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List of works by Elisabetta Melloni

C-Reactive protein downregulates TRAIL expression in human peripheral monocytes via an Egr-1-dependent pathway

scientific article published on 6 March 2013

Combined treatment of CpG-oligodeoxynucleotide with Nutlin-3 induces strong immune stimulation coupled to cytotoxicity in B-chronic lymphocytic leukemic (B-CLL) cells

scientific article published on 12 November 2007

Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye.

scientific article published on January 2009

Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets

scientific article

Dasatinib plus Nutlin-3 shows synergistic antileukemic activity in both p53 wild-type and p53 mutated B chronic lymphocytic leukemias by inhibiting the Akt pathway

scientific article published on 24 November 2010

Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70

article

Functional expression of TRAIL and TRAIL-R2 during human megakaryocytic development

article

Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma xenografts

scientific article

Inverse correlation between circulating levels of TNF-related apoptosis-inducing ligand and 17β-estradiol

scientific article

MCL1 down-regulation plays a critical role in mediating the higher anti-leukaemic activity of the multi-kinase inhibitor Sorafenib with respect to Dasatinib.

scientific article published on 8 February 2012

Merkel-cell polyomavirus (MCPyV) is rarely associated to B-chronic lymphocytic leukemia (1 out of 50) samples and occurs late in the natural history of the disease.

scientific article published on 7 September 2012

Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism

scientific article

Perifosine plus nutlin-3 combination shows a synergistic anti-leukaemic activity

scientific article published in December 2009

Release of a specific set of proinflammatory adipokines by differentiating 3T3-L1 cells

scientific article published on January 2013

Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells

scientific article published in April 2006

Sorafenib inhibits in vitro osteoclastogenesis by down-modulating Mcl-1.

scientific article

Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells

scientific article published on May 2007

TNF-related apoptosis-inducing ligand (TRAIL) blocks osteoclastic differentiation induced by RANKL plus M-CSF.

scientific article published on 22 June 2004

TRAIL regulates normal erythroid maturation through an ERK-dependent pathway

scientific article published on 11 September 2003

The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts

scientific article published on October 2007

The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40.

scientific article published on 25 April 2013

The negative prognostic value of TRAIL overexpression in oral squamous cell carcinomas does not preclude the potential therapeutic use of recombinant TRAIL

The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells

scientific article published on 9 March 2010

The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status

scientific article

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells

scientific article published in August 2003

Tumor necrosis factor-related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway

scientific article published on October 2002

Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells.

scientific article published on 4 September 2008

miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells

scientific article

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