andrew R. Marks ⬇️

scientific article published on June 15, 2013

Reply to Eisner et al.: CaMKII phosphorylation of RyR2 increases cardiac contractility.

scientific article published on 21 July 2010

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

scientific article

Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure

scientific article

Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice

scientific article published on 22 November 2010

Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.

scientific article published on August 2011

Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression

scientific article

Short-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions.

scientific article published on 25 November 2014

Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias

scientific journal article

Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor

scientific article published on 15 October 2012

Structure of a mammalian ryanodine receptor

scientific article

The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model

scientific article

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