List of works - Linda H Younkin

Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease

scientific article published in March 2007

Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline

scientific article

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

scientific article

Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein

scientific article

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

scientific article published in February 2002

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

scientific article

Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene

scientific article published on 22 December 2004

Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease

scientific article

Erratum to: Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility

scientific article published on 23 September 2015

Fine mapping of the -T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees ⬇️

scientific article published on October 14, 2003

Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease

scientific article

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

scientific article

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility

scientific article published on 9 April 2015

Identification of loci determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression

scientific article published on 14 July 2004

Increased aggression in males in transgenic Tg2576 mouse model of Alzheimer's disease

scientific article

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

scientific article published on 4 February 2013

LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD).

scientific article

Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice.

scientific article published in July 2005

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

scientific article (publication date: 15 January 2004)

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

scientific article

P4-095 Analysis of Alzheimer's disease candidate genes on chromosome 10

article

Peptide Nucleic Acids Targeted to the Amyloid Precursor Protein ⬇️

scientific article published on January 1, 2003

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

scientific article

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

scientific journal article

Serum creatinine levels correlate with plasma amyloid Beta protein

scientific article published in July 2002

Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy.

scientific article published on January 2013

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

scientific article published in August 2004

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

scientific article

Using peptide nucleic acids as gene-expression modifiers to reduce beta-amyloid levels

scientific article

List of works by Linda H Younkin

Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease

Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene

Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease

Erratum to: Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility

Fine mapping of the -T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees ⬇️

Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility

Identification of loci determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression

Increased aggression in males in transgenic Tg2576 mouse model of Alzheimer's disease

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD).

Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice.

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

P4-095 Analysis of Alzheimer's disease candidate genes on chromosome 10

Peptide Nucleic Acids Targeted to the Amyloid Precursor Protein ⬇️

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

Serum creatinine levels correlate with plasma amyloid Beta protein

Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy.

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

Using peptide nucleic acids as gene-expression modifiers to reduce beta-amyloid levels