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List of works by Szymon Klossowski

Abstract 5347: SK053, a small molecule inhibitor of enzymes involved in allosteric disulfide bonds formation, shows potent anti-leukemic effects and induces differentiation of human AML cells

Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML with activating FLT3 mutations

scientific article published on 05 September 2020

Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction

scientific article published on 23 May 2018

Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C.

scientific article published on 04 September 2016

Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma.

scientific article published on 30 November 2015

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

scientific article published on 14 May 2021

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia

scientific article published on 01 February 2020

Menin regulates the serine biosynthetic pathway in Ewing sarcoma.

scientific article published on 19 April 2018

Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of PEG10 and Blocks Hepatocellular Carcinoma

scientific article published on 15 November 2017

Synthesis of novel, peptidic kinase inhibitors with cytostatic/cytotoxic activity.

scientific article

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