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List of works by Birgit Knoechel

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

scientific article

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.

scientific article

Balance of Th1 and Th17 effector and peripheral regulatory T cells

scientific article published on 17 April 2009

Balancing autoaggressive and protective T cell responses

scientific article published on 23 March 2007

Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case

scientific article published on October 2015

Comprehensive characterization of circulating and bone marrow-derived multiple myeloma cells at minimal residual disease

scientific article published on 01 January 2018

Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance

scientific article published in March 2008

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

scientific article

Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma

scientific article

Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma

scientific article published on 21 October 2021

EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma

scientific article published on 30 October 2014

Functional and molecular comparison of anergic and regulatory T lymphocytes

scientific article

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

scientific article

Genetic interrogation of circulating multiple myeloma cells at single-cell resolution

scientific article

Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing

scientific article published on 27 March 2018

Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes

scientific article published on 21 July 2013

IL-2 induces a competitive survival advantage in T lymphocytes

scientific article published in May 2004

Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

scientific article published in 2022

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia

scientific article

Metabolic Mechanisms of Drug Resistance in Leukemia

scientific article

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia

article

Peptidomimetic blockade of MYB in acute myeloid leukemia

scientific article published on 9 January 2018

Regulatory T cells in the periphery

scientific article published on August 2006

Role of B7 in T cell tolerance

scientific article published on 01 October 2004

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

scientific article

Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen

scientific article

Single cell RNA-seq reveals developmental plasticity with coexisting oncogenic and immune evasion programs in ETP-ALL

scientific article published on 23 November 2020

Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in <i>BRAF</i>-Mutated Multiple Myeloma

scientific article published on 13 September 2021

T cell tolerance and autoimmunity

T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens

scientific article

The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens

scientific article published on 25 May 2003

The link between lymphocyte deficiency and autoimmunity: roles of endogenous T and B lymphocytes in tolerance

scientific article

Tracking myeloma tumor DNA in peripheral blood

scientific article published on 14 January 2020

Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy

scientific article published in January 2014

Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma

scientific article published on 12 September 2018

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