Search filters

List of works by Hideo Orimo

Altered TNSALP expression and phosphate regulation contribute to reduced mineralization in mice lacking androgen receptor.

scientific article

Associations between serum bone-specific alkaline phosphatase activity, biochemical parameters, and functional polymorphisms of the tissue-nonspecific alkaline phosphatase gene in a Japanese population

scientific article

Bone formation following transplantation of genetically modified primary bone marrow stromal cells

Characterization of the mutant (A115V) tissue-nonspecific alkaline phosphatase gene from adult-type hypophosphatasia

scientific article published in February 2005

Development of a novel chronic kidney disease mouse model to evaluate the progression of hyperphosphatemia and associated mineral bone disease

scientific article

Diversity of progesterone action on lipopolysaccharide-induced expression changes in cultured human cervical fibroblasts according to inflammation and treatment timing

scientific article

Effects of phosphates on the expression of tissue-nonspecific alkaline phosphatase gene and phosphate-regulating genes in short-term cultures of human osteosarcoma cell lines

scientific article published on January 2006

Function of mutant (G1144A) tissue-nonspecific ALP gene from hypophosphatasia

scientific article published in November 2002

Functional analysis of the single nucleotide polymorphism (787T>C) in the tissue-nonspecific alkaline phosphatase gene associated with BMD.

scientific article

Functional assay of the mutant tissue-nonspecific alkaline phosphatase gene using U2OS osteoblast-like cells

scientific article

Genetic diagnosis of Werdnig-Hoffmann disease: a problem for application to prenatal diagnosis.

scientific article

Genetic screening of Wnt signaling factors in advanced retinopathy of prematurity ⬇️

scientific article published on December 5, 2010

Gonadotropin regulation and role of ovarian osteopontin in the periovulatory period

scientific article published on 28 October 2014

Hyperthermotherapy enhances antitumor effect of 5-aminolevulinic acid-mediated sonodynamic therapy with activation of caspase-dependent apoptotic pathway in human glioma

scientific article published on 4 February 2016

Immunofluorescence Labeling of a Mutant of Tissue Non-Specific Alkaline Phosphatase Lacking the Glysosylphosphatidylinositol Anchor

scientific article published on January 2016

Immunoproteomic identification of anti-C9 autoimmune antibody in patients with seronegative obstetric antiphospholipid syndrome.

scientific article published on 12 June 2018

Importance of deletion of T at nucleotide 1559 in the tissue-nonspecific alkaline phosphatase gene in Japanese patients with hypophosphatasia

scientific article published on 01 January 2002

Inhibition of tissue-nonspecific alkaline phosphatase protects against medial arterial calcification and improves survival probability in the CKD-MBD mouse model

scientific article published on 23 November 2019

Molecular effects of the tissue-nonspecific alkaline phosphatase gene polymorphism (787T > C) associated with bone mineral density

scientific article

Novel aggregate formation of a frame-shift mutant protein of tissue-nonspecific alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension. Retarded secretion and proteasomal degradation

scientific article published in April 2005

Nutrition education in Japanese medical schools: a follow-up survey

scientific article

Nutrition education in medical schools in Japan: results from a questionnaire survey

scientific article published on 01 January 2006

Pathophysiology of hypophosphatasia and the potential role of asfotase alfa

scientific article

Perinatal hypophosphatasia caused by uniparental isodisomy

scientific article published on 12 December 2013

Prenatal genetic diagnosis of severe perinatal (lethal) hypophosphatasia

scientific article published on 01 February 2007

Prevalence of c.1559delT in ALPL, a common mutation resulting in the perinatal (lethal) form of hypophosphatasia in Japanese and effects of the mutation on heterozygous carriers

scientific article published on 23 December 2010

Prolonged survival and phenotypic correction of Akp2−/− hypophosphatasia mice by lentiviral gene therapy ⬇️

scientific article published on January 1, 2011

Rapid and transient upregulation of CCL11 (eotaxin-1) in mouse ovary during terminal stages of follicular development.

scientific article published on 6 January 2012

Regulation of the human tissue-nonspecific alkaline phosphatase gene expression by all-trans-retinoic acid in SaOS-2 osteosarcoma cell line

scientific article

Rescue of severe infantile hypophosphatasia mice by AAV-mediated sustained expression of soluble alkaline phosphatase

scientific article published on 8 June 2011

Retinoic acid regulates commitment of undifferentiated mesenchymal stem cells into osteoblasts and adipocytes

scientific article

The mechanism of mineralization and the role of alkaline phosphatase in health and disease

scientific article published on February 2010

The mutant (F310L and V365I) tissue-nonspecific alkaline phosphatase gene from hypophosphatasia.

scientific article

The role of bone marrow-derived cells in bone fracture repair in a green fluorescent protein chimeric mouse model

scientific article published in May 2005

The role of tissue-nonspecific alkaline phosphatase in the phosphate-induced activation of alkaline phosphatase and mineralization in SaOS-2 human osteoblast-like cells

scientific article

Up-regulation of alkaline phosphatase expression in human primary osteoblasts by cocultivation with primary endothelial cells is mediated by p38 mitogen-activated protein kinase-dependent mRNA stabilization.

scientific article published in November 2009

lncRNA HOTAIR Inhibits Mineralization in Osteoblastic Osteosarcoma Cells by Epigenetically Repressing ALPL

scientific article published on 30 May 2018

Paulina is supported by:

About Paulina

Help