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List of works by Akimitsu Takahashi

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

scientific article published on 02 June 2014

Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status

scientific journal article

Circulating malondialdehyde-modified LDL-related variables and coronary artery stenosis in asymptomatic patients with type 2 diabetes

scientific article

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.

scientific article

Comparison of the Framingham risk score, UK Prospective Diabetes Study (UKPDS) Risk Engine, Japanese Atherosclerosis Longitudinal Study-Existing Cohorts Combine (JALS-ECC) and maximum carotid intima-media thickness for predicting coronary artery ste

scientific article published on 8 April 2014

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of L

scientific article published in May 2003

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling

scientific article published on May 2003

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

scientific article published on 30 September 2007

Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha

scientific article published in January 2002

Elovl6 promotes nonalcoholic steatohepatitis

scientific article published on 01 December 2012

Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice

scientific journal article

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.

scientific article published on 18 September 2014

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice

scientific article published on 12 September 2011

Macrophage Elovl6 Deficiency Ameliorates Foam Cell Formation and Reduces Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

scientific article published on 04 August 2011

Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets

scientific article published on 5 May 2008

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

scientific article

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver

scientific article published on 12 February 2007

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

scientific article

SREBPs suppress IRS-2-mediated insulin signalling in the liver

scientific article published on 14 March 2004

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

scientific article published on 14 September 2015

Sterol Regulatory Element–Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

scientific article published on 05 May 2011

TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice

scientific article

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

scientific article published on 4 December 2005

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