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List of works by Marc M Loriaux

AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

scientific article

Activating alleles of JAK3 in acute megakaryoblastic leukemia

scientific article published on July 2006

An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma

scientific article published on 30 August 2012

CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

scientific article published on 19 October 2010

CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms

scientific article

Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine

scientific article

Crosstalk between ROR1 and the Pre-B cell receptor promotes survival of t(1;19) acute lymphoblastic leukemia

scientific article

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

scientific article published on 5 February 2008

High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

scientific article published on 15 December 2008

HitWalker: variant prioritization for personalized functional cancer genomics

scientific article

Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth

scientific article

In vitro sensitivity to dasatinib in lymphoblasts from a patient with t(17;19)(q22;p13) gene rearrangement pre-B acute lymphoblastic leukemia

scientific article published on 28 October 2011

Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening

scientific article

MET receptor sequence variants R970C and T992I lack transforming capacity

scientific article

Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML

scientific article

Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies

scientific article published on 11 April 2011

RNAi screen for rapid therapeutic target identification in leukemia patients

scholarly article

RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia

scientific article

The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition

scientific article published on 30 September 2013

The selective SYK inhibitor P505-15 (PRT062607) inhibits B cell signaling and function in vitro and in vivo and augments the activity of fludarabine in chronic lymphocytic leukemia

scientific article published on 7 December 2012

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