List of works - Clifford W. Shults

A possible role of coenzyme Q10 in the etiology and treatment of Parkinson's disease

scientific article

A single intramesencephalic injection of brain-derived neurotrophic factor induces persistent rotational asymmetry in rats

scientific article

Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q 10 in parkinsonian patients ⬇️

scientific article published on March 1, 1998

Alpha-synuclein overexpression in oligodendrocytic cells results in impaired adhesion to fibronectin and cell death

scientific article

An examination of the nature of attentional deficits in patients with Parkinson's disease: evidence from a spatial orienting task

scientific article published on July 1, 1997

Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease

scientific article published on November 2003

Calf venous compliance in multiple system atrophy

scientific article published on 02 March 2007

Carbidopa/levodopa and selegiline do not affect platelet mitochondrial function in early parkinsonism

scientific article

Clinical correlates of depressive symptoms in familial Parkinson's disease

scientific article

Clinical improvement in parkinsonian patients undergoing adrenal to caudate transplantation is not reflected by chromogranin A or basic fibroblast growth factor in ventricular fluid.

scientific article published in March 1991

Clinical trials of coenzyme Q10 in neurological disorders

scientific article published on January 2005

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials

scientific article

Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice ⬇️

scientific article published on February 2, 1998

Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects ⬇️

scientific article published on August 1, 1997

Comparison of substance K-like and substance P-like fibers and cells in the rat hippocampus

scientific article

Detection of mild cognitive deficits in Parkinson's disease patients with the WAIS-R NI.

scientific article

Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS).

scientific article published in December 2004

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

scientific article

Effects of Coenzyme Q10 in Huntington's disease and early Parkinson's disease

scientific article published on January 2003

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

scientific article

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

scientific article published in April 2004

Evaluation of the role of Nurr1 in a large sample of familial Parkinson's disease

scientific article published in June 2004

G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy

scientific article

Genes influencing Parkinson disease onset: replication of PARK3 and identification of novel loci

scientific article

Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease

scientific article published in The Lancet

Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations

scientific article published on 07 June 2002

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease

article

Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease

scientific article

LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8.

scientific article published on 5 September 2007

Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease

scientific article

Measuring the effects of therapy in Parkinson disease

scientific article published on 01 May 2004

Mutations in DJ-1 are rare in familial Parkinson disease

scientific article

Mutations in LRRK2 other than G2019S are rare in a north american–based sample of familial Parkinson's disease

article

Natural history of multiple system atrophy in the USA: a prospective cohort study

scientific article

Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.

scientific article published on November 2005

Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease

scientific article

Potential outcome measures and trial design issues for multiple system atrophy

scientific article published in December 2007

Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia

scientific article published in January 2006

Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure

scientific article

R1514Q substitution in Lrrk2 is not a pathogenic Parkinson's disease mutation

article

Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy

scientific article

Significant linkage of Parkinson disease to chromosome 2q36-37

scientific article

Storage, metabolism, and processing of 125I-fibroblast growth factor-2 after intracerebral injection.

scientific article

The North American Multiple System Atrophy Study Group

scientific article

The role of radiotracer imaging in Parkinson disease

scientific article

Visual attention and perception in patients with Huntington's disease: comparisons with other subcortical and cortical dementias.

scientific article published in October 1995

alpha-synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy

scientific article published on 9 August 2006

List of works by Clifford W. Shults

A possible role of coenzyme Q10 in the etiology and treatment of Parkinson's disease

A single intramesencephalic injection of brain-derived neurotrophic factor induces persistent rotational asymmetry in rats

Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q 10 in parkinsonian patients ⬇️

Alpha-synuclein overexpression in oligodendrocytic cells results in impaired adhesion to fibronectin and cell death

An examination of the nature of attentional deficits in patients with Parkinson's disease: evidence from a spatial orienting task

Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease

Calf venous compliance in multiple system atrophy

Carbidopa/levodopa and selegiline do not affect platelet mitochondrial function in early parkinsonism

Clinical correlates of depressive symptoms in familial Parkinson's disease

Clinical improvement in parkinsonian patients undergoing adrenal to caudate transplantation is not reflected by chromogranin A or basic fibroblast growth factor in ventricular fluid.

Clinical trials of coenzyme Q10 in neurological disorders

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials

Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice ⬇️

Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects ⬇️

Comparison of substance K-like and substance P-like fibers and cells in the rat hippocampus

Detection of mild cognitive deficits in Parkinson's disease patients with the WAIS-R NI.

Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS).

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

Effects of Coenzyme Q10 in Huntington's disease and early Parkinson's disease

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

Evaluation of the role of Nurr1 in a large sample of familial Parkinson's disease

G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy

Genes influencing Parkinson disease onset: replication of PARK3 and identification of novel loci

Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease

Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease

Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease

LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8.

Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease

Measuring the effects of therapy in Parkinson disease

Mutations in DJ-1 are rare in familial Parkinson disease

Mutations in LRRK2 other than G2019S are rare in a north american–based sample of familial Parkinson's disease

Natural history of multiple system atrophy in the USA: a prospective cohort study

Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.

Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease

Potential outcome measures and trial design issues for multiple system atrophy

Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia

Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure

R1514Q substitution in Lrrk2 is not a pathogenic Parkinson's disease mutation

Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy

Significant linkage of Parkinson disease to chromosome 2q36-37

Storage, metabolism, and processing of 125I-fibroblast growth factor-2 after intracerebral injection.

The North American Multiple System Atrophy Study Group

The role of radiotracer imaging in Parkinson disease

Visual attention and perception in patients with Huntington's disease: comparisons with other subcortical and cortical dementias.

alpha-synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy