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List of works by Victor Ghetie

A CD4-derived peptide carrier blocks acute HIV-1 infection in vitro and binds to gp120 in the presence of Walter-Reed stage 1-6 HIV+ sera

scientific article published on 01 November 1992

A Phase I study with an anti-CD30 ricin A-chain immunotoxin (Ki-4.dgA) in patients with refractory CD30+ Hodgkin's and non-Hodgkin's lymphoma

scientific article published on 01 June 2002

A novel recombinant vaccine which protects mice against ricin intoxication.

scientific article

A phase 1 study of Combotox in pediatric patients with refractory B-lineage acute lymphoblastic leukemia

scientific article published on December 2009

A phase I study of a combination of anti‐CD19 and anti‐CD22 immunotoxins (Combotox) in adult patients with refractory B‐lineage acute lymphoblastic leukaemia ⬇️

scientific article published on 07 July 2011

A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy.

scientific article

A phase I study of bolus versus continuous infusion of the anti-CD19 immunotoxin, IgG-HD37-dgA, in patients with B-cell lymphoma.

scientific article

A phase I study of combination therapy with immunotoxins IgG-HD37-deglycosylated ricin A chain (dgA) and IgG-RFB4-dgA (Combotox) in patients with refractory CD19(+), CD22(+) B cell lymphoma

scientific article published on April 2000

A phase-I study of an anti-CD25 ricin A-chain immunotoxin (RFT5-SMPT-dgA) in patients with refractory Hodgkin's lymphoma

scientific article published on 01 January 1997

Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation

scientific article

An anti-CD45RO immunotoxin kills latently infected human immunodeficiency virus (HIV) CD4 T cells in the blood of HIV-positive persons

scientific article published on 8 January 2002

Anti-CD19 antibodies inhibit the function of the P-gp pump in multidrug-resistant B lymphoma cells.

scientific article published in December 1999

Anti-CD19 immunotoxin enhances the activity of chemotherapy in severe combined immunodeficient mice with human pre-B acute lymphoblastic leukemia

scientific article published on November 2006

Binding of cytophilic rabbit IgG to homologous hepatocytes ⬇️

scientific article published on June 15, 1979

CD4 peptide-protein conjugates, but not recombinant human CD4, bind to recombinant gp120 from the human immunodeficiency virus in the presence of serum from AIDS patients

scientific article published on July 1991

Chemical Construction of Immunotoxins

scientific article published on 01 January 2000

Chemical construction of immunotoxins

scientific article

Clinical Trials with an Anti-CD25 Ricin A-Chain Experimental and Immunotoxin (RFT5-SMPT-dgA) in Hodgkin's Lymphoma ⬇️

scientific article published on 01 August 1998

Clinical evaluation of ricin A-chain immunotoxins in patients with Hodgkin’s lymphoma ⬇️

scientific article published on 01 May 2003

Complete sustained response of a refractory, post-transplantation, large B-cell lymphoma to an anti-CD22 immunotoxin

scientific article published on 01 June 1997

Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160.

scientific article published on 19 October 2016

Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation

scientific article published on 01 August 2004

Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas

scientific article

Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy

scientific article published on 01 May 1988

Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome

scientific article

Fibronectin inhibits the cytotoxic effect of ricin A chain on endothelial cells

scientific article published on 01 June 1996

Generation and characterization of a novel tetravalent anti-CD22 antibody with improved antitumor activity and pharmacokinetics

scientific article published on 22 December 2005

Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice

scientific article published on 10 March 2003

HIV-infected cells are killed by rCD4-ricin A chain

scientific article

Identification of Human Anti-HIV gp160 Monoclonal Antibodies That Make Effective Immunotoxins

scientific article

Immunoconjugates containing ricin A chain and either human anti-gp41 or CD4 kill H9 cells infected with different isolates of HIV, but do not inhibit normal T or B cell function

scientific article published on January 1990

Immunology. Considering therapeutic antibodies

scientific article published in July 2006

Immunotoxins for the Treatment of B-Cell Lymphomas ⬇️

scientific article published on July 1, 1997

Interaction between rabbit IgG immune complexes and Ricinus agglutinin

scientific article published on 01 March 1986

Isolation of a rabbit IgG fraction with cytophilic properties ⬇️

scientific article published on May 13, 1983

Large scale preparation of an immunoconjugate constructed with human recombinant CD4 and deglycosylated ricin A chain

scientific article published on January 1990

Large scale preparation of immunotoxins constructed with the Fab' fragment of IgG1 murine monoclonal antibodies and chemically deglycosylated ricin A chain

scientific article published in September 1988

Optimized clinical-scale culture conditions for ex vivo selective depletion of host-reactive donor lymphocytes: a strategy for GvHD prophylaxis in allogeneic PBSC transplantation

scientific article published on 01 January 2002

Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration

scientific article

Phase I trial of an anti-CD19 deglycosylated ricin A chain immunotoxin in non-Hodgkin's lymphoma: effect of an intensive schedule of administration

scientific article published on 01 November 1995

Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers

scientific article published on January 1990

Purification and properties of immunotoxins containing one vs. two deglycosylated ricin A chains.

scientific article published in November 1993

Reconstitution of FOXP3+ regulatory T cells (Tregs) after CD25-depleted allotransplantation in elderly patients and association with acute graft-versus-host disease.

scientific article

Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation

scientific article published on 7 April 2005

Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses

scientific article published on 22 May 2003

The GLP large scale preparation of immunotoxins containing deglycosylated ricin A chain and a hindered disulfide bond

scientific article published in September 1991

The effect of a monoclonal antibody coupled to ricin A chain-derived peptides on endothelial cells in vitro: insights into toxin-mediated vascular damage

scientific article published on 01 August 2000

The epitope specificity and tissue reactivity of four murine monoclonal anti-CD22 antibodies

scientific article published on 01 January 1989

The evaluation of recombinant, chimeric, tetravalent antihuman CD22 antibodies

scientific article published on February 2004

The generation of immunotoxins using chimeric anti-CD22 antibodies containing mutations which alter their serum half-life

scientific article

The in vivo anti-tumor activity of immunotoxins containing two versus one deglycosylated ricin A chains

scientific article published on 01 November 1995

Treatment of SCID/human B cell precursor ALL with anti-CD19 and anti-CD22 immunotoxins

scientific article

Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin

scientific article published on 01 January 2000

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