List of works by Aldo Clerico

A Black Swan in clinical laboratory practice: the analytical error due to interferences in immunoassay methods

scientific article published on 7 December 2017

ANMCO/ELAS/SIBioC Consensus Document: biomarkers in heart failure.

scientific article published on 2 May 2017

Adiponectin plasma levels decrease after surgery in pediatric patients with congenital heart disease.

scientific article published on 22 July 2012

Aerobic training decreases B-type natriuretic peptide expression and adrenergic activation in patients with heart failure

scientific article published on 19 April 2006

Analysis of the 2010-2012 results of the multicenter external proficiency study for 25-hydroxyvitamin D

scientific article published on 01 October 2013

Analysis of the variation in the hsp70-1 and hsp90alpha mRNA expression in human myocardial tissue that has undergone surgical stress

scientific article published on January 2003

Analytical performance and clinical results of a fully automated MEIA system for brain natriuretic peptide assay: comparison with a point of care testing method.

scientific article published in January 2004

Analytical performance and diagnostic accuracy of a fully-automated electrochemiluminescent assay for the N-terminal fragment of the pro-peptide of brain natriuretic peptide in patients with cardiomyopathy: comparison with immunoradiometric assay me

scientific article published in January 2004

Analytical performance and diagnostic accuracy of immunometric assays for the measurement of plasma B-type natriuretic peptide (BNP) and N-terminal proBNP.

scientific article

Association between 5,10-Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Conotruncal Heart Defects ⬇️

scientific article published on March 1, 2003

BNP in children with congenital cardiac disease: is there now sufficient evidence for its routine use?

scientific article

Biomarkers of activation of renin-angiotensin-aldosterone system in heart failure: how useful, how feasible?

scientific article

C-peptide and insulin assays with the Mindray CL-2000i: Precision and comparability with different methods

scientific article published on 09 April 2019

C-type natriuretic peptide expression in patients with chronic heart failure: effects of aerobic training

scientific article published on 01 April 2008

Cardiac biomarker testing in the clinical laboratory: where do we stand? General overview of the methodology with special emphasis on natriuretic peptides

scientific article

Cardiac biomarkers and risk assessment in patients undergoing major non-cardiac surgery: time to revise the guidelines?

scientific article

Cardiac endocrine function is an essential component of the homeostatic regulation network: physiological and clinical implications.

scientific article

Cardiac natriuretic hormones, neuro-hormones, thyroid hormones and cytokines in normal subjects and patients with heart failure.

scientific article published in January 2004

Cardiovascular biomarkers: increasing impact of laboratory medicine in cardiology practice

scientific article published on January 2008

Circulating forms of the b-type natriuretic peptide prohormone: pathophysiologic and clinical considerations

scientific article published on January 2012

Clinical relevance of biological variation of B-type natriuretic peptide

scientific article published in May 2005

Clinical relevance of biological variation: the lesson of brain natriuretic peptide (BNP) and NT-proBNP assay.

scientific article

Clinical relevance of measurement of brain natriuretic peptide and N-terminal pro-brain natriuretic peptide in pediatric cardiology

scientific article

Clinical relevance of non-cardiac determinants of natriuretic peptide levels.

scientific article published on January 2008

Clinical relevance of time course of BNP levels in neonates with congenital heart diseases

scientific article published on 3 September 2011

Comparison between BNP values measured in capillary blood samples with a POCT method and those measured in plasma venous samples with an automated platform

scientific article published in April 2015

Comparison between analytical performances of polyclonal and monoclonal electrochemiluminescence immunoassays for NT-proBNP.

scientific article

Comparison of a fully automated immunoassay with a point-of-care testing method for B-type natriuretic peptide

scientific article published in July 2005

Comparison of brain natriuretic peptide (BNP) and amino-terminal ProBNP for early diagnosis of heart failure

scientific article

Comparison of the diagnostic accuracy of brain natriuretic peptide (BNP) and the N-terminal part of the propeptide of BNP immunoassays in chronic and acute heart failure: a systematic review.

scientific article

Coronary artery bypass grafting surgery is associated with a marked reduction in serum homocysteine and folate levels in the early postoperative period.

scientific article published in October 2004

Decision levels for plasma B-type natriuretic peptide assay to diagnose significant cardiovascular disease in children.

scientific article published in March 2010

Deoxyribonucleic acid damage in human lymphocytes after percutaneous transluminal coronary angioplasty

scientific article

Detection of mtDNA with 4977 bp deletion in blood cells and atherosclerotic lesions of patients with coronary artery disease.

scientific article published in February 2005

Diagnostic accuracy and clinical relevance of brain natriuretic peptide assay in pediatric patients with congenital heart diseases.

scientific article

Diagnostic accuracy and prognostic relevance of the measurement of cardiac natriuretic peptides: a review

scientific article

Diagnostic accuracy and prognostic valued of plasmatic Cystatin-C in children undergoing pediatric cardiac surgery

scientific article published on 25 May 2017

Diagnostic accuracy of B-type natriuretic hormone for congenital heart disease in the first month of life

scientific article published on 01 September 2010

Diagnostic, prognostic and therapeutic relevance of B-type natriuretic hormone and related peptides in children with congenital heart diseases.

scientific article

Direct comparison of B-type natriuretic peptide (BNP) and amino-terminal proBNP in a large population of patients with chronic and symptomatic heart failure: the Valsartan Heart Failure (Val-HeFT) data

scientific article

Distribution of plasma cardiac troponin I values in healthy subjects: pathophysiological considerations

scientific article

Endothelial function and carotid intima-media thickness in young healthy subjects among endothelial nitric oxide synthase Glu298-->Asp and T-786-->C polymorphisms

scientific article published on 8 April 2004

Endothelial nitric oxide synthase gene polymorphisms and risk of coronary artery disease

scientific article published on 01 March 2003

Evaluation of analytical performance and comparison of clinical results of the new generation method AccuTnI+3 for the measurement of cardiac troponin I using both patients and quality control plasma samples

scientific article published on 21 September 2015

Evaluation of analytical performance of a chemiluminescence enzyme immunoassay (CLEIA) for cTnI using the automated AIA-CL2400 platform

scientific article published on 19 January 2018

Evaluation of analytical performance of a new high-sensitivity immunoassay for cardiac troponin I.

scientific article

Evaluation of analytical performance of the Siemens ADVIA TnI ultra immunoassay

scientific article published on 01 September 2007

Evaluation of analytical performances using standardized analytical protocols and comparison of clinical results of the new ADVIA BNP and NT-proBNP immunoassays for the Centaur XPT platform

scientific article published on 01 May 2019

Evaluation of the analytical performance of a new ADVIA immunoassay using the Centaur XPT platform system for the measurement of cardiac troponin I.

scientific article published on 21 April 2018

Evaluation of the analytical performance of the advanced method for cardiac troponin I for the AxSYM platform: comparison with the old method and the Access system

scientific article published on 01 January 2006

Free triiodothyronine: a novel predictor of postoperative atrial fibrillation.

scientific article published in October 2003

Gene silencing of endothelial von Willebrand Factor attenuates angiotensin II-induced endothelin-1 expression in porcine aortic endothelial cells.

scientific article published on 22 July 2016

Harmonization of two hs-cTnI methods based on recalibration of measured quality control and clinical samples

scientific article published on 08 July 2020

Harmonization protocols for TSH immunoassays: a multicenter study in Italy

scientific article

Harmonization protocols for thyroid stimulating hormone (TSH) immunoassays: different approaches based on the consensus mean value.

scientific article published in February 2015

Heat shock protein 70-1 gene expression in pediatric heart surgery using blood cardioplegia

scientific article published on January 2007

High-sensitivity cardiac troponin I and T methods for the early detection of myocardial injury in patients on chemotherapy

scientific article published on 22 May 2020

High-sensitivity troponin: a new tool for pathophysiological investigation and clinical practice

scientific article published on January 2009

Hypovitaminosis D in patients with heart failure: effects on functional capacity and patients' survival.

scientific article published on 23 March 2017

Imaging and laboratory biomarkers in cardiovascular disease

scientific article published on January 2009

Influence of gender on circulating cardiac natriuretic hormones in patients with heart failure

scientific article published in May 2003

Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk.

scientific article

Low triiodothyronine and exercise capacity in heart failure

scientific article published on 02 October 2010

Markers of fibrosis, inflammation, and remodeling pathways in heart failure.

scientific article published on 10 September 2014

Measurement of circulating concentrations of cardiac troponin I and T in healthy subjects: a tool for monitoring myocardial tissue renewal?

scientific article published on January 2009

Measurement of the pro-hormone of brain type natriuretic peptide (proBNP): methodological considerations and pathophysiological relevance.

scientific article published on 26 August 2011

Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease

scientific article

Multicentre comparison of free thyroid hormones immunoassays: the Immunocheck study.

scientific article published on 17 June 2011

N-terminal prob-type natriuretic peptide is a marker of vascular remodelling and subclinical atherosclerosis in asymptomatic hypertensives

scientific article published on 2 February 2015

Natriuretic peptide system and the heart.

scientific article

Natriuretic peptide testing in primary care patients.

scientific article published on January 2008

Natriuretic peptides (NPs): Automated electrochemiluminescent immunoassay for N-terminal pro-BNP compared with IRMAs for ANP and BNP in heart failure patients and healthy individuals

scientific article published in September 2003

Natriuretic peptides as biomarkers of cardiac endocrine function in heart failure: new challenges and perspectives.

scientific article published on 27 July 2016

Natriuretic peptides. D'où venons-nous? Que sommes-nous? Où allons-nous?

scientific article

Neuro-hormonal activation predicts ventilatory response to exercise and functional capacity in patients with heart failure.

scientific article

Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker of acute kidney injury: a review of the laboratory characteristics and clinical evidences

scientific article published on 15 February 2012

New and emerging biomarkers of heart failure

scientific article published on January 2009

New issues on measurement of B-type natriuretic peptides

scientific article published on 15 August 2017

Old and new biomarkers of heart failure.

scientific article published on April 2009

Pathophysiological and clinical relevance of circulating levels of cardiac natriuretic hormones: are they merely markers of cardiac disease?

scientific article

Percentile transformation and recalibration functions allow harmonization of thyroid-stimulating hormone (TSH) immunoassay results

scientific article published on 13 January 2020

Pilot study on harmonization of cardiac troponin I immunoassays using patients and quality control plasma samples. On behalf of the Italian Section of the European Ligand Assay Society (ELAS) and of the Study Group on Cardiovascular Biomarkers of th

scientific article published on 25 February 2016

Platelet activation predicts recurrent ischemic events after percutaneous coronary angioplasty: a 6 months prospective study

scientific article (publication date: 2006)

Platelet proteome and clopidogrel response in patients with stable angina undergoing percutaneous coronary intervention

scientific article

Proficiency testing project for brain natriuretic peptide (BNP) and the N-terminal part of the propeptide of BNP (NT-proBNP) immunoassays: the CardioOrmocheck study.

scientific article published in January 2009

Prognostic role of BNP in children undergoing surgery for congenital heart disease: analysis of prediction models incorporating standard risk factors.

scientific article published on 22 April 2015

Prognostic value of combined measurement of brain natriuretic peptide and triiodothyronine in heart failure

scientific article published on 4 October 2008

Proposal for the use in emergency departments of cardiac troponins measured with the latest generation methods in patients with suspected acute coronary syndrome without persistent ST-segment elevation.

scientific article published in September 2013

Recent advances on natriuretic peptide system: new promising therapeutic targets for the treatment of heart failure

scientific article published on 26 August 2013

Recommendations for the clinical use of cardiac natriuretic peptides

scientific article

Reference intervals for brain natriuretic peptide in healthy newborns and infants measured with an automated immunoassay platform.

scientific article

Reference values for plasma B-type natriuretic peptide in the first days of life.

scientific article published on 28 May 2009

Relationships between optical aggregometry (type born) and flow cytometry in evaluating ADP-induced platelet activation

scientific article (publication date: 2008)

Response of cardiac endocrine function to surgery stress is age dependent in neonates and children with congenital heart defects: consequences in diagnostic and prognostic accuracy of brain natriuretic peptide measurement

scientific article published in June 2013

Risk factors and prognostic value of daytime Cheyne-Stokes respiration in chronic heart failure patients.

scientific article published on 8 August 2008

SERCA2a, phospholamban, sarcolipin, and ryanodine receptors gene expression in children with congenital heart defects

scientific article

State of the art of BNP and NT-proBNP immunoassays: the CardioOrmoCheck study.

scientific article

State of the art of aldosterone immunoassays. A multicenter collaborative study on the behalf of the Cardiovascular Biomarkers Study Group of the Italian Section of European Society of Ligand Assay (ELAS) and Società Italiana di Biochimica Clinica (

scientific article published on 4 February 2015

State of the art of immunoassay methods for B-type natriuretic peptides: An update.

scientific article published on 30 December 2014

Supplemental nitric oxide and its effect on myocardial injury and function in patients undergoing cardiac surgery with extracorporeal circulation

scientific article published in January 2004

Systematic differences between BNP immunoassays: comparison of methods using standard protocols and quality control materials

scientific article published on 9 July 2013

The 99th percentile of reference population for cTnI and cTnT assay: methodology, pathophysiology and clinical implications.

scientific article

The circulating levels of cardiac natriuretic hormones in healthy adults: effects of age and sex.

scientific article

The combined use of neutrophil gelatinase-associated lipocalin and brain natriuretic peptide improves risk stratification in pediatric cardiac surgery

scientific article published in November 2012

The double balloon cannula: a means to prevent backward flow of retrograde cardioplegia to the right atrium

scientific article published on 02 March 2006

The increasing impact of laboratory medicine on clinical cardiology

scientific article

The low triiodothyronine syndrome: a strong predictor of low cardiac output and death in patients undergoing coronary artery bypass grafting

scientific article

The neuroendocrinal system of the heart after construction of a Glenn anastomosis or the Fontan circulation

scientific article published in December 2005

The non-thyroidal illness syndrome after coronary artery bypass grafting: a 6-month follow-up study.

scientific article

The paradox of low BNP levels in obesity

scientific article published on January 2012

The potential and limitations of plasma BNP measurement in the diagnosis, prognosis, and management of children with heart failure due to congenital cardiac disease: an update.

scientific article

The search for a pathophysiological link between gender, cardiac endocrine function, body mass regulation and cardiac mortality: proposal for a working hypothesis

scientific article published on 31 March 2009

Thirty years of the heart as an endocrine organ: physiological role and clinical utility of cardiac natriuretic hormones.

scientific article published on 06 May 2011

Thyroid and brain natriuretic Peptide response in children undergoing cardiac surgery for congenital heart disease- age-related variations and prognostic value

scientific article published on 27 September 2012

Thyroid function and cardiac surgery: what should we measure, and when?

scientific article published in March 2010

Understanding the clinical biochemistry of N-terminal pro-B-type natriuretic peptide: the prerequisite for its optimal clinical use.

scientific article published on January 2004

Usefulness of High-Sensitive Troponin Elevation After Effort Stress to Unveil Vulnerable Myocardium in Patients With Heart Failure.

scientific article published on 21 May 2015

[ANMCO/ELAS/SIBioC Consensus document: Recommendations for the use of cardiac biomarkers in heart failure patients].

scientific article published in September 2016

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