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List of works by Biyi Chen

Cholesterol is required for maintaining T-tubule integrity and intercellular connections at intercalated discs in cardiomyocytes

scientific article published on 30 May 2016

E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator

scientific article published in Science

In situ single photon confocal imaging of cardiomyocyte T-tubule system from Langendorff-perfused hearts

scientific article published on 6 May 2015

MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress.

scientific article

Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.

scientific article published on 11 February 2014

Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress.

scientific article

Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation.

scientific article

Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.

scientific article published on 27 December 2011

T-tubule remodeling during transition from hypertrophy to heart failure.

scientific article published on 24 June 2010

The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice.

scientific article

The mitochondrial uniporter controls fight or flight heart rate increases.

scientific article

The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias

scientific article

Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca2+]i in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity

scientific article published on 4 January 2018

β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction.

scientific article