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List of works by Richard B. Horenstein

A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection

scientific article published on December 2008

Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome.

scientific article

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy

scientific article

CYP2C19 metabolizer status and clopidogrel efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) study

scientific article

Development of a physiology-directed population pharmacokinetic and pharmacodynamic model for characterizing the impact of genetic and demographic factors on clopidogrel response in healthy adults

scientific article published on 30 October 2015

Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers

scientific article

Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish

scientific article published on November 2010

Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes

scientific article published on 07 February 2013

Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response

scientific article published on 15 February 2017

Mapping Genes in Isolated Populations: Lessons from the Old Order Amish

article

Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes

scientific article

Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study

scientific article published on 26 October 2015

Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes).

scientific article published on 28 March 2017

The ABCG8 G574R variant, serum plant sterol levels, and cardiovascular disease risk in the Old Order Amish

scientific article published on 13 December 2012

The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin

scientific article published on 15 September 2015

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

scientific article published on January 2013

The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study

scientific article published on 5 March 2008

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