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List of works by Robert Alpern

A consensus sequence in the endothelin-B receptor second intracellular loop is required for NHE3 activation by endothelin-1.

scientific article published on 14 December 2004

Acid Stimulation of the Citrate Transporter NaDC-1 Requires Pyk2 and ERK1/2 Signaling Pathways

scientific article published on 20 April 2018

Acid activation of immediate early genes in renal epithelial cells

scientific article

Acid incubation causes exocytic insertion of NHE3 in OKP cells

scientific article published on 01 August 2000

Acid incubation increases NHE-3 mRNA abundance in OKP cells ⬇️

scientific article published on July 1, 1995

Acid regulation of NaDC-1 requires a functional endothelin B receptor.

scientific article published on 11 August 2010

Active and passive components of chloride transport in the rat proximal convoluted tubule

scientific article

Adenosine triphosphate citrate lyase mediates hypocitraturia in rats

scientific article

Amiloride inhibition of proximal tubular acidification

scientific article published in June 1985

An autocrine role for endothelin-1 in the regulation of proximal tubule NHE3.

scientific article

Angiotensin II stimulation of Na-H antiporter activity is cAMP independent in OKP cells

scientific article published on June 1994

Basolateral membrane H-OH-HCO3 transport in the proximal tubule

scientific article

Basolateral membrane H/HCO3 transport in renal tubules

scientific article published on 01 June 1991

Basolateral membrane H/OH/HCO3 transport mechanisms along the nephron: role in control of pHi and transepithelial bicarbonate transport

scientific article published on March 1990

Basolateral membrane Na/base cotransport is dependent on CO2/HCO3 in the proximal convoluted tubule

scientific article

Bicarbonate reabsorption and NHE-3 expression: abundance and activity are increased in Henle's loop of remnant rats

scientific article published in December 2002

Carbonic anhydrase inhibitors.

scientific article published on January 1987

Cellular model of proximal tubule NaCl and NaHCO3 absorption

scientific article published on October 1990

Chronic K depletion stimulates rat renal brush-border membrane Na-citrate cotransporter ⬇️

scientific article published on November 1, 1991

Chronic adaptations in proximal tubular H/HCO3 transporters

scientific article published on July 1, 1991

Chronic hyperosmolality increases NHE3 activity in OKP cells ⬇️

scientific article published on January 1, 1998

Chronic metabolic acidosis causes an adaptation in the apical membrane Na/H antiporter and basolateral membrane Na(HCO3)3 symporter in the rat proximal convoluted tubule

scientific article published on October 1988

Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 mRNA.

scientific article published on January 1997

Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney

scientific article published on 01 October 1996

Chronic metabolic acidosis increases NaDC-1 mRNA and protein abundance in rat kidney

scientific article published on 01 July 2000

Chronic regulation of the Na/H antiporter.

scientific article published on August 1993

Chronic regulation of the proximal tubular Na/H antiporter: from HCO3 to SRC

scientific article published on 01 November 1995

Citraturic response to oral citric acid load

scientific article published on 01 April 1992

Contrasting effects of various potassium salts on renal citrate excretion

scientific article published on 01 February 1991

Contributions of cellular leak pathways to net NaHCO3 and NaCl absorption

scientific article

Converting enzyme inhibition causes hypocitraturia independent of acidosis or hypokalemia

scientific article published on 01 November 1998

Cyclic adenosine monophosphate acutely inhibits and chronically stimulates Na/H antiporter in OKP cells ⬇️

scientific article published on October 1, 1993

Defining hypercalciuria in nephrolithiasis ⬇️

scientific article published on July 20, 2011

Dietary NaCl modulates Na(+)-H+ antiporter activity in renal cortical apical membrane vesicles ⬇️

scientific article published on 01 January 1991

Dietary acid, endothelins, and sleep.

scientific article published on January 2004

Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts ⬇️

scientific article published on November 1, 1991

Does hyperphosphaturia underlie hypercalciuria?

scientific article published on 01 February 1997

Dominant negative c-Src inhibits angiotensin II induced activation of NHE3 in OKP cells ⬇️

scientific article published on August 1, 1998

ET(B) receptor activation causes exocytic insertion of NHE3 in OKP cells

scientific article

ETB receptor activation leads to activation and phosphorylation of NHE3.

scientific article published on April 1999

Effect of glucocorticoids on renal cortical NHE-3 and NHE-1 mRNA

scientific article published on 01 September 1994

Effect of luminal bicarbonate concentration on proximal acidification in the rat

scientific article published on 01 July 1982

Effects of endothelin on in vitro renin secretion

scientific article published on April 1991

Effects of thyroid hormone on the neonatal renal cortical Na+/H+ antiporter ⬇️

scientific article published on May 1, 1998

Endothelin(B) receptor activates NHE-3 by a Ca2+-dependent pathway in OKP cells

scientific article published on March 1996

Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis

scientific article

Evidence for electroneutral sodium chloride transport in rat proximal convoluted tubule

scientific article published on 01 April 1986

Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb

scientific article published on 01 October 1995

Flow dependence of proximal tubular bicarbonate absorption

scientific article published on 01 October 1983

Glucagon acutely inhibits but chronically activates Na(+)/H(+) antiporter 3 activity in OKP cells

scientific article published on 01 January 2002

Glucocorticoids enhance acid activation of the Na+/H+ exchanger 3 (NHE3)

scientific article

Glucocorticoids regulate NHE-3 transcription in OKP cells

scientific article

Increased Na/H antiporter and Na/3HCO3 symporter activities in chronic hyperfiltration. A model of cell hypertrophy ⬇️

scientific article published on February 1, 1991

Increased Vmax for Na+/H+ antiporter activity in proximal tubule brush border vesicles from rabbits with metabolic acidosis

scientific article published on 01 August 1984

Intracellular acidosis activates c-Src

scientific article published on March 1997

Long-term activation of protein kinase c causes chronic Na/H antiporter stimulation in cultured proximal tubule cells ⬇️

scientific article published on February 1, 1992

Media acidification inhibits TGF beta-mediated growth suppression in cultured rabbit proximal tubule cells

scientific article published on 01 November 1997

Na+/H+ antiporter (NHE-1 isoform) in cultured vascular smooth muscle from the spontaneously hypertensive rat

scientific article published on 01 January 1995

OKP cells express the Na-dicarboxylate cotransporter NaDC-1.

scientific article published on 18 February 2004

Overexpression of csk inhibits acid-induced activation of NHE-3.

scientific article

Pathways for apical and basolateral membrane NH3 and NH4+ movement in rat proximal tubule

scientific article published on 01 October 1990

Preincubation in acid medium increases Na/H antiporter activity in cultured renal proximal tubule cells

scientific article

Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3.

scientific article

Regulation of cell pH by ambient bicarbonate, carbon dioxide tension, and pH in the rabbit proximal convoluted tubule

scientific article published on February 1988

Regulation of proximal reabsorption by effective arterial blood volume

scientific article published on March 1991

Renal Na/H exchanger NHE-3 and Na-PO4 cotransporter NaPi-2 protein expression in glucocorticoid excess and deficient states ⬇️

scientific article published on September 1, 1998

Renal citrate metabolism and urinary citrate excretion in the infant rat.

scientific article

Renal cortical mitochondrial aconitase is regulated in hypo- and hypercitraturia ⬇️

scientific article published on July 1, 1998

Renin expression in renal proximal tubule ⬇️

scientific article published on March 1, 1993

RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3.

scientific article published on 8 August 2007

Role of c-SRC and ERK in acid-induced activation of NHE3

scientific journal article

Role of protein kinase C and transcription factor AP-1 in the acid-induced increase in Na/H antiporter activity ⬇️

scientific article published on June 15, 1992

Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption

scientific article published on October 1987

The clinical spectrum of chronic metabolic acidosis: homeostatic mechanisms produce significant morbidity

scientific article published on 01 February 1997

The renal proximal tubule renin-angiotensin system

scientific article

The role of endothelin in proximal tubule proton secretion and the adaptation to a chronic metabolic acidosis

scientific article

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