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List of works by Nobuhiro Yamada

5. Cardiovascular Diseases

scientific article published on 01 April 2009

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes

scientific article published on 9 March 2017

A kindred of familial acromegaly without evidence for linkage to MEN-1 locus

scientific article

A missense mutation in kynurenine aminotransferase-1 in spontaneously hypertensive rats.

scientific article published on 26 July 2002

A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia

scientific article

A transcription factor of lipid synthesis, sterol regulatory element-binding protein (SREBP)-1a causes G(1) cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors.

scientific article published on 27 July 2007

Abdominal Irradiation Ameliorates Obesity in ob/ob Mice

scientific article

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

scientific article published on 02 June 2014

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model

scientific article

Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice

scientific article published on 28 January 2004

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice

scientific article

Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status

scientific journal article

Alcohol consumption and risk of atrial fibrillation: a meta-analysis

scientific article

Alcohol use and diabetes mellitus

scientific article published in September 2004

Antioxidants and an inhibitor of advanced glycation ameliorate death of retinal microvascular cells in diabetic retinopathy

scientific article published in January 2006

Association between physical activity and risk of all-cause mortality and cardiovascular disease in patients with diabetes: a meta-analysis.

scientific article published on February 2013

Association of cholesteryl ester transfer protein activity and TaqIB polymorphism with lipoprotein variations in Japanese subjects

scientific article published in December 2003

Background to discuss guidelines for control of plasma HDL-cholesterol in Japan

scientific article published on 12 January 2012

Body mass index and mortality among Japanese patients with type 2 diabetes: pooled analysis of the Japan diabetes complications study and the Japanese elderly diabetes intervention trial

scientific article

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.

scientific article published on 16 December 2016

Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis

scientific article

Cardiovascular event rates in patients with cerebrovascular disease and atherothrombosis at other vascular locations: results from 1-year outcomes in the Japanese REACH Registry.

scientific article published on 7 October 2009

Cardiovascular events in Japanese asymptomatic patients with type 2 diabetes: a 1-year interim report of a J-ACCESS 2 investigation using myocardial perfusion imaging

scientific article published in December 2009

Carotid artery plaque and LDL-to-HDL cholesterol ratio predict atherosclerotic status in coronary arteries in asymptomatic patients with type 2 diabetes mellitus.

scientific article

Cerebral hemorrhagic infarction after radiation for pituitary adenoma.

scientific article published in October 2002

Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity

scientific article

Cigarette Smoking Is Associated With Low Glomerular Filtration Rate in Male Patients With Type 2 Diabetes: Response to De Cosmo et al

scientific article published on 01 March 2007

Clinical effects of rosuvastatin, a new HMG-CoA reductase inhibitor, in Japanese patients with primary hypercholesterolemia: an early phase II study

scientific article published in January 2002

Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia. Dose-finding study using the double-blind, three-group parallel comparison

scientific article published in January 2002

Clinical features of familial hypercholesterolemia in Japan in a database from 1996-1998 by the research committee of the ministry of health, labour and welfare of Japan

scientific article published on 01 January 2004

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.

scientific article

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

scientific article published in June 2005

Cohort profile: The Japan diabetes complications study: a long-term follow-up of a randomised lifestyle intervention study of type 2 diabetes.

scientific article

Comparison of various lipid variables as predictors of coronary heart disease in Japanese men and women with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study

scientific article published on 14 February 2012

Components of metabolic syndrome and their combinations as predictors of cardiovascular disease in Japanese patients with type 2 diabetes. Implications for improved definition. Analysis from Japan Diabetes Complications Study (JDCS).

scientific article

Cross-sectional association between BMI, glycemic control and energy intake in Japanese patients with type 2 diabetes

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of L

scientific article published in May 2003

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling

scientific article published on May 2003

Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice

scientific article

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

scientific article published on 30 September 2007

Cutting-edge of medicine; clinical epidemiology regarding clinical and pathophysiological features of Japanese patients with type 2 diabetes mellitus

scientific article published in October 2013

Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.

scientific article published on 29 April 2008

Development of a screening score for undiagnosed diabetes and its application in estimating absolute risk of future type 2 diabetes in Japan: Toranomon Hospital Health Management Center Study 10 (TOPICS 10).

scientific article published on 7 February 2013

Diabetes and risk of hearing impairment in adults: a meta-analysis.

scientific article

Diabetic retinopathy and microalbuminuria can predict macroalbuminuria and renal function decline in Japanese type 2 diabetic patients: Japan Diabetes Complications Study

scientific article published on 25 April 2013

Diagnosis and Management of Type I and Type V Hyperlipoproteinemia

scientific article published on 01 December 2011

Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells

scientific article published on 26 March 2012

Dietary intake in Japanese patients with type 2 diabetes: Analysis from Japan Diabetes Complications Study

scientific article

Dietary sodium intake and incidence of diabetes complications in Japanese patients with type 2 diabetes: analysis of the Japan Diabetes Complications Study (JDCS).

scientific article published on 22 July 2014

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice

scientific article

Distinct effects of pravastatin, atorvastatin, and simvastatin on insulin secretion from a beta-cell line, MIN6 cells

scientific article published on December 2006

Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha

scientific article published in January 2002

Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene

scientific journal article

Effect of rosuvastatin 5-20mg on triglycerides and other lipid parameters in Japanese patients with hypertriglyceridemia.

scientific article

Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats

scientific article

Effects of atorvastatin on glucose metabolism and insulin resistance in KK/Ay mice

scientific article published in January 2005

Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study

scientific article

Effects of pioglitazone hydrochloride on Japanese patients with type 2 diabetes mellitus

scientific article published in April 2007

Eicosapentaenoic acid suppresses basal and insulin-stimulated endothelin-1 production in human endothelial cells

scientific article published on August 2003

Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.

scientific article

Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.

scientific article

Elovl6 promotes nonalcoholic steatohepatitis

scientific article published on 01 December 2012

Energy intake and obesity in Japanese patients with type 2 diabetes

scientific article published in January 2004

Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition

scientific article published on 24 November 2020

Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860).

scientific article published in November 2004

Even Low-Intensity and Low-Volume Exercise Training May Improve Insulin Resistance in the Elderly

scientific article published on 17 July 2007

Fasting and post-challenge glucose as quantitative cardiovascular risk factors: a meta-analysis.

scientific article published on 11 January 2012

Fidarestat (SNK-860), a potent aldose reductase inhibitor, normalizes the elevated sorbitol accumulation in erythrocytes of diabetic patients

scientific article published in March 2002

Fruit intake and incident diabetic retinopathy with type 2 diabetes

scientific article published in March 2013

Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

scientific article published on January 2013

Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice

scientific journal article

HMG-CoA reductase inhibitor decreases small dense low-density lipoprotein and remnant-like particle cholesterol in patients with type-2 diabetes

scientific article published in October 2002

HbA1c 5·7-6·4% and impaired fasting plasma glucose for diagnosis of prediabetes and risk of progression to diabetes in Japan (TOPICS 3): a longitudinal cohort study

scientific article published on 24 June 2011

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

scientific article published in December 2003

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.

scientific article published on 18 September 2014

High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding

scientific article

Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.

scientific article published on 18 July 2009

Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.

scientific article

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

scientific article published on 13 June 2016

Identification of ISG12b as a putative interferon-inducible adipocytokine which is highly expressed in white adipose tissue

scientific article published on 14 August 2007

Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis

scientific journal article

Identification of human ELOVL5 enhancer regions controlled by SREBP

scientific article published on 28 August 2015

Impact of introducing HbA1c into the diagnostic criteria on prevalence and cardiovascular risk profiles of individuals with newly diagnosed diabetes in Japan: the Toranomon Hospital Health Management Center Study 2 (TOPICS 2).

scientific article published on 21 November 2011

Importance of lipid levels in elderly diabetic individuals: baseline characteristics and 1-year survey of cardiovascular events

scientific article published in February 2008

In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression

scientific article

Influence of fat and carbohydrate proportions on the metabolic profile in patients with type 2 diabetes: a meta-analysis.

scientific article published on May 2009

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice

scientific article published on 12 September 2011

Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway

scientific article published on March 2002

Insulin sensitizers and atherosclerosis

scientific article

Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice

scientific article published in March 2004

Intakes of dietary fiber, vegetables, and fruits and incidence of cardiovascular disease in Japanese patients with type 2 diabetes

scientific article published on 29 October 2013

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.

scientific article published on 17 September 2016

Involvement of glomerular SREBP-1c in diabetic nephropathy

scientific article published on 16 October 2007

Is the diagnosis of metabolic syndrome useful for predicting cardiovascular disease in asian diabetic patients? Analysis from the Japan Diabetes Complications Study

scientific article published in June 2005

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.

scientific article published on 17 August 2016

Lipid synthetic transcription factor SREBP-1a activates p21WAF1/CIP1, a universal cyclin-dependent kinase inhibitor

scientific article published on October 2005

Lipolysis in the absence of hormone-sensitive lipase: evidence for a common mechanism regulating distinct lipases

scientific article published in December 2002

Long-term multiple risk factor interventions in Japanese elderly diabetic patients: the Japanese Elderly Diabetes Intervention Trial--study design, baseline characteristics and effects of intervention

scientific article published in April 2012

Longitudinal trajectories of HbA1c and fasting plasma glucose levels during the development of type 2 diabetes: the Toranomon Hospital Health Management Center Study 7 (TOPICS 7)

scientific article published on 28 March 2012

Low HDL cholesterol is associated with the risk of stroke in elderly diabetic individuals: changes in the risk for atherosclerotic diseases at various ages

scientific article published on 09 June 2009

Low lung function and risk of type 2 diabetes in Japanese men: the Toranomon Hospital Health Management Center Study 9 (TOPICS 9)

scientific article

Macrophage Elovl6 Deficiency Ameliorates Foam Cell Formation and Reduces Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

scientific article published on 04 August 2011

Management of Type IIb Dyslipidemia

scientific article published on 03 December 2011

Maximum BMI and microvascular complications in a cohort of Japanese patients with type 2 diabetes: the Japan Diabetes Complications Study

scientific article published on 2 March 2016

Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes

scientific article published on 18 July 2008

Mouse Elovl-6 promoter is an SREBP target.

scientific article published on 28 January 2008

Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter

scientific journal article

Mutations in Japanese subjects with primary hyperlipidemia--results from the Research Committee of the Ministry of Health and Welfare of Japan since 1996--.

scientific article published in January 2004

Non-high-density lipoprotein cholesterol: An important predictor of stroke and diabetes-related mortality in Japanese elderly diabetic patients

scientific article published on 01 April 2012

Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia

scientific article published in 2000

Nuclear SREBP-1a causes loss of pancreatic beta-cells and impaired insulin secretion

scientific article

Obesity and type 2 diabetes in Japanese patients

scientific article published in The Lancet

Outcome of One-year of Specialist Care of Patients with Type 2 Diabetes: A Multi-Center Prospective Survey (JDDM 2)

scientific article published on 01 June 2006

PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

scientific journal article

PPAR gamma ligands, troglitazone and pioglitazone, up-regulate expression of HMG-CoA synthase and HMG-CoA reductase gene in THP-1 macrophages

scientific article

Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets

scientific article published on 5 May 2008

Physiological changes in circulating mannose levels in normal, glucose-intolerant, and diabetic subjects

scientific article published in August 2003

Plasma chloride concentration as a new diagnostic indicator of insulin insufficiency

scientific article published in February 2005

Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000.

scientific article

Polymorphisms of apolipoprotein e and methylenetetrahydrofolate reductase in the Japanese population

scientific article published on 14 August 2007

Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression

scientific article published on December 2003

Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.

scientific article

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

scientific article

Predicting macro- and microvascular complications in type 2 diabetes: the Japan Diabetes Complications Study/the Japanese Elderly Diabetes Intervention Trial risk engine

scientific article published on 12 February 2013

Prevalence of metabolic syndrome in the general Japanese population in 2000

scientific article published on 01 August 2006

Prevalence, awareness and treatment of cardiovascular risk factors in patients at high risk of atherothrombosis in Japan

scientific article published in July 2007

Preventing angiographic progression of coronary atherosclerosis with pravastatin

scientific article published in January 2003

Prevention and therapeutic strategy of metabolic syndrome--implications from the interim results of Japan Diabetes Complications Study(JDCS)

scientific article

Prognostic value of gated myocardial perfusion imaging for asymptomatic patients with type 2 diabetes: the J-ACCESS 2 investigation ⬇️

scientific article

Proposed guidelines for hypertriglyceridemia in Japan with non-HDL cholesterol as the second target

scientific article published in June 2008

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver

scientific article published on 12 February 2007

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.

scientific article

R46Q mutation in the succinate dehydrogenase B gene (SDHB) in a Japanese family with both abdominal and thoracic paraganglioma following metastasis

scientific article

Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)-a randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events

scientific article

Receptor-type protein tyrosine phosphatase epsilon (PTPepsilonM) is a negative regulator of insulin signaling in primary hepatocytes and liver

scientific journal article

Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis

scientific article published on 31 October 2006

Report of the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese adults

scientific article published on January 2002

Requirement for hypertension and hyperlipidemia medication in U.S. and Japanese patients with diabetes

scientific article published on 01 November 2004

Resistin is regulated by C/EBPs, PPARs, and signal-transducing molecules

scientific article published on November 2002

Risk imparted by various parameters of smoking in Japanese men with type 2 diabetes on their development of microalbuminuria: analysis from the Tsukuba Kawai Diabetes Registry

scientific article published on 2 March 2007

Risk of cardiovascular diseases is increased even with mild diabetic retinopathy: the Japan Diabetes Complications Study

scientific article published on 20 November 2012

Risk stratification based on metabolic syndrome as well as non- metabolic risk factors in the assessment of carotid atherosclerosis.

scientific article published on 18 March 2011

Role of alcohol drinking pattern in type 2 diabetes in Japanese men: the Toranomon Hospital Health Management Center Study 11 (TOPICS 11).

scientific article

SPARC is a major secretory gene expressed and involved in the development of proliferative diabetic retinopathy

scientific article

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

scientific article

SREBP-1-independent regulation of lipogenic gene expression in adipocytes.

scientific article published on 24 April 2007

SREBPs suppress IRS-2-mediated insulin signalling in the liver

scientific article published on 14 March 2004

Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide

scientific article

Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.

scientific article published on 13 January 2017

Self-reported fast eating is a potent predictor of development of impaired glucose tolerance in Japanese men and women: Tsukuba Medical Center Study

scientific article

Serum level of triglycerides is a potent risk factor comparable to LDL cholesterol for coronary heart disease in Japanese patients with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study (JDCS).

scientific article published on 24 August 2011

Serum lipid survey and its recent trend in the general Japanese population in 2000.

scientific article

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

scientific article published on 14 September 2015

Skipping breakfast and prevalence of overweight and obesity in Asian and Pacific regions: a meta-analysis.

scientific article published on 27 August 2011

Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages

scientific article published on April 2004

Sterol Regulatory Element–Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

scientific article published on 05 May 2011

Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47.

scientific article published on 29 July 2005

Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).

scientific article published on 7 June 2011

Surveillance study for creating the national clinical database relating to ECG-gated myocardial perfusion SPECT of asymptomatic ischemic heart disease in patients with type-2 diabetes mellitus: J-ACCESS 2 study design

scientific article

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis

scientific article published on 24 July 2013

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.

scientific article published on 2 December 2012

TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice

scientific article

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

scientific article published on 4 December 2005

The Long-Term Effects of Self-Management Education for Patients With Type 2 Diabetes on Glycemic Control: Response to Norris et al

scientific article published on 01 November 2002

The effect of exercise training on adiponectin receptor expression in KKAy obese/diabetic mice

scientific article published on 01 June 2006

The effects of partial use of formula diet on weight reduction and metabolic variables in obese type 2 diabetic patients--multicenter trial

scientific article published in January 2013

The lack of long-range negative correlations in glucose dynamics is associated with worse glucose control in patients with diabetes mellitus

scientific article published on 02 February 2012

The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.

scientific article published on 16 December 2009

The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions: additional analysis from the Japan Diabetes Complications Study

scientific article published in January 2006

The relationship between non-HDL cholesterol and other lipid parameters in Japanese subjects

scientific article published in January 2005

The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice

scientific article published on 19 May 2009

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

scientific journal article

Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance

scientific article published on 01 June 2018

Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes

scientific article published on 16 December 2004

Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells

scientific article

Type 2 Diabetes Prevalence in Asian Subjects: Response to McNeely and Boyko

article

Ursodeoxycholic acid inhibits endothelin-1 production in human vascular endothelial cells

scientific article

Vascular endothelial growth factor gene expression in a retinal pigmented cell is up-regulated by glucose deprivation through 3' UTR.

scientific article

WGEF is a novel RhoGEF expressed in intestine, liver, heart, and kidney.

scientific article

Waist circumference as a cardiovascular and metabolic risk in Japanese patients with type 2 diabetes.

scientific article published on 20 November 2008

[Japan Diabetes Complications Study (JDCS)]

scientific article published on 01 May 2012

[Japan Diabetes Complications Study (JDCS)]

scientific article published on 01 May 2010

[Large-scale randomized intervention trial on diabetes in Japan]

scientific article published on 01 October 2002

[Long-term intervention studies of diabetic macroangiopathy in Japan and western countries]

scientific article published on 01 November 2006

[Metabolic syndrome in Japanese patient with diabetes analysis from JDCS]

scientific article published on 01 December 2006

[PPARs in atherosclerosis]

scientific article published on 01 April 2005

[Prevalence and incidence of diabetic microangiopathy in Japan]

scientific article published on 01 June 2005

[Recent studies on hyperlipidemia]

scientific article published on 01 April 2002

[Recent trends in diabetic complications in Japan]

scientific article published on 01 November 2004

[The present situation and future problems on diabetic complications in Japan]

scientific article published on 01 July 2012

[Vascular dysfunction in metabolic syndrome: 2) Risk for coronary artery disease]

scientific article published on 01 April 2004

p53 Activation in Adipocytes of Obese Mice ⬇️

scientific article published on May 6, 2003

p53 involvement in the pathogenesis of fatty liver disease.

scientific article published on 25 February 2004

p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus

scientific article (publication date: 26 December 2003)

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