List of works - Evert J Homan

Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

scientific article

Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

scientific article published in April 2017

Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

scientific article published on 29 November 2016

Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target

scientific article published on 22 June 2020

Development of a chemical probe against NUDT15

scientific article published on 20 July 2020

Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space

scientific article published on 20 September 2017

Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition

scientific article

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

scientific article

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

scientific article

MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP

scientific article published on 01 November 2018

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine

scientific article

Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction.

scientific article published on 11 September 2017

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

scientific article

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

scientific article

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

scientific article published on 17 January 2018

dUTPase inhibition augments replication defects of 5-Fluorouracil.

scientific article published on April 2017

List of works by Evert J Homan

Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target

Development of a chemical probe against NUDT15

Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space

Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine

Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction.

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

dUTPase inhibition augments replication defects of 5-Fluorouracil.