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List of works by Giovanna M Ledda-Columbano

Aging does not reduce the hepatocyte proliferative response of mice to the primary mitogen TCPOBOP.

scientific article published in October 2004

Alpha-lipoic acid promotes the growth of rat hepatic pre-neoplastic lesions in the choline-deficient model.

scientific article published on 24 September 2007

Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis

scientific article published on 03 October 2015

Different effects of the liver mitogens triiodo-thyronine and ciprofibrate on the development of rat hepatocellular carcinoma

scientific article published on January 2003

Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3.

scientific article published on 25 February 2011

Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia

scientific article published in November 2005

Induction of autophagy promotes the growth of early preneoplastic rat liver nodules

scientific article published on 31 December 2015

Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats

scientific article

Loss of cyclin D1 does not inhibit the proliferative response of mouse liver to mitogenic stimuli.

scientific article published in November 2002

Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis

scientific article published on 7 April 2016

MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC).

scientific article published on 18 November 2013

Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis.

scientific article published on 22 April 2015

Potential utility of xenobiotic mitogens in the context of liver regeneration in the elderly and living-related transplantation.

scientific article published on 11 February 2008

Progenitor-derived hepatocellular carcinoma model in the rat.

scientific article

TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells.

scientific article published on July 2010

The Thyromimetic KB2115 (Eprotirome) Induces Rat Hepatocyte Proliferation.

scientific article

The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival

scientific article

The peroxisome proliferator BR931 kills FaO cells by p53-dependent apoptosis.

scientific article published on June 2004

The thyroid hormone receptor-beta agonist GC-1 induces cell proliferation in rat liver and pancreas

scientific journal article

Thyroid hormone (T3) and TRbeta agonist GC-1 inhibit/reverse nonalcoholic fatty liver in rats.

scientific article published on 23 April 2008

Thyroid hormone induces cyclin D1 nuclear translocation and DNA synthesis in adult rat cardiomyocytes

scientific article published on January 2006

Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming

scientific article published on 15 January 2020

Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype.

scientific article

Timed regulation of P-element-induced wimpy testis-interacting RNA expression during rat liver regeneration

scientific article published on July 2014

YAP activation is an early event and a potential therapeutic target in liver cancer development.

scientific article

Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice.

scientific article

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