List of works by Brian H Kushner

131I-3F8: clinical validation of imaging studies and therapeutic applications

scientific article published on 01 January 1991

3F8 monoclonal antibody treatment of patients with stage 4 neuroblastoma: a phase II study

scientific article published on 01 June 1998

3F8 monoclonal antibody treatment of patients with stage IV neuroblastoma: a phase II study

scientific article published on 01 January 1994

5-day/5-drug myeloablative outpatient regimen for resistant neuroblastoma

scientific article

A focal lesion in the falx cerebri: Harbinger of classic stage 4 neuroblastoma in an infant cured despite residual disease after minimal therapy.

scientific article

A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors

scientific article

A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma

scientific article published on 20 September 2016

Absolute requirement of CD11/CD18 adhesion molecules, FcRII and the phosphatidylinositol-linked FcRIII for monoclonal antibody-mediated neutrophil antihuman tumor cytotoxicity ⬇️

scientific article published on March 15, 1992

Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study

scientific article published on 10 May 2018

Allelic loss of chromosome 1p in neuroblastoma

scientific article published on 01 June 1996

Anti-G(D2) antibody treatment of minimal residual stage 4 neuroblastoma diagnosed at more than 1 year of age

scientific article published on 01 September 1998

Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma

scientific article

Arsenic Trioxide as a Radiation Sensitizer for 131I-Metaiodobenzylguanidine Therapy: Results of a Phase II Study

scientific article

Assessment of pulmonary outcomes, exercise capacity, and longitudinal changes in lung function in pediatric survivors of high-risk neuroblastoma

scientific article published on 12 August 2019

Autografting with bone marrow exposed to multiple courses of very high dose cyclophosphamide in vivo and to 4-hydroperoxycyclophosphamide in vitro

scientific article published on 01 January 1990

Bevacizumab-associated Bowel Microperforation in a Patient With Neuroblastoma.

scientific article

Brain-sparing radiotherapy for neuroblastoma skull metastases

scientific article published on 01 June 2008

CMET-28. IMPACT OF DISEASE SITE, SIZE AND SURGICAL RESECTION ON SURVIVAL FROM METASTATIC CNS NEUROBLASTOMA

Camptothecin analogs (irinotecan or topotecan) plus high-dose cyclophosphamide as preparative regimens for antibody-based immunotherapy in resistant neuroblastoma

scientific article

Chronic neuroblastoma

scientific article published in September 2002

Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p.

scientific article

Clinical, pathologic, and molecular spectrum of tumors associated with t(11;22)(p13;q12): desmoplastic small round-cell tumor and its variants

scientific article published on 01 September 1998

Clinically critical impact of molecular genetic studies in pediatric solid tumors

scientific article published on 01 December 1999

Clinically effective monoclonal antibody 3F8 mediates nonoxidative lysis of human neuroectodermal tumor cells by polymorphonuclear leukocytes ⬇️

scientific article published on September 15, 1991

Combination of bevacizumab, irinotecan, and temozolomide for refractory or relapsed neuroblastoma: Results of a phase II study

scientific article

Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma

scientific article

Correlation of MYCN amplification, Trk-A and CD44 expression with clinical stage in 250 patients with neuroblastoma

scientific article published on 01 October 1997

Curability of recurrent disseminated disease after surgery alone for local-regional neuroblastoma using intensive chemotherapy and anti-G(D2) immunotherapy

scientific article published in July 2003

Cyclophosphamide and the heart

scientific article published in March 1991

Cyclophosphamide versus ifosfamide in paediatric oncology

scientific article

Desmoplastic small round cell tumor 20 years after its discovery

scientific article published on January 2015

Desmoplastic small round cell tumors: prognostic indicators and results of surgical management

scientific article published on 01 July 1998

Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy

scientific article published on 01 May 1996

Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

scientific article

Detection of metastatic neuroblastoma in bone marrow: when is routine marrow histology insensitive? ⬇️

scientific article published on 01 August 1997

Detection of neuroblastoma in bone marrow by immunocytology: is a single marrow aspirate adequate?

scientific article published on 01 February 1999

Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma

scientific article published in June 2010

Disaloganglioside GD2 loss following monoclonal antibody therapy is rare in neuroblastoma.

scientific article

Disialoganglioside G(D2) loss following monoclonal antibody therapy is rare in neuroblastoma.

scientific article

Dose-escalation is needed for gross disease in high-risk neuroblastoma.

scientific article published on 22 February 2018

Dose-intensive use of cyclophosphamide in ablation of neuroblastoma

scientific article published in September 1990

Early Molecular Response of Marrow Disease to Biologic Therapy Is Highly Prognostic in Neuroblastoma ⬇️

scientific article published on October 15, 2003

Effect of low-dose radiation therapy when combined with surgical resection for Ewing sarcoma

scientific article published on 01 August 1999

Enigmatic entities: opsoclonus myoclonus ataxia syndrome linked to neuroblastoma

scientific article published on 04 November 2017

Exploiting the MIBG-avidity of neuroblastoma for staging and treatment

scientific article published on 01 December 2006

Extending positron emission tomography scan utility to high-risk neuroblastoma: fluorine-18 fluorodeoxyglucose positron emission tomography as sole imaging modality in follow-up of patients

scientific article published in July 2001

FCGR2APolymorphism Is Correlated With Clinical Outcome After Immunotherapy of Neuroblastoma With Anti-GD2 Antibody and Granulocyte Macrophage Colony-Stimulating Factor

article by Nai-Kong V. Cheung et al published 20 June 2006 in Journal of Clinical Oncology

Favorable-biology neuroblastoma presenting with leptomeningeal metastases?: a case presentation

scientific article published on 01 November 2004

Five-day courses of irinotecan as palliative therapy for patients with neuroblastoma.

scientific article

GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma

scientific article

Granulocyte-colony stimulating factor and multiple cycles of strongly myelosuppressive alkylator-based combination chemotherapy in children with neuroblastoma

scientific article

High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors

scientific article published in September 1998

High-dose carboplatin-irinotecan-temozolomide: treatment option for neuroblastoma resistant to topotecan

scientific article

High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy

scientific article published in April 2007

High-dose cyclophosphamide-irinotecan-vincristine for primary refractory neuroblastoma

scientific article published on 08 October 2010

High-dose melphalan with 6-hydroxydopamine-purged autologous bone marrow transplantation for poor-risk neuroblastoma

scientific article published on 01 July 1991

Highly effective induction therapy for stage 4 neuroblastoma in children over 1 year of age.

scientific article published on December 1994

How effective is dose-intensive/myeloablative therapy against Ewing's sarcoma/primitive neuroectodermal tumor metastatic to bone or bone marrow? The Memorial Sloan-Kettering experience and a literature review

scientific article

Humanized 3F8 Anti-GD2 Monoclonal Antibody Dosing With Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Resistant Neuroblastoma: A Phase 1 Clinical Trial

scientific article published on 01 December 2018

Hyperfractionated low-dose (21 Gy) radiotherapy for cranial skeletal metastases in patients with high-risk neuroblastoma.

scientific article published on 8 May 2009

Hyperfractionated low-dose radiotherapy for high-risk neuroblastoma after intensive chemotherapy and surgery

scientific article

Hypothyroidism after 131I-monoclonal antibody treatment of neuroblastoma

scientific article published in July 2010

IMMU-05. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3

Ifosfamide, carboplatin, and etoposide for neuroblastoma: a high-dose salvage regimen and review of the literature

scientific article published on 05 September 2012

Impact of metaiodobenzylguanidine scintigraphy on assessing response of high-risk neuroblastoma to dose-intensive induction chemotherapy.

scientific article published in March 2003

Induction for high-risk neuroblastoma

scientific article published on 01 September 2007

International neuroblastoma staging system stage 1 neuroblastoma: a prospective study and literature review

scientific article published on July 1996

Irinotecan plus temozolomide for relapsed or refractory neuroblastoma.

scientific article

Key role for myeloid cells: phase II results of anti-G(D2) antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma

scientific article

Lack of survival advantage with autologous stem-cell transplantation in high-risk neuroblastoma consolidated by anti-GD2 immunotherapy and isotretinoin

scientific article published on 26 November 2015

Liver involvement in neuroblastoma: the Memorial Sloan-Kettering Experience supports treatment reduction in young patients

scientific article published on 01 March 2006

Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma

scientific article published on 27 May 2016

Local control with multimodality therapy for stage 4 neuroblastoma

scientific article published on 01 March 2000

Long-term Pulmonary Outcomes in Pediatric Survivors of High-risk Neuroblastoma.

scientific article published on 7 July 2017

Long-term complications in survivors of advanced stage neuroblastoma

scientific article published in September 2005

Long-term event-free survival after intensive chemotherapy for Ewing's family of tumors in children and young adults.

scientific article published in September 2003

MYCN-amplified stage 2/3 neuroblastoma: excellent survival in the era of anti-GD2 immunotherapy.

scientific article published on 24 August 2017

Management and outcome of stage 3 neuroblastoma

scientific article

Monoclonal antibody 3F8 can effect durable remissions in neuroblastoma patients refractory to chemotherapy: a phase II trial

scientific article published on 01 January 1991

Monoclonal antibody-based therapy of neuroblastoma

scientific article

Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remission

scientific article

Myeloablative chemotherapy with autologous stem cell transplant for desmoplastic small round cell tumor

scientific article published on 7 April 2015

Myeloablative combination chemotherapy without total body irradiation for neuroblastoma

scientific article published on 01 February 1991

N7: a novel multi-modality therapy of high risk neuroblastoma (NB) in children diagnosed over 1 year of age.

scientific article published in January 2001

Neonatal screening and management of biologically low-risk localized neuroblastoma

scientific article published on 01 May 1995

Neuroblastoma

scientific article published on 01 April 1988

Neuroblastoma and treatment-related myelodysplasia/leukemia: the Memorial Sloan-Kettering experience and a literature review

scientific article published on 01 December 1998

Neuroblastoma in adolescents and adults: the Memorial Sloan-Kettering experience

scientific article published in December 2003

Neuroblastoma--from genetic profiles to clinical challenge

scientific article published on 01 November 2005

Neuroblastoma--linking a common allele to a rare disease

scientific article published on 07 May 2008

Oral etoposide for refractory and relapsed neuroblastoma.

scientific article

Oral topotecan for refractory and relapsed neuroblastoma: a retrospective analysis

scientific article published in August 2003

Osteochondroma in long-term survivors of high-risk neuroblastoma

scientific article published on 27 February 2015

Ototoxicity from high-dose use of platinum compounds in patients with neuroblastoma

scientific article published in July 2006

PDCT-04. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3 IN PATIENTS WITH CNS/LM DISEASE

scientific article published on 06 November 2017

Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission

scientific article published on 11 February 2014

Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival.

scientific article published on 31 July 2017

Phase II trial of the anti-G(D2) monoclonal antibody 3F8 and granulocyte-macrophage colony-stimulating factor for neuroblastoma

scientific article published on 01 November 2001

Pilot study of topotecan and high-dose cyclophosphamide for resistant pediatric solid tumors.

scientific article published in November 2000

Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma

scientific article published on 17 March 2011

Posterior reversible encephalopathy syndrome in neuroblastoma patients receiving anti-GD2 3F8 monoclonal antibody

scientific article

Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections

scientific article published on October 2010

Prolonged progression-free survival after consolidating second or later remissions of neuroblastoma with Anti-GD2 immunotherapy and isotretinoin: a prospective Phase II study

scientific article published on 22 May 2015

Quantitation of GD2 synthase mRNA by real-time reverse transcriptase polymerase chain reaction: clinical utility in evaluating adjuvant therapy in neuroblastoma

scientific article published on 01 March 2003

Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8

scientific article published on 01 June 2002

Radiation Therapy to Sites of Metastatic Disease as Part of Consolidation in High-Risk Neuroblastoma: Can Long-term Control Be Achieved?

scientific article published on 9 January 2018

Radically different treatment recommendations for newly diagnosed neuroblastoma: pitfalls in assessment of risk.

scientific article published in January 2004

Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities

scientific article

Recurrent metastatic neuroblastoma followed by myelodysplastic syndrome: possible leukemogenic role of temozolomide

scientific article

Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma

scientific article

Reduced toxicity with intensity modulated radiation therapy (IMRT) for desmoplastic small round cell tumor (DSRCT): an update on the whole abdominopelvic radiation therapy (WAP-RT) experience

scientific article published on 17 October 2012

Reduced-Dose Radiation Therapy to the Primary Site is Effective for High-Risk Neuroblastoma: Results From a Prospective Trial

scientific article published on 11 February 2019

Reduced-dose craniospinal irradiation for central nervous system relapsed neuroblastoma

scientific article published on 01 July 2020

Reduction from seven to five cycles of intensive induction chemotherapy in children with high-risk neuroblastoma

scientific article

Renal Function Outcomes of High-risk Neuroblastoma Patients Undergoing Radiation Therapy.

scientific article published on 11 April 2017

Reply to L. Moreno et al.

scientific article published in February 2013

Rethinking management of localized neuroblastoma

scientific article published on 01 September 1993

Risks outweighed benefits from local radiation for non-stage 4 neuroblastoma

scientific article published on 01 December 2002

SCDT-38. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3 IN PATIENTS WITH CNS/LM DISEASE

scientific article published on 06 November 2017

Salvage rates after progression of high-risk neuroblastoma with a soft tissue mass

scientific article published on 5 November 2015

Sensitivity of surveillance studies for detecting asymptomatic and unsuspected relapse of high-risk neuroblastoma.

scientific article published on 26 January 2009

Short Hypofractionated Radiation Therapy in Palliation of Pediatric Malignancies: Outcomes and Toxicities

scientific article published on 02 August 2018

Short-Interval Retreatment With Stereotactic Body Radiotherapy (SBRT) for Pediatric Neuroblastoma Resulting in Severe Myositis

scientific article

Should we replace bone scintigraphy plus CT with MR imaging for staging of neuroblastoma?

scientific article published in January 2003

Solitary relapse of desmoplastic small round cell tumor detected by positron emission tomography/computed tomography

scientific article published on 22 September 2008

Specific gene expression profiles and chromosomal abnormalities are associated with infant disseminated neuroblastoma

scientific article

Stage 4 neuroblastoma diagnosed at more than 1 year of age: gross total resection and clinical outcome

scientific article published on 01 August 1994

Stage IV neuroblastoma more than 1 year of age at diagnosis: major response to chemotherapy and survival durations correlated strongly with dose intensity

scientific article published on 01 January 1991

Striking dichotomy in outcome of MYCN-amplified neuroblastoma in the contemporary era.

scientific article

Successful multifold dose escalation of anti-GD2 monoclonal antibody 3F8 in patients with neuroblastoma: a phase I study.

scientific article

Successful treatment of metastatic retinoblastoma

scientific article published on 01 November 2000

Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma with Prior Disease Progression

scientific article published on 16 December 2020

Survival from locally invasive or widespread neuroblastoma without cytotoxic therapy

scientific article published in February 1996

Survival from non-stage 4 neuroblastoma without cytotoxic therapy: an analysis of clinical and biological markers

article

Synovial sarcoma mimicking desmoplastic small round-cell tumor: critical role for molecular diagnosis

scientific article published on 01 February 1999

Targeted radiotherapy and immunotherapy of human neuroblastoma with GD2 specific monoclonal antibodies

scientific article published on January 1989

The impact of gross total resection on local control and survival in high-risk neuroblastoma

scientific article published on March 2004

Topotecan combined with myeloablative doses of thiotepa and carboplatin for neuroblastoma, brain tumors, and other poor-risk solid tumors in children and young adults

scientific article

Topotecan, thiotepa, and carboplatin for neuroblastoma: failure to prevent relapse in the central nervous system

scientific article published in February 2006

Transient sialoadenitis: a complication of 131I-metaiodobenzylguanidine therapy

scientific article published in June 2008

Treatment and outcome of adult-onset neuroblastoma.

scientific article published on 25 March 2018

Treatment and revaccination of children with paraneoplastic opsoclonus-myoclonus-ataxia syndrome and neuroblastoma: The Memorial Sloan Kettering experience

scientific article published on 15 June 2020

Treatment of spinal involvement in neuroblastoma patients.

scientific article published on December 2003

Treatment reduction for neuroblastoma

scientific article published on 01 November 2004

Tumor lysis syndrome, neuroblastoma, and correlation between serum lactate dehydrogenase levels and MYCN-amplification

scientific article published in July 2003

Very-high-dose short-term chemotherapy for poor-risk peripheral primitive neuroectodermal tumors, including Ewing's sarcoma, in children and young adults

scientific article published on 01 November 1995

What factors predict a favorable outcome in young children with disseminated neuroblastoma?

scientific article published on 01 May 2006

When overall survival fails to confirm event-free survival, should the latter be used to set the standard of care?

scientific article published on 17 November 2014

Whole abdominopelvic radiotherapy for desmoplastic small round-cell tumor

scientific article

Whole neuraxis irradiation to address central nervous system relapse in high-risk neuroblastoma

scientific article published on 6 March 2010

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