Search filters

List of works by Sabrina Cipriani

Activation of FXR Improves Myocardial Fatty Acid Metabolism in a Rodent Model of Liver Steatosis

scholarly article published in May 2011

Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non‐steroidal anti‐inflammatory drugs and aspirin in mice ⬇️

scientific article published on January 1, 2013

Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice ⬇️

scientific article published on December 1, 2011

Anti-HIV Protease Inhibitors Interact With NSAIDs and Exacerbate Small Intestine Enteropathy Induced by NSAIDs

scholarly article published in May 2011

Anti-inflammatory activity of a new class of nitric oxide synthase inhibitors that release nitric oxide

scientific article

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis

scientific article published on 16 February 2017

Bile acid activated receptors are targets for regulation of integrity of gastrointestinal mucosa

scientific article

Bile acid-activated receptors in the treatment of dyslipidemia and related disorders

scientific article published on 02 December 2009

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders

scientific article

CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination.

scientific article

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis.

scientific article published on 29 January 2013

Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids

article

Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis

scientific article published on 24 January 2017

Development of non-antibiotic macrolide that corrects inflammation-driven immune dysfunction in models of inflammatory bowel diseases and arthritis ⬇️

scientific article published on April 28, 2011

Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis

scientific article (publication date: 2012)

Dissociation of intestinal and hepatic activities of FXR and LXRα supports metabolic effects of terminal ileum interposition in rodents.

scientific article published on 08 July 2013

Efficacy of the CCR5 antagonist maraviroc in reducing early, ritonavir-induced atherogenesis and advanced plaque progression in mice.

scientific article published on 30 April 2013

Essential Role of DNAX Adaptor Protein 12 (DAP12) and Spleen Tyrosine Kinase (Syk) in Inflammation-Driven Immune Dysfunction in Rodent Model of Colitis.

scholarly article published in May 2011

Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.

scientific article

FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats

scientific article

FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents.

scientific article published in September 2013

Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter.

scientific article published on 4 February 2011

Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases

scientific article published in December 2017

Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition.

scientific article published on 23 March 2012

Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice.

scientific article

Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis

scientific article published on 05 August 2016

Hydrogen sulphide induces micro opioid receptor-dependent analgesia in a rodent model of visceral pain

scientific article published on 11 June 2010

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists

scientific article

Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling

scientific article published on 15 July 2015

In vivo administration of ritonavir worsens intestinal damage caused by cyclooxygease inhibitors

scientific article published on 4 December 2013

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists.

scientific article published on 7 January 2016

Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity

scientific article published on 19 November 2015

Mechanistic role of p38 MAPK in gastric cancer dissemination in a rodent model peritoneal metastasis.

scientific article

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity.

scientific article published on 28 July 2017

Modification on ursodeoxycholic acid (UDCA) scaffold. discovery of bile acid derivatives as selective agonists of cell-surface G-protein coupled bile acid receptor 1 (GP-BAR1)

scientific article published on 07 September 2014

Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP

scientific article

Molecular Determinants of Gastrointestinal and Liver Cancers: Role of Bile Acid Activated Nuclear Receptors ⬇️

scientific article published on January 1, 2012

Nanotraps with biomimetic surface as decoys for chemokines

scientific article published on 26 July 2017

Pregnane-X-receptor mediates the anti-inflammatory activities of rifaximin on detoxification pathways in intestinal epithelial cells ⬇️

scientific article published on September 9, 2010

Probiotics VSL#3 protect against development of visceral pain in murine model of irritable bowel syndrome

scientific article

Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation

scientific article

Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1.

scientific article published on 5 November 2015

Ritonavir-induced lipoatrophy and dyslipidaemia is reversed by the anti-inflammatory drug leflunomide in a PPAR-γ-dependent manner

scientific article published on 25 January 2012

SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts ⬇️

scientific article published on January 29, 2011

Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis.

scientific article published on 24 December 2013

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases

scientific article published on 30 March 2017

Targetting farnesoid-X-receptor: from medicinal chemistry to disease treatment

scientific article published on January 2010

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis ⬇️

scientific article published on October 27, 2011

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.

scientific article

The Bile Acid Sensor FXR Protects against Dyslipidemia and Aortic Plaques Development Induced by the HIV Protease Inhibitor Ritonavir in Mice ⬇️

scientific article published on October 8, 2010

The Bile Acids Receptor TGR5 is an Essential Modulator of Intestinal Membrane Permeability and Exerts Anti-Inflammatory Activities in Rodent Model of Colitis

scholarly article published in May 2011

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.

scientific article published on 15 October 2015

The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2.

scientific article

The HIV matrix protein p17 subverts nuclear receptors expression and induces a STAT1-dependent proinflammatory phenotype in monocytes ⬇️

scientific article published on April 30, 2012

The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines.

scientific article published on 07 July 2016

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

scientific journal article

The bile acid sensor farnesoid X receptor is a modulator of liver immunity in a rodent model of acute hepatitis

scientific article published on 30 October 2009

The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate

scientific article

VSL#3 Resets Insulin Signaling and Protects against NASH and Atherosclerosis in a Model of Genetic Dyslipidemia and Intestinal Inflammation ⬇️

scientific article published on September 21, 2012

Paulina is supported by:

About Paulina

Help