List of works - Justin Pollara

116. Role of Maternal Antibodies in Protection Against Postnatal Cytomegalovirus Acquisition

Adjuvant-dependent enhancement of HIV Env-specific antibody responses in infant rhesus macaques

article

An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates.

scientific article

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

scientific article

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

scientific article

Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay

scientific article published on 2 March 2018

Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1

scientific article

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

scientific article

Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency

scientific article published on 31 January 2020

Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction

scientific article published on 09 August 2018

Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk

scientific article published on 2 March 2016

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

scientific article

Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus

scientific article published on 06 July 2016

Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses

scientific article published on July 2013

Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials

scientific article

Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001

scientific article published on 14 September 2016

HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions

article published in the Proceedings of the National Academy of Sciences of the United States of America

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

scientific article published on 30 January 2020

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

scientific article published on 30 July 2015

HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

scientific article published on 2 May 2012

HIV-1 specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galcer Blocking and Phagocytosis

scientific article published on 10 January 2018

HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities

scientific article

HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies

scientific article

High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers

scientific article

High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses

scientific article (publication date: August 2011)

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

scientific article

Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection

scientific article

Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses

scientific article

Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid ⬇️

scientific article published on October 1, 2010

Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal

article

Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum

scientific article

Lessons learned from human HIV vaccine trials

scientific article

Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.

scientific article published on 10 January 2018

Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission

scientific article

Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication

scientific article published on September 2009

Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk

scientific article published on 17 April 2013

Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

scientific article

Oral co-administration of an intramuscular DNA/ Modified Vaccinia Ankara vaccine for simian immunodeficiency virus is associated with better control of infection in orally exposed infant macaques

scientific article published on 27 November 2018

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

scientific article

Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.

scientific article

Production of prostaglandin E2 in response to infection with modified vaccinia Ankara virus ⬇️

scientific article published on April 23, 2012

Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure

scientific article published on 16 January 2013

Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

scientific article published on 22 July 2020

Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s

scientific article published on 06 January 2022

The Impact of Poxvirus Vector Priming, Protein Co-Administration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques

scientific article

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

scientific article published on 08 December 2016

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

scientific article

Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide

scientific article

Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.

scientific article published on 9 May 2013

List of works by Justin Pollara

116. Role of Maternal Antibodies in Protection Against Postnatal Cytomegalovirus Acquisition

Adjuvant-dependent enhancement of HIV Env-specific antibody responses in infant rhesus macaques

An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates.

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay

Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency

Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction

Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus

Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses

Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials

Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001

HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

HIV-1 specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galcer Blocking and Phagocytosis

HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities

HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies

High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers

High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection

Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses

Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid ⬇️

Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal

Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum

Lessons learned from human HIV vaccine trials

Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.

Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission

Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication

Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk

Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

Oral co-administration of an intramuscular DNA/ Modified Vaccinia Ankara vaccine for simian immunodeficiency virus is associated with better control of infection in orally exposed infant macaques

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.

Production of prostaglandin E2 in response to infection with modified vaccinia Ankara virus ⬇️

Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure

Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s

The Impact of Poxvirus Vector Priming, Protein Co-Administration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide

Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.