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List of works by Michael A Beaven

A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses

scientific article

A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells

scientific article published on 02 May 2013

Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33.

scientific article published on 8 August 2015

Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit

scientific article published on 21 September 2005

Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cells

scientific article

Concurrent inhibition of kit- and FcepsilonRI-mediated signaling: coordinated suppression of mast cell activation

scientific article published on 09 October 2007

Distinct PGE2-responder and non-responder phenotypes in human mast cell populations: “All or nothing” enhancement of antigen-dependent mediator release ⬇️

scientific article published on July 20, 2011

Examination of the role of TRPM8 in human mast cell activation and its relevance to the etiology of cold-induced urticaria ⬇️

scientific article published on September 8, 2011

IL-33 induces a hyporesponsive phenotype in human and mouse mast cells.

scientific article published on 17 December 2012

IL-6 promotes an increase in human mast cell numbers and reactivity through suppression of suppressor of cytokine signaling 3.

scientific article published on 07 January 2016

Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells

scientific article

Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production

scientific article published on 13 March 2013

Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells

scientific article

Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release ⬇️

scientific article published on October 27, 2010

Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation

scientific article

Stem cell factor programs the mast cell activation phenotype

scientific article

Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release

scientific article published on 22 January 2008

The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling

scientific article

The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

scientific article published on December 2008

The phospholipase C gamma 1-dependent pathway of Fc epsilon RI-mediated mast cell activation is regulated independently of phosphatidylinositol 3-kinase

scientific article published on 16 September 2003

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