List of works - Scott Southwood

A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules

scientific article

A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population

scientific article published on 8 February 2013

Class I molecules with similar peptide-binding specificities are the result of both common ancestry and convergent evolution

scientific article published on 14 February 2003

Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires

scientific article published on 8 July 2005

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

scientific article

Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A102601 and Mamu-B08301 reveals HLA-A2 and HLA-A3 supertypic specificities

scientific article

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

scientific article

HLA-A0201, HLA-A1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products

scientific article published in October 2005

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

scientific article

Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus

scientific article published on 10 March 2010

Identification of protective Lassa virus epitopes that are restricted by HLA-A2.

scientific article

Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1082:01 (Mane A0301) ⬇️

scientific article published on January 26, 2012

Improved immunogenicity of an immunodominant epitope of the HER-2/neu protooncogene by alterations of MHC contact residues

scientific article published on March 2004

Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture

scientific article

Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles

scientific article

Predicting population coverage of T-cell epitope-based diagnostics and vaccines

scientific article published on 17 March 2006

Rationally engineered therapeutic proteins with reduced immunogenicity

scientific article published in March 2005

Simultaneous prediction of binding capacity for multiple molecules of the HLA B44 supertype

scientific article published in December 2003

T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts

scientific article

The HLA molecules DQA10501/B10201 and DQA10301/B10302 share an extensive overlap in peptide binding specificity

scientific article (publication date: November 2002)

The most common Chinese rhesus macaque MHC class I molecule shares peptide binding repertoire with the HLA-B7 supertype

scientific article

List of works by Scott Southwood

A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules

A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population

Class I molecules with similar peptide-binding specificities are the result of both common ancestry and convergent evolution

Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus

Identification of protective Lassa virus epitopes that are restricted by HLA-A2.

Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1*082:01 (Mane A*0301) ⬇️

Improved immunogenicity of an immunodominant epitope of the HER-2/neu protooncogene by alterations of MHC contact residues

Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture

Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles

Predicting population coverage of T-cell epitope-based diagnostics and vaccines

Rationally engineered therapeutic proteins with reduced immunogenicity

Simultaneous prediction of binding capacity for multiple molecules of the HLA B44 supertype

T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts

The HLA molecules DQA1*0501/B1*0201 and DQA1*0301/B1*0302 share an extensive overlap in peptide binding specificity

The most common Chinese rhesus macaque MHC class I molecule shares peptide binding repertoire with the HLA-B7 supertype

Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A102601 and Mamu-B08301 reveals HLA-A2 and HLA-A3 supertypic specificities

HLA-A0201, HLA-A1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products

Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1082:01 (Mane A0301) ⬇️

The HLA molecules DQA10501/B10201 and DQA10301/B10302 share an extensive overlap in peptide binding specificity